Monokine induced by IFN-y

Dorsey R, Kundu N, Yang Q, Tannenbaum CS, Sun H, Hamilton TA, Fulton AM. Immunotherapy with interleukin-10 depends on the CXC chemokines inducible Protein-10 and Monokine induced by IFN-y. Cancer Res. 62 2606-2610, 2002. 

Alternatively neutrophils may release CXC chemokines. These amplify their ovm recruitment (GROs/CXCL 1-2-3 and IL-8) or promote T and NK cell recruitment (monokine induced by IFN-y, MIG/CXCL9 IP-lO/CXCLlO IFN-inducible T cell a chemoattractant, I-TAC/CXCLl 1) and Th2 immune responses [12],... 

Lauw FN, Simpson AJH, Prins JM, van Deventer SHH, Chaowagul W, White NJ, Van der Poll T. The CXC chemokines ganuna interferon (IFN-yj-inducible protein 10 and monokine induced by IFN-y are released during severe melioidosis. Infect Immun 2000 68 3888-3893. 

Some soluble products are secreted by cells of the immune system other than lymphocytes. For example, monocytes/macrophages are also capable of secreting cytokines, which are sometimes referred to as monokines and which include some interleukins, such as IL-1, IL-6, IL-8, and IL-12, and other factors such as tumor necrosis factor (TNF). Some soluble products with important roles in the immune system originate outside of the immune system. One example is interferon (IFN), which is actually a heterogeneous family of proteins of two types. Type I or viral IFNs are induced by infection and consists of IFN-a (interferon-a) and -IFN-)S, which are secreted by leukocytes, and fibroblasts or epithelial cells, respectively. Type II or immune IFN, consists of IFN-y, which is secreted by T cells (therefore, IFN-y can be classified as a lymphokine) in response to specific antigens. A second example of a soluble product which originates outside of the immune system is complement, which is primarily produced in the liver. Complement is actually a group of 20... 

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