Oxygen-glucose deprivation

The main finding of the present manuscript is that pharmacological inhibition of the GPx activity, reduces the extent of ischemic damage produced by transient MCAo in the rat brain and limits the irreversible functional derangement of field potentials in corticostriatal slices caused by a prolonged (12 min) oxygen-glucose deprivation. 

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Brain ischemia with mixed cortical cell cultures benzamid, 6(5H)-fenantridinon, 6s 3,4-dihidro-5- I4-1(1-piperidinil) buthoxi)-1(2H) -isoquinolinon Oxygen-glucose deprivation (OGD) 65... 

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Konrath, E. L., Santin, K., Nassif, M., Latini, A., Hemiques, A., Salbego, C. (2008). Antioxidant and pro-oxidant properties of boldine on hippocampal slices exposed to oxygen -glucose deprivation in vitro. Neurotoxicology, 29(6), 1136-1140. 

Zeiger SLH, McKenzie JR, Stankowski JN, Martin JA, CUffel DE, McLaughlin B (2010) Neuron specific metabolic adaptations following multi-day exposures to oxygen glucose deprivation. Biochimica et Biophysica Acta Mol Basis Dis 1802 1095-1104... 

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