Atrial tachycardia paroxysmal

The uses of the antiarrhythmic drug are given in the Summaiy Drug Table Antiarrhythmic Drug3. In general these drugp are used to prevent and treat cardiac arrhythmias, such as premature ventricular contractions (PVCs), ventricular tachycardia (VT), premature atrial contractions (PACs), paroxysmal atrial tachycardia (PAT), atrial fibrillation, and atrial flutter. Some of the antiarrhythmic dru are used for other... 

In a patient who has had attacks of paroxysmal atrial tachycardia, an ideal prophylactic drug is... 

Cardiovascular manifestations include hypertension and cardiac arrhythmias (e.g., heart block, atrial flutter, paroxysmal atrial tachycardia, ventricular fibrillation, and digitalis-induced arrhythmias). In severe hypokalemia (serum concentration <2.5 mEq/L), ECG effects include ST-segment depression or flattening, T-wave inversion, and U-wave elevation. 

Procainamide is intended for treating paroxysmal atrial tachycardia, atrial fibrillation, prematnre ventricular contraction, and ventricnlar tachycardia. For qnickly reaching therapeutic concentrations, parentemal introdnction of procainamide is preferred over cynidine. Synonyms of this drng are amidoprocaine, cardiorythmine, novocainamide, pronestyl, and others. 

PABA para-amino benzoic acid PAT paroxysmal atrial tachycardia pc after eating (Latin post cibum )... 

The clinical uses of these drugs are associated with their potent vasoconstrictor action. They are used to restore or maintain blood pressure during spinal anesthesia and certain other hypotensive states. The reflex bradycardia induced by their rapid intravenous injection has been used to terminate attacks of paroxysmal atrial tachycardia. Phenylephrine is commonly used as a nasal decongestant, although occasional nasal mucosal... 

Procainamide is an effective antiarrhythmic agent when given in sufficient doses at relatively short (3-4 hours) dosage intervals. Procainamide is useful in the treatment of premature atrial contractions, paroxysmal atrial tachycardia, and atrial fibrillation of recent onset. Procainamide is only moderately effective in converting atrial flutter or chronic atrial fibrillation to sinus rhythm, although it has... 

Rapid loading dose for the management and treatment of CHF control ofventricular rate In patients with atrial fibrillation-, treatment and prevention of recurrent paroxysmal atrial tachycardia PO Initially, 0.5-0.75 mg, additional doses of 0.125-0.375 mg at 6-to8-hr intervals. Range 0.75-1.25 mg. IV 0.6-1 mg. 

Maintenance dosage for CHF control of ventricular rate in patients with atrial fibrillation treatment and prevention of recurrent paroxysmal atrial tachycardia PO, IV... 

Maintenance of normal sinus rhythm after conversion of atrial fibrillation or flutter, prevention of premature atrial, AV, and ventricular contractions paroxysmal atrial tachycardia paroxysmal AV functional rhythm atrial fibrillation atrial flatter paroxysmal ventricular tachycardia not associated with complete heart block PO 100-600 mg q4-6h. (Long-acting) 324-972 mg q8-12h. IV 200-400 mg. 

A healthy 32-year-old doctor, who smoked marijuana 1-2 times a month, had paroxysmal tachycardia for several months. An electrocardiogram was normal and a Holter recording showed sinus rhythm with isolated supraventricular extra beats. He was treated with propranolol. He later secretly smoked marijuana while undergoing another Holter recording, which showed numerous episodes of paroxysmal atrial tachycardia and atrial fibrillation lasting up to 2 minutes. He abstained from marijuana for 12 months and maintained stable sinus rhythm. 

Paroxysmal atrial tachycardia with Wenckebach (Mobitz type I) atrioventricular block has been reported in a patient with a serum digoxin concentration of 3.2 ng/ml (39) and in a patient who in error took three times the recommended dose (40). 

Lown B, Wyatt NF, Levine HD. Paroxysmal atrial tachycardia with block. Circulation 1960 21 129-43. 

A 73-year-old woman taking propafenone 150 mg tds for paroxysmal atrial tachycardia underwent cardioversion during an attack, and the dose of propafenone was increased to 300 mg tds. After 5 days she developed severe ataxia and progressive weakness. The ataxia was symmetrical and there was severe impairment of gait, altered hand coordination, and tremor. The dose of propafenone was reduced to 600 mg/day and the ataxia resolved completely within 6 days. A year later, when the dose of propafenone was increased to 900 mg/day, progressive ataxia again developed after 2 days and became severe within 1 week. Propafenone was withdrawn and the ataxia resolved within a few days. 

Clinical uses PVC, paroxysmal atrial tachycardia, AF, VT Documented life-threatening ventricular arrhythmias. Flecainide also may be used for AF and supraventricular tachycardias in patients without structural heart disease. Propafenone is also indicated for paroxysmal AF. 

Quinidine is used to treat and control atrial fibrillation and atrial flutter. Quinidine is also approved to treat premature ventricular contractions and to treat paroxysmal atrial tachycardia or paroxysmal atrioventricular junctional rhythm. It may also be used to treat malaria, although quinine is preferred. 

Procainamide, proprietary name Pronestyl, is used for therapy of PVCs, ventricular tachycardia, atrial fibrillation, and paroxysmal atrial tachycardia. Its mechanism of action is similar to that of quinidine in that it increases the threshold membrane potential by blocking potassium outflow, reducing excitability and contraction velocity in Purkinje s fibers and ventricular muscle. 

First degree, second degree (Mobitz type I), third degree AV junctional escape rhythms, junctional tachycardia Atrial arrhythmias with slowed AV conduction or AV block Particularly paroxysmal atrial tachycardia with AV block Sinus bradycardia... 

Methoxamine (a,) use in paroxysmal atrial tachycardia—elicits vagal reflex. 

Clinical electrophysiologic studies indicate that verapamil is effective in combating supraventricular arrythmias including atrial premature depolarizations, paroxysmal atrial tachycardia, AV nodal re-entrant paroxysmal supraventricular tachycardia, atrial fibrillation and atrial flutter (154) Verapamil is also potentially beneficial in eliminating... 

Paroxysmal atrial tachycardia occurs with a sudden onset of 140-220 beats/minute, which may cease abruptly. The focus is ectopic—it can be anywhere in the atrium. 

Given intravenously, phenylephrine is useful in the therapy of paroxysmal atrial tachycardia (PAT), or as a pressor agent in hypotensive states. Used topically, it reduces blood vessel diameter and thus is useful as a decongestant, hemostatic agent, or to reduce swelling of inflamed tissues, or as a mydriatic. It is also used systemically in the therapy of frequent urination. 

Which calcium channel blocker is most effective in the therapy of paroxysmal atrial tachycardia ... 

Adenosine is a potent vasodilator that is produced endogenously. It mediates an outward flow of potassium from adenosine-sensitive potassium channels, stabilizing cardiac membranes. This results in a decrease in the duration of the atrial action potential, as well as negative chronotropic and inotropic actions. In addition, by stabilizing excitable tissue in the AV node, the drug effectively inhibits the conversion of paroxysmal atrial tachycardia to ventricular tachycardia, which could lead to fibrillation. 

Metaraminol (aramine) is a mixed-acting agent an agonist at vascular a adrenergic receptors and an indirectly acting agent that stimulates the release ofNE. The drug has been used in the treatment of hypotensive states or off-label to relieve attacks of paroxysmal atrial tachycardia, particularly those associated with hypotension (see Chapter 34 for preferable treatments of this arrhythmia). 

Methoxamine paroxysmal atrial tachycardia through vagal reflex... 

---