Naringin extract

Grapefruit oil (also partially deterpenized) and naringin extract. Oil is official in F.C.C. 

Different extracts of Citrus were subjected to SPE on Cig cartridges to remove polar components. The retained flavonoids (mainly flavanones) were eluted with methanol-dimethyl sulfoxide, which enhanced solubility of hesperidin, diosmin, and diosmetin. Recoveries of eriocitrin, naringin, hesperidin, and tangeretin from spiked samples of mesocarp tissue exceeded 96%. Flavones were relatively abundant in the leaves. ... 

Spices (rosemary, sage, thyme) contain considerable amounts of flavonols and flavones, mainly in the glycoside form (154). Thus, phenolic analyses in spices were often considered in order to determine the optimum time for plant collection to give maximum flavonoid contents and for health benefits (154,155). Flavonoids (naringin, luteolin, apigenin, and chrysoeriol) were extracted from spices using a percolation process at room temperature with solvents (MeOH and EtOAc), and HPLC analysis was carried out (155). 

In the early work on bioflavonoids, citrus extracts were used, and later research has revealed the presence of highly active methoxylated flavones in citrus. The amount of these flavones recovered along with the more abundant hesperidin, naringin, eriodictyol varies with the methods of extraction and purification used. Thus, bioflavonoid preparations by the many workers may have varied widely in activity. 

Extraction and finisher pressures can greatly influence the flavonoid content of citrus juices. Generally, as the fruit is squeezed harder more juice is recovered. However, excessive extractor pressures produce juice of a lower quality (35). As shown in Figure 8, grapefruit flavanone glycoside concentrations increase with increasing extractor pressures. In the early portion of the season almost twice as much naringin was obtained under hard squeeze conditions than was obtained with the soft squeeze. The effect of finisher pressure is not as clear, and is dependent on the composition of the raw juice which, in turn, is dependent on the type of extractor used. 

Citrus juice Narirutin, (neo) eriocitrin (neo) hesperidin, naringin, didymin Freeze-dried, extracted with ether or hexane, followed by EtAc, MeOH or ACN C-18 MeOH-H20-acetic acid HPLC/DAD (280 nm) 7-18 mg/L 11... 

Orange juice, grape juice Naringin, hesperidin, nari rutin Extraction with MeOH, centrifugation, glass fiber filtration C-18... 

Orange, Hesperidin, naringin. Vortex mixing, solvent 1 g sample was extracted with Bronner and... 

No changes in the QT, interval or blood pressure were observed after a single dose of bitter orange fruit concentrated extract (450 mg with 27 mg synephrine) (Min et al. 2005). No increases in systolic or diastolic blood pressure or heart rate occurred in fasting volunteers 45 minutes after oral consumption of bitter orange fruit concentrated extract containing 50 mg p-synephrine with or without the flavo-noids naringin and hesperidin (Stohs et al 2011). 

Neohesperidine dihydrochalcone [VII] is a semisynthetic sweetener prepared from neohesperidin or naringin, two flavanones extracted from citrus peel. In aqueous solutions, neohesperidine dihydrochalcone is stable in the pH range 2.5-3.5. Neohesperidine... 

The flavonoid glycosides hesperidin (60) and naringin (61) (Fig. 11.25) from Citrus natsudaidai stimulated oviposition by Papilio protenor (Honda, 1986). Again, the compounds were inactive alone, but were active when combined with a more polar extract of the plant. 

Diastereomers of four flavinoids (naringin, pnmin, neohesperidin, narirutin) were resolved on a ) -cyclodextrin column (A = 280 nm) using a 20-min 95/5 - 50/50 (90/10/0.5 methanol/water/acetic acid)/(95/5 methanol/water) gradient [371]. Nine flavanoids [372] extracted from Ginkgo biloba leaves (quercetin, apigenin. 

Six flavanone glycosides (eriocitrin, naiirutin, hesperidin, neoeriocitrin, naringin, neohesperidin) were extracted from citrus Juices and resolved on a Cjg column... 

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