Multisyringe chromatography

However, since HPLC equipment is expensive, a search for more affordable alternatives was fostered, such as sequential injection chromatography (SIC) and multisyringe chromatography (MSC), both performed with a monolithic column, which have proved to be effective alternatives to HPLC. 

M.A. Obando, J.M. Estela, V. Cerda, Multisyringe chromatography (MSC) system for the on-line solid-phase extraction and determination of hydrochlorothiazide and losartan potassium in superficial water, groundwater and wastewater outlet samples, J. Pharm. Biomed. Anal. 48 (2008) 212—217. 

F. Maya, J.M. Estela, V. Cerda, Interfacing on-line solid phase extraction with monolithic column multisyringe chromatography and chemiluminescence detection an effective tool for fast, sensitive and selective determination of thiazide diuretics, Talanta 80 (2010) 1333—1340. 

C. Ferndndez, M.S. Larrechi, R. Forteza, V. Cerda, M.P. Callao, Multisyringe chromatography (MSC) using a monolithic column for the determination of sulphonated azo dyes, Talanta 82 (2010) 137—142. 

C.A. Chavez, J.L. Guzman-Mar, L. Hinojosa-Reyes, A. Hemandez-Ramfrez, L. Ferrer, V. Cerda, Applicability of multisyringe chromatography coupled to on-line solid-phase extraction to the simultaneous determination of dicamba, 2,4-D, and atrazine. Anal Bioanal. Chem. 403 (2012) 2705—2714. 

FIGURE 4.10 Schematic depiction of an multisyringe chromatography system applied to oxalate determination in beer and urine with chemiluminescence detection. HC holding coil KRC knotted reaction coil MC monolithic column—10 mm x 4.6 mm Qg coated with cetyltrimethyl ammonium bromide (CTAB) PMT photomultiplier Rl tris(2,2 -bipyridyl)dichlororuthenium(II) solution R2 cerium(IV) solution S syringe SFC spiral flow cell V three-way solenoid valve and W waste. 

Fernandez, M., R. Forteza, and V. Cerda. 2012. Multisyringe chromatography (MSG) An effective and low cost tool for water-soluble vitamin separation. Anal. Lett. 45 2637-2647. 

J.B. Quintana, M. Miro, J.M. Estela, V. Cerda, Automated on-line renewable solid-phase extraction-liquid chromatography exploiting multisyringe flow injection-bead injection lab-on-valve analysis, Anal. Chem. 78 (2006) 2832. 

H.M. Oliveira, M.A. Segundo, J.L.F.C. Lima, V. Cerda, Multisyringe flow injection system for solid-phase extraction coupled to liquid chromatography using monolithic column for screening of phenolic pollutants, Talanta 77 (2009) 1466. 

Maya, F., J. M. Estela, and V. Cerda. 2011. Multisyringe ion chromatography with chemiluminescence detection for the determination of oxalate in beer and urine. Microchim. Acta 173 33-41. 

Oliveira, H. M., M. A. Segundo, J. L.F.C. Lima et al. 2010. On-line renewable solid-phase extraction hyphenated to liquid chromatography for the determination of UV filters using bead injection and multisyringe-lab-on-valve approach. J. Chromatogr. A 1217 3575-3582. 

Note A amperometry BI bead injection CL chemiluminescence F fluorescence FAT flow analysis technique HPLC/DAD high-performance liquid chromatography with diode array detector LOD detection limit MCFIA multicommutated flow injection analysis MPFS multipumping flow systems MSFIA multisyringe FIA P potentiometry RSD relative standard deviation SF sampling frequency SFA stopped-flow analysis SP spectrophotometry. 

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