Nerve conduction

Clinical use Mepivacaine has been employed for all types of infiltration and conduction nerve block anesthesia using solutions of 1.0 and 1.5 % lasting for 1.5 to 3 h. Epidural anesthesia with 2.0 % mepivacaine has a rapid onset with a dense motor block. Hyperbaric solutions of mepivacaine have also been used for spinal anesthesia (Tetzlaff, 2000). Mepivacaine has been used for topical applications, but other LA such as lidocaine are more effective. 

Serotonin is a compound that conducts nerve impulses in the brain. Serotonin is 68.2 percent C, 6.86 percent H, 15.9 percent N, and 9.08 percent O. The molar mass is 176 g/mol. What is the molecular formula of serotonin ... 

One of early manifestations of neuropathy consists in a sharp (by 35 to 40%) reduction in conduction velocity of stimulation along peripheral nerves and a decrease in action potential amplitude of nerve, which are noted prior to the development of other clinical signs (ataxia, paresis, paralysis). The changes observed indicate the loss of excitability firstly by the A-6 thick fast-conducting nerve fibers [34, 36], In the pathogenesis of DNE induced by OPC, there take place an immunopathological component (the development of autoimmune process) [38,39], intensification in lipid peroxidation in neural tissue, labilization of lysosomal membranes, and activation of acid hydrolases [40, 41],... 

P. Moroder, H. Wang, T. Ruesink, L. Lu, A.I. Windebank, M.J. Yaszemski, M.B. Runge, Material properties and electrical stimulation regimes through polycaprolactone fumarate— polypyrrole scaffolds as potential conductive nerve conduits, Acta Biomater. 7 (2011) 944-953. 

M. H. Sherebrin, B.A.E. MacClement, and A. J. Franko, Electric Field-Induced Shifts in the Infrared Spectrum of Conducting Nerve Axons, Biophys. J. 12, 977-989 (1972). 

Function. Myelin serves as an electrical insulator therefore, myelinated nerves conduct nerve impulses faster than nonmyelinated nerves. 

---