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PECAM

Key PMN, polymorphonuclear leukocytes EC, endothelial cell lymphs, lymphocytes CD, cluster of differentiation iCAM, intercellular adhesion molecule LFA-1, lymphocyte function-associated antigen-1 PECAM-1, platelet endothelial cell adhesion cell molecule-1. [Pg.529]

Lynch DR, Guttmann RP (2002) Excitotoxicity perspectives based on N-methyl-D-aspartate receptor subtypes. J Pharmacol Exp Ther 300(3) 717-723 Magnuson DS, Knudsen BE, Geiger JD, Brownstone RM, Nath A (1995) Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity. Ann Neurol 37(3) 373-380 Mamdouh Z, Chen X, Kerini LM, Maxfield FR, Muller WA (2003) Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis. Nature 421(6924) 748-753... [Pg.27]

CD31 Known to be on platelets, monocytes, macrophages, granulocytes, B-ceUs and endothelial cells also known as PECAM CD32 Fc7 receptor II CD33 Known to be z monocyte and stem cell marker CD34 Known to be z stem cell marker... [Pg.280]

PE Phosphatidylethanolamine PECAM-1 Platelet endothelial cell adhesion molecule-1 also known as CD31... [Pg.285]

SHIP SH2 domain binds to the phosphorylated mM (p-ITIM) of other inhibitory co-receptors (gp49Bl) (Kuroiwa etal, 1998) and to the p-ITIM-like motif of the adhesion receptor, PECAM-1 (Pumphrey et al., 1999), furthermore, in vitro it binds to the phosphorylated immimoreceptor tyrosine based activation motifs (p-TTAM) within the p and y subunits of the high affinity IgE receptor (Kimura et al. 1997)), and the zeta chain of T cell receptor (Osborne et al, 1996). However, in vivo coprecipitation of these molecules was not observed. [Pg.313]

Platelets also express adhesion receptors of the selectin gene family (P-selectin) and of the immunoglobulin gene superfamily (PECAM-1 and ICAM-2) (6). Expression of PECAM-1 and ICAM-2 may play a role in platelet interactions with endothelial cells and leukocytes, respectively. [Pg.237]

Kroll H, Sun QH, Santoso S. Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a target glycoprotein in drug-induced thrombocytopenia. Blood 2000 96(4) 1409-14. [Pg.343]

Li, S., Tan, Y., Viroonchatapan, E., Pitt, B.R. and Huang, L. (2000) Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody. Am. J. Physiol., 278, L504-L511. [Pg.394]

Anti-platelet endothelial cell PECAM Endothelial cells [38]... [Pg.129]

Thai IM, Ashman LK, Flarbour SN, Flogarth PM, Jackson DE. Physical proximity and functional interplay of PECAM-1 with the Fc receptor Fc gamma Rlla on the platelet plasma membrane. Blood 2003 102(10) 3637-45. [Pg.265]

PECAM (Platelet Endothelial Cell Adhesion Molecule)... [Pg.309]

Duncan GS, Andrew DP, Takimoto H et al. (1999) Genetic evidence for functional redundancy of platelet/endothelial cell adhesion molecule-1 (PECAM-1) CD31-deficient mice reveal PECAM-1-dependent and PECAM-1-independent functions. J Immunol 162 3022-3030 Mahooti S, Graesser D, Patil S et al. (2000) PECAM-1 (CD 31) expression modulates bleeding time in vivo. Am J Pathol 157 75-81... [Pg.309]

The interaction of the various aP integrin complexes with ICAMs results in firm attachment and spreading. Subsequent VCAM-1-integrin and PECAM-1-integrin interactions are involved in leucocyte transmigration through endothelial cell junctions into the extravascular space. Leucocytes can thence proceed to interact with target cells and initiate inflammatory processes. [Pg.596]

VE)-cadherin and platelet endothelial cell adhesion molecule-1 (PECAM-1). VE-cadherin is an endothelial-specific Ca " -regulated protein that is linked to the cytoskeleton via catenins (Fig. 1). PECAM-1, also known as CD31, is a key participant in the migration of blood-borne cells across the BBB. Changes in the adherent junction proteins can lead to increased paracellular permeability (Abbruscato and Davis, 1999) and leukocyte trafficking in the CNS (Newman, 1994 Garrido-Urbani et al., 2008). [Pg.131]


See other pages where PECAM is mentioned: [Pg.529]    [Pg.529]    [Pg.530]    [Pg.327]    [Pg.327]    [Pg.329]    [Pg.120]    [Pg.18]    [Pg.82]    [Pg.83]    [Pg.172]    [Pg.411]    [Pg.238]    [Pg.407]    [Pg.20]    [Pg.143]    [Pg.129]    [Pg.551]    [Pg.249]    [Pg.596]    [Pg.128]    [Pg.163]    [Pg.238]    [Pg.13]    [Pg.21]    [Pg.32]   
See also in sourсe #XX -- [ Pg.529 , Pg.529 ]

See also in sourсe #XX -- [ Pg.9 , Pg.17 ]

See also in sourсe #XX -- [ Pg.9 , Pg.17 ]




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Anti-PECAM

Platelet-endothelial cell adhesion molecule PECAM

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