Premature ventricular contraction

Cardiac-changes in pulse rate or rhythm electrocardiographic changes, such as bradycardia, tachycardia, premature ventricular contractions, bigeminal (two beats followed by a pause), or trigeminal (three beats followed by a pause) pulse. Other arrhythmias (abnormal heart rhythms)also may be seen. 

The uses of the antiarrhythmic drug are given in the Summaiy Drug Table Antiarrhythmic Drug3. In general these drugp are used to prevent and treat cardiac arrhythmias, such as premature ventricular contractions (PVCs), ventricular tachycardia (VT), premature atrial contractions (PACs), paroxysmal atrial tachycardia (PAT), atrial fibrillation, and atrial flutter. Some of the antiarrhythmic dru are used for other... 

ECG normal sinus rhythm, PR 0.16 s, QRS 0.08 s, QTC 0.38 s, occasional polymorphic premature ventricular contractions, 3 mm ST-segment elevation anterior leads... 

Premature ventricular complexes, 5 88—89 Premature ventricular contractions, 5 108 Premetallized dyes, 9 215-216, 399-401 29 758-759... 

Exposure at 500,000 ppm induced narcosis in rhesus monkeys within 1 min (Shulman and Sadove 1967). Respiratory depression accompanied by multiple premature ventricular contractions occurred when concentrations exceeded 60%. Blood pressure was said to be increased, but the actual data were not reported. 

In an undated study, HCFC-141b was administered to male SpragueDawley rats at concentrations of 5,000, 10,000, or 20,000 ppm for 30 min (Eger, unpublished data). As exposure continued, bolus intravenous epinephrine, characterized as three times the dose that produced arrhythmias in the same rats anesthetized with halothane, was administered. The dose of epinephrine was defined as a maximum of 12 fig/kg. For this study, three or more premature ventricular contractions was considered an arrhythmic response (Table 4—5). Marked arrhythmias occurred at all concentrations. The author further compared the concentrations of halothane and HCFC-141b that produced arrhythmias with administration of various doses of exogenous epinephrine. The nominal chamber concentration for HCFC-141b did not differ from that of halothane. Furthermore, the arrhythmias were characterized as relatively mild and within acceptable limits for surgical anesthesia in humans. 

Ventricuiar proarrhythmic effects in patients with atriai fibriiiation/fiutter Flecainide is not recommended for use in patients with chronic atrial fibrillation. Case reports of ventricular proarrhythmic effects in patients treated with flecainide for atrial fibrillation/flutter have included increased premature ventricular contractions (PVCs), ventricular tachycardia (VT), ventricular fibrillation (VF), and death. 

Premature ventricular contractions (PVCs) During conversion or marked reduction in ventricular rate, benign complexes of unusual appearance (sometimes resembling PVCs) may occur after IV verapamil. 

Genera/-Arrhythmias changes in AV conduction ECG changes (most frequently with toxic doses) flushing heart block hot flushes hypertension hypotension orthostatic hypotension palpitations precipitation of CHF premature ventricular contractions stroke sudden death syncope tachycardia. 

PTCA percutaneous transluminal coronary angioplasty PTH parathyroid hormone PTT partial thromboplastin time PUD peptic ulcer disease pulm pulmonary PVC premature ventricular contraction... 

The indications for use of disopyramide are similar to those for quinidine, except that it is not approved for use in the prophylaxis of atrial flutter or atrial hbrUla-tion after DC conversion. The indications are as follows unifocal premature (ectopic) ventricular contractions, premature (ectopic) ventricular contractions of multifocal origin, paired premature ventricular contractions (couplets), and episodes of ventricular tachycardia. Persistent ventricular tachycardia is usually treated with DC conversion. 

Disopyramide Premature ventricular contractions Atrial arrhythmias, episodic ventricular tachycardia... 

Mexiletine Premature ventricular contractions Ventricular tachycardia... 

Procainamide Atrial tachycardia, ventricular tachycardia Premature ventricular contractions... 

Inappropriate use of oxytocin can lead to uterine rupture, anaphylactoid and other allergic reactions, and possibly maternal death. Prolonged stimulation of uterine contractions can result in the following fetal adverse reactions persistent uteroplacental insufficiency, sinus bradycardia, premature ventricular contractions, other arrhythmias, and fetal death. Prolonged use of oxytocin can lead to water intoxication secondary to the antidiuretic hormone-like effects of oxytocin. Maternal and fetal cardiovascular parameters should be monitored during oxytocin administration. 

Pus. A liquid inflammation product composed made up of cells (leukocytes) and a thin protein-rich fluid called liquor puris. PVC. Pulmonary venous congestion premature ventricular contraction. 

I Unlabeled Uses Angina pectoris, premature ventricular contractions, supraventricular arrhythmias... 

Overdose may produce a marked increase in heart rate (by 30 beats/min or higher), marked increase in BP (by 50 mm Hg or higher), anginal pain, and premature ventricular contractions (PVCs). 

Unlabeled Uses Atrial arrhythmias, complete and nonsustained ventricular arrhythmias, premature ventricular contractions (PVCs)... 

Cardiotoxic effecfs occur mosf commonly with IV administration, particularly at high concentrations, and are observed as conduction changes (50% widening of QRS complex, prolonged QT inferval, flattened T waves, and disappearance of P wave), ventricular tachycardia or flutter, frequent premature ventricular contractions (PVCs), or complete AV block. 

Flecainide is very effective in suppressing premature ventricular contractions. However, it may cause severe exacerbation of arrhythmia even when normal doses are administered to patients with preexisting ventricular tachyarrhythmias and those with a previous myocardial... 

During arrhythmias Atrial tachycardia, atrial fibrillation AV nodal tachycardia, AV blockade Premature ventricular contractions, bigeminy, ventricular tachycardia, ventricular fibrillation... 

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