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Neuronal injury

Toxic effects often disappear after the cessation of the exposure, but they can also be permanent. The tissue s ability to regenerate is one of the most important factors that determines the nature of toxic effects. For example, liver tissue has a remarkable capacity to regenerate, and therefore liver injur> is often reversible. On the other hand, neuronal cells do not regenerate at all, thus neuronal injury is irreversible. It is true that neuronal cells can compensate for possible losses, but only to a minor degree. In particular, chronic effects tend to be irreversible. ... [Pg.276]

Use cognition disorders therapeutic, antagonist to narcotics, neuronal injury inhibitor... [Pg.1390]

Ellis R, Langford D, MasUah E (2007) HIV and antiretroviral therapy in the brain neuronal injury and repair. Nat Rev Neurosci 8(1) 33 4... [Pg.23]

Lentz MR, Westmoreland SV, Lee V, Ratal EM, Halpem EF, Gonzalez RG (2008) Metabolic markers of neuronal injury correlate with SIV CNS disease severity and inoculum in the macaque model of neuroAlDS. Magn Reson Med 59(3) 475-484 Letendre SL, Lanier ER, McCutchan JA (1999) Cerebrospinal fluid beta chemokine concentrations in neurocognitively impaired individuals infected with human immunodeficiency virus type 1. J Infect Dis 180(2) 310-319... [Pg.27]

Magnetic resonance spectroscopy reveals that activated monocytes contribute to neuronal injury in SIV neuroAIDS. J Clin Invest 115(9) 2534-2545... [Pg.31]

Zhu Y, Jones G et al (2005) Lentivirus infection causes neuroinflammation and neuronal injury in dorsal root ganglia pathogenic effects of STAT-1 and inducible nitric oxide synthase. J Immunol 175(2) 1118-1126... [Pg.86]

Persidsky Y, Zheng J, Miller D, Gendelman HE (2000) Mononuclear phagocytes mediate blood-brain barrier compromise and neuronal injury during HIV-l-associated dementia. J Leukoc Biol 68 413 22... [Pg.143]

Johnston JB, SUva C, Power C (2002) Envelope gene-mediated neurovirulence in feline immunodeficiency virus infection induction of matrix metalloproteinases and neuronal injury. J Virol 76 2622-2633... [Pg.168]

Kaul M, Garden GA, Lipton SA (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410 988-994... [Pg.168]

Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R, Kitazawa S, Miyachi H, Maeda S, Egashira K, Kasuga M (2006) MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Qin Invest 116 1494-1505 Kaul M, Garden GA, Lipton SA (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410 988-994... [Pg.216]

Opioids, Astroglial Chemokines, Microglial Reactivity, and Neuronal Injury in HIV-1 Encephalitis... [Pg.353]

Bruce-Keller AJ, El-Hage N, Knapp PE, Hauser KF (2008) Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HlV-1 tat transgenic mice. Glia 56 1414-1427... [Pg.367]


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See also in sourсe #XX -- [ Pg.25 ]

See also in sourсe #XX -- [ Pg.252 ]

See also in sourсe #XX -- [ Pg.236 , Pg.240 ]




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