Olfactory System Damage

Biomarkers of nickel exposure and effects include nickel concentrations in feces and urine and changes in serum antibodies and serum proteins. Levels of camosine, a dipeptide, seem to reflect the extent of nickel-induced damage to olfactory mucosa of rats, although the rodent olfactory system is more resilient than is the human. Studies on the availability of trace levels of nickel in food and water and in air would be helpful to... 

DOT CLASSIFICATION 2.3 Label Poison Gas, Flammable Gas SAFETY PROFILE A poison by subcutaneous and possibly other routes. Moderately toxic by inhalation. Human systemic effects by inhalation damage to the olfactory nerves and irritation of the conjunctiva. A systemic irritant by inhalation and subcutaneous routes. A human eye... 

SAFETY PROFILE Poison by intravenous route. Moderately toxic by ingestion, subcutaneous, and intramuscular routes. Mildly toxic by skin contact. Human systemic effects by inhalation conjunctiva irritation and changes in the olfactory and respiratory systems. Has caused damage to kidneys, liver, and blood vessels in experimental animals. Experimental reproductive effects. Human mutation data reported. A severe eye irritant. Narcotic-like action. Flammable when exposed to heat or... 

CHRONIC HEALTH RISKS damage to kidneys and liver injury to the vascular system changes in olfactory and respiratory systems may alter genetic material. 

In a correctly operating system, ozone can be detected by smell when the chamber is opened. The smell is similar to that of the air after a lightning storm and indicates that the ozone concentration is less than lOppmbv. Higher concentrations of ozone deaden the olfactory nerves and are harmful. The UV can also cause skin cancer and eye damage so the UV/O3 cabinets should be constructed so that the UV lamp is turned off when the cabinet is opened. The OSHA has set a limit of lOOppbv in the air over an eight hour day, six days per week. At these levels, some irritation and discomfort will be noted by some people. A level of lOppbv is more reasonable. UV/CI2 has been used to clean silicon surfaces but the activated chlorine will rapidly attack staiifless steel surfaces. ... 

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