Numbering system

To identify the main parts of the plant and equipment, a numbering system is used based on the ABC Pharmaceutical Equipment Code. 

The purpose of a numbering system for the documentation is to ensure an unambiguous identification of each validation/qualification document produced within the field of application of the Validation Master Plan. The document number is a combination of letters and numbers with a length of 10 or 11 characters. An example of such a document number might be  

The letters in the first and second positions represent the area that is covered by the document (e.g., qualification of rooms or validation of liquids). A legend for the first two letters is given below  

Liquid dosage forms Creams/ointments/ suppositories Solid dosage forms Cleaning 

The next three positions represent a serial number for the document. This number should be assigned according to the chronological order of documentation development. 

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The numbering system of tetracyclines is used for synthetic intennediates. 

Cyclic compounds that contain at least one atom other than carbon within their ring are called heterocyclic compounds, and those that possess aromatic stability are called het erocyclic aromatic compounds Some representative heterocyclic aromatic compounds are pyridine pyrrole furan and thiophene The structures and the lUPAC numbering system used m naming their derivatives are shown In their stability and chemical behav lor all these compounds resemble benzene more than they resemble alkenes... 

Here, the Wilson numbering system is being used, which is frequently used for benzene (see the bibliography). 

The Stock Oxidation-Number System. Stock sought to correct many nomenclature difficulties by introducing Roman numerals in parentheses to indicate the state(s) of oxidation, eg, titanium(II) chloride for TiCl2, iron(II) oxide for FeO, titanium(III) chloride for TiCl, iron(III) oxide for Fe203, titanium(IV) chloride for TiCl, and iron(II,III) oxide for Fe O. In this system, only the termination -ate is used for anions, followed by Roman numerals in parentheses. Examples are potassium manganate(IV) for K2Mn02, potassium tetrachloroplatinate(II) for K PtCl, and sodium hexacyanoferrate(III) for Na3Fe(CN)3. Thus a set of prefixes and terminations becomes uimecessary. 

The oxidation-number system is easily extended to include other coordination compounds. Even the interesting substances represented by the formulas Na4Ni(CN)4 and K4Pd(CN)4 create no nomenclature problem they become sodium tetracyanonickelate(0) and potassium tetracyanopaHadate(0), respectively. 

Implicit ia the base names are the absolute configurations at carbons 8 and 12 and the iadicated numbering systems. Derivatives of these parent stmctures are named according to terpene and steroid nomenclature rules (see Steroids Terpenoids). The lengthy and awkward nature of the chemical abstract systematic nomenclature (12) for these compounds has resulted ia the development (13) and use of simplified nomenclature based on common names. 

Table 9 shows the classification system for blacks most commonly used in mbber. The ASTM numbering system is based on the fundamental particle si2e of the black. Particle si2e is deterrnined by several methods, including iodine absorption, nitrogen absorption, and light scattering. 

The standard AISI types with the Unified Numbering System (UNS) designation are identified in Table 4. A number of proprietary types have not been Hsted. These are for specific uses, which justify their substantial cost. 

The stmcture of vitamin A [11103-57-4] and some of the important derivatives are shown in Figure 1. The parent stmcture is aH-Zra/ j -retinol [68-26-8] and its lUPAC name is (all-E)-3,7-dimethyl-9-(2,6,6-trimethyl-l-cyclohexen-l-yl)-2,4,6,8-nonatetraen-l-ol (1). The numbering system for vitamin A derivatives parallels the system used for the carotenoids. In older Hterature, vitamin A compounds are named as derivatives of trimethyl cyclohexene and the side chain is named as a substituent. For retinoic acid derivatives, the carboxyl group is denoted as C-1 and the trimethyl cyclohexane ring as a substituent on C-9. The stmctures of vitamin A and -carotene were elucidated by Karrer in 1930 and several derivatives of the vitamin were prepared by this group (5,6). In 1935, Wald isolated a substance found in the visual pigments of the eye and was able to show that this material was identical with Karrer s retinaldehyde [116-31-4] (5) (7). 

A classification based first on ion specificity, then on stmctural features has been suggested for the polyethers (7). Another method uses the presence of unsaturation or of aromatic groups in the molecular skeleton (8). In this review the compounds are classified based on the number of carbons in the backbone according to the numbering system proposed in reference 9. The carbon backbone or skeleton refers to the longest chain of contiguous carbons between the carboxyl group and the terminal carbon. 

J. B. Casey, W. J. Evans, W. H. PoweU, and T. E. Sloan, "A Stmctural Definitive Descriptor and Numbering System for Cluster Compound Nomenclature," Chemical Abstract Service, presented at the 198th National Meeting of the American Chemical Society, Miami Beach, FI., Sept. 1989. 

Unified Numbering System Ref. 49. American Iron and Steel Institute. ... 

Table 18. Basic Numbering System for Chromium-Bearing Low Alloy Steels...

UNS is the United Numberiug System. The XX after the grade designation foUows the AISI/SAE system and hence iadicates carbon content the Z is either an arbitrary number or 0. Eor a hiUer description and tabulations of this new numbering system, see reference 49. 

Enified Numbering System for Metals and Alloys, SAE HE 1086 or ASTM DS-56A, 5th ed., 1989 Also available in electronic form on floppy disk. 

The nominal chemical composition and identification of the most important copper castiag alloys are Hsted ia Table 7. These alloys are ideatifted by name and by the Unified Numbering System. The use of names is not recommended. 

Unified Numbering System for Metals andMlloys, SAE HS 1086a or ASTM DS-56a, 2nd ed., 1977. 

The Chemical Abstracts numbering system of phenazine is used. 

This is not the normal numbering system for these molecules. 

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