Nervous system nerve

Peripheral nervous system Nerve tissues lying outside the brain and spinal cord, functions include the transmittal of sensory information such as touch, heat, cold, and pain, and the motor impulses for limb movement. 

NK3rs are preferentially expressed in the CNS. At the peripheral level, NK3rs have been localized in the enteric nervous system, nerve terminals, and autonomic ganglia, but also on other tissues. At the peripheral level, it remains to be explained the mismatch between NK3r expression and the apparent lack of expression of NKB there are, however, physiological conditions... 

Ecstasy also stimulates the sympathetic nervous system (nerves located outside the brain and spinal cord), causing increases in heart rate and blood pressure. 

Neurotoxicity Cells of the central nervous system, CNS (brain and spinal cord) and the peripheral nervous system (nerves outside the CNS) Neuronopathies (neuron injury) Axonopathies (axon injury) Demyelination (loss of axon insulation) Interference with neurotransmission... 

Central nervous system nerve cell receptors... 

Nervous system abnormalities. Balali-Mood et al. (2005) conducted smdies on peripheral neuropathic processes in victims exhibiting severe late manifestations of mustard poisoning using electromyography and nerve conduction velocity. Seventy percent of the patients demonstrated disturbances in the peripheral nervous system. Nerve conduction abnormalities were more common in sensory nerves and more prevalent in lower extremities than in upper extremities. Forty percent of the patients exhibited incomplete interference patterns in electromyographic studies. 

Damage of the central nervous system (nerves of spinal cord) can be caused by disease or trauma and often results in paralysis, which at present can not be cured. Every year, more than 11,000 individuals sustain spinal injury in the USA. These are mostly young men, median age 26. Of the quarter of a million people living in the USA after spinal cord injury, nearly half have irreversible loss of neurologic function below the level of injury (with either lower limbs or all four limbs paralyzed). (Madigan et al., 2009). It is known, that in Europe it is comparable number but complete data is not available. The aim of a lot researches is to pave the way for reversing this loss of neurologic functions, which is still perceived as irreversible . 

Alzheimer s disease Nervous system nerve growth factor... 

Nervous System Nerve Membrane Chemical to Electrical... 

Mode of Motion. Nicotine, anabasine, and imidocloprid affect the ganglia of the insect central nervous system, faciUtating transsynaptic conduction at low concentrations and blocking conduction at higher levels. The extent of ionisation of the nicotinoids plays an important role in both their penetration through the ionic barrier of the nerve sheath to the site of action and in their interaction with the site of action, which is befleved to be the acetylcholine receptor protein. There is a marked similarity in dimensions between acetylcholine and the nicotinium ion. 

Mode of Motion. The cyclodienes, like lindane and toxaphene, affect the nerve axon produciag hyperactivity, convulsions, prostration, and death. The biochemical lesion is the competitive inhibition of the y-aminobutyric acid (GABA) neurotransmitter binding site of the nerve axon. Spray workers with lengthy exposure to dieldrin have suffered from prolonged and repeated central nervous system disturbances produciag epileptiform coavulsioas. Similar disturbances occurred ia workers heavily exposed to chlordecoae. 

Neuropeptide Y. Neuropeptide Y [82785 5-3] (NPY) (255) is a 36-amiao acid peptide that is a member of a peptide family including peptide YY (PYY) [81858-94-8, 106338-42-5] (256) and pancreatic polypeptide (PPY) [59763-91-6] (257). In the periphery, NPY is present in most sympathetic nerve fibers, particulady around blood vessels and also in noradrenergic perivascular and selected parasympathetic nerves (66). Neurons containing NPY-like immunoreactivity ate abundant in the central nervous system, particulady in limbic stmctures. Coexistence with somatostatin and NADPH-diaphorase, an enzyme associated with NO synthesis, is common in the cortex and striatum. 

As a neurotransmitter in the sensory nervous system, high levels of substance P are found in the dorsal horn of the spinal cord as well as in peripheral sensory nerve terminals. However, substance P also plays a significant role as a neuromodulator in the central, sympathetic, and enteric nervous system. NKA and NKB are also localized selectively in the CNS. 

The human body has more than 600 muscles. The body s movement is performed by muscle contractions, which are stimulated by the nervous system. This system links muscle tissue to the spinal cord and brain. The network of nerve cells which carries the brain s signals directs the flow of muscular energy. Most muscular activity occurs beyond the range of the conscious mind. The body, working through the neuromuscular network, manages... 

Choline functions in fat metaboHsm and transmethylation reactions. Acetylcholine functions as a neurotransmitter in certain portions of the nervous system. Acetylcholine is released by a stimulated nerve cell into the synapse and binds to the receptor site on the next nerve cell, causing propagation of the nerve impulse. 

The same author found Z-hyoscine sixteen to eighteen times as active as the d-isomeride in antagonising the action of pilocarpine on the termination of nerves in the salivary glands, -while both isomerides are equally active on nerve ends in striated and unstriated muscle and on the central nervous system. 

Anchusa officinalis L. Cynoglossine B. HCl, crystalline. Paralyses peripheral nerve terminations. Consolidine gluco-alkaloid hydrolysed to glucose and consolicine (also present as such). Paralyses the central nervous system. The same alkaloids are also present in Echium vulgare L. and Cynoglossum offikinale L. (Greiner, Arch. Pharm., 1900, 238, 505). 

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