Bullous pemphigoid penicillamine

Bullous pemphigoid frusemide (and other sulphonamide-related drugs), ACE inhibitors, penicillamine, penicillin, PUVA therapy. 

A consultation of the database of the Committee on Safety of Medicines in London showed that 41 cases of bullous pemphigoid have been reported in suspected connection with penicillamine, suggesting that this adverse reaction is less rare that the published literature suggests. 

Rasmussen HB, Jepsen LV, Brandrup F. Penicillamine-induced bullous pemphigoid with pemphigus-like antibodies. J Cutan Pathol 1989 16(3) 154-7. 

Weller R, White MI. Penicillamine in the etiology of bullous pemphigoid. Ann Pharmacother 1998 32(12) 1368. 

Common drugs that cause bullous eruptions and bullous pemphigoid are nadalol, penicillamine, piroxicam,... 

Bullous pemphigoid Tense Bullae, widespread Present or absent Furosemide, penicillamine, penicillins, sulfasalazine, captopril Supportive ... 

Another case of bullous pemphigoid has been described in a patient taking penicillamine [50 ]. 

Popadic S, Skiljevic D, Medenica L. Bullous pemphigoid induced by penicillamine in a patient with Wilson disease. Am J Clin Dermatol 2009 10(1) 36-8. 

Pemphigoid-type Pemphigoid-type reactions characterized by bullous lesions have required discontinuation of penicillamine and treatment with corticosteroids. 

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