Myelomonocytic cells

Li H, Wong WS. Pertussis toxin activates tyrosine kinase signaling cascade in myelomonocytic cells a mechanism for cell adhesion. Biochem Biophys Res Commun 2001 283(5) 1077-1082. 

CYP24 mRNA subject to alternative splicing in human myelomonocytic cell line (Ren et al, 2005). 

Hanjan, S. N. S., Kearney, J. F., and Cooper, M. D. (1982) A monoclonal antibody (MMA) that identifies a differentiation antigen on human myelomonocytic cells. Clin. Immunol. Immunopathol. 23,172. 

Andersson, P. B., Perry, V. H., and Gordon, S., Intracerebral injection of proinflam-matory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system, J. Exp. Med., 176,255, 1992. 

It is our hypothesis9 that fetal macrophages (primitive myelomonocytic cells), which are present in the developing CNS prior to the onset of brain vascularization810... 

Matsushima, K., Larsen, C., DuBois, G., and Oppenheim, J., Purification and characterisation of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line, J. Exp. Med., 169, 1485, 1989. 

CD33 myelomonocytic cells 2 Sia(a2-3)Gal(Pl-3)GalNAc Sia(a2-3)Gal(Pl-3/4)GlcNAc myelomonocytic cells [1031] [1032]... 

Conlan JW, North RJ. Monoclonal antibody NIMP-RIO directed against the CDllb chain of the type 3 complement receptor can substitute for monoclonal antibody 5C6 to exacerbate listeriosis by preventing the focusing of myelomonocytic cells at infectious foci in the liver. J leukocyte Biol 1992 52(1) 130-132. 

Rosen H, Gordon S, North RJ. Exacerbation of murine listeriosis by a monoclonal antibody speciflc for the type 3 complement receptor of myelomonocytic cells. Absence of monocytes at infective foci allows Listeria to multiply in nonphagocytic cells. J Exp Med 1989 170(l) 27-37. 

Scott LM, Civin Cl, Rorth P, Friedman AD A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells. Blood 1992 80 1725-1735. 

Sung SJ, Walters JA, Hudson J, Gimble JM Tumor necrosis factor-a mRNA accumulation in human myelomonocytic cell lines. Role of transcriptional regulation by DNA sequence motifs and mRNA stabilization. J Immunol 1991 147 2047-2054. 

Bertani A, Polentamtti N, Sica A, Rambaldi A, Mantovani A, Colotta F Expression of c-jun protooncogene in human myelomonocytic cells. Blood 1989 74 1811-1816. 

Allan DS, Colonna M, Lanier LL, Churakova TD, Abrams JS, Ellis SA, McMichael AJ. Braud VM (1999) Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells. J Exp Med 189 1149- 1156... 

Colonna M, Navarro F, Bellon T, Llano M, Garcia P, Samaridis J, Angman L, Celia M, Lopez-Botet M (1997) A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J Exp Med 186 1809-1818 Colonna M, Navarro F, Lopez-Botet M (1999) A novel family of inhibitory receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells. Curr Top Microbiol Immunol 244 115-122... 

U-937 cells, a myelomonocytic cell line derived from a patient with histiocytic lymphoma, when differentiated by phorbol myristate acetate and exposed to DQ12 quartz (specific area 3 mVg), Mn02... 

The initial events of the cellular response to LPS have now been characterised endotoxin responses are initiated by the binding of complexes of LPS and LPS-binding protein to CD14, which is a phos-phatidyhnositol-linked surface receptor present mainly in myelomonocytic cells (Schuman et al. 1990, Wright et al. 1990, Ziegler-Heitbrock et al. 1994). Subsequently, activation of these cells oc-... 

Fagan, D. L., Prehn, J. L., Adams, J. S., Jordan, S. C. 1991. The human myelomonocytic cell line U-937 as a model for studying alterations in steroid-induced monokine gene expression Marked enhancement of Upopolysaccharide-stimulated interleukin-1 beta messenger RNA levels by 1,25-dihydroxy vitamin D3. Mol Endocrinol 5 179-86. 

Liu M, Lee M-H, Cohen M, Bommakanti M, Freedman LP (1996) Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Gene Develop 10 142-153... 

Arar, C., V. Carpentier, J. P. Le Caer, M. Monsigny, A. Legrand, and A. C. Roche, ERGIC-53, a membrane protein of the endoplasmic reticulum-Golgi intermediate compartment, is identical to MR60, an intracellular mannose-specific lectin of myelomonocytic cells, J. Biol... 

Ouaaz, F, Sola, B., Issaly, F., Kolb, J.P, Davi, F., Mentz, F., Arock, M., Paul-Eugene, N., Korner, M., Dugas, B., and et al. (1994). Growth arrest and terminal differentiation of leukemic myelomonocytic cells induced through ligation of surface CD23 antigen. Blood 84, 3095-3104. 

Clusters of monocytes/macrophages apparently synthesize eicosanoids like thromboxane (TX) A2 or the peptidoleukotrienes C4, D4, and E4, which promote platelet aggregation and cause vascular constriction [38,71,73,82,88,119] this may explain the reduced blood flow during atherogenesis [74]. Leukocytes produce the potent chemoattractant leukotriene (LT) B4 [73], which promotes leukocyte migration and the intramural deposition of clusters of white blood cells. Infiltration of myelomonocytic cells or activation of tissue-resident macrophages will potentially increase the locally available amount of eicosanoid synthetic enzymes, implying a probably enhanced cellular vulnerability in case of phospholipase activation and arachidonate release. 

In summary, the net result of a diet enriched with fish-oil-derived fatty acids in a potentially inflammatory process appears to be a decrease in the dcosanoid synthesis of myelomonocytic cells, with preferential inhibition of the formation of leukotrienes of the 4-series and a parallel loss of functional competence of these inflammatory cells. 

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