Monitoring of actions

The results of the assessment are documented in an Environmental Impact Statement (EIS), which discusses the beneficial and adverse impacts considered to result from the activity. The report is one component of the information upon which the decision maker ultimately makes a choice. A final decision can be made with due regard being paid to the likely consequences of adopting a particular course of action, and where necessary by introducing appropriate monitoring programs. 

During the construction of a ship the Surveyor monitors NDE results for completeness of testing and overall quality of welding. This role includes the evaluation of checkpoints taken specifically for classification purposes but also includes the monitoring of additional checkpoints taken for quality control purposes by the builder. In the case of tankers built to LR Class since 1994 and for bulk carriers built to Class since January 1996 the Surveyor will witness the actions listed as part of the ShipRight Construction Monitoring procedure that is now mandatory. 

The cathodic protection of pipelines is best monitored by an intensive measurement technique according to Section 3.7, by an off potential survey eveiy 3 years and by remote monitoring of pipe/soil potentials. After installation of parallel pipelines, it can be ascertained by intensive measurements whether new damage of the pipe coating has occurred. These measurements provide evidence of possible external actions that can cause mechanical damage. 

Implementation Phase the step in a pollution prevention assessment where procedures, training, and equipment changes are put into action to reduce waste. IMPROVE Interagency Monitoring of Protected Visual Environments, a collaborative monitoring program to establish present visibility levels and trends, and to identify sources of man-made impairment. 

These eiTors occur, not in spite of the fact that someone is well-trained but because he or she is well-trained. Routine operations are relegated to the lower levels of the brain and are not continuously monitored by tbe conscious mind. We would never get through the day if everything we did required our full attention. When the normal pattern or program of actions is interrupted for any reason, errors are likely to occur. These slips are very similar to those we make in everyday life. Reason and Mycielska [1] have described the psychology of such slips. 

Ironically, many errors occur because a person is well trained. Routine operations are controlled by lower levels of the brain and are not continuously monitored by the conscious mind. When tlie normal pattern of action is interrupted, an error is more likely to occur. 

Figure 2.16 Clirotnatograms of a pentane extract of a water sample containing 200 ppb of a naphtha fraction (a) sample extracted by using a continuous flow system, where a pressurized bottle was employed as the sample-delivery system (b) batch-extracted sample. Reprinted from Journal of Chromatography, A 330, J. Roeraade, Automated monitoring of organic Race components in water. I. Continuous flow exti action together with on-line capillary gas cliro-matography , pp. 263 - 274, copyrigth 1985, with permission from Elsevier Science.

The purpose of predictive maintenance is to minimize unscheduled equipment failures, maintenance costs and lost production. It is also intended to improve the production efficiency and product quality in the plant. This is accomplished by regular monitoring of the mechanical condition, machine and process efficiencies and other parameters that define the operating condition of the plant. Using the data acquired from critical plant equipment, incipient problems are identified and corrective actions taken to improve the reliability, availability and productivity of the plant. 

Hirsh J, Warkentin TE, Shaughnessy SG et al (2001) Heparin and low-molecular-weight heparin mechanisms of action, pharmacokinetics, dosing, monitoring, efficacy, and safety. Chest 119(Suppl.) 64S-94S... 

To evaluate die patient s response to tiierapy, and depending on die drug administered, die nurse may check die patient s blood pressure every hour, inquire whether pain has been relieved, or monitor die pulse every 15 minutes. After evaluation, certain otiier decisions may need to be made and plans of action implemented. For example, die nurse may need to notify die primary health care provider of a marked change in a patient s pulse and respiratory rate after a drug was administered, or die nurse may need to change die bed linen because sweating occurred after a drug used to lower die patient s elevated temperature was administered. 

A crucial issue for antiviral therapy is the fact that all antiviral substances rapidly select for resistance thus, monitoring and overcoming resistance has become a most important clinical paradigm of antiviral therapy. This calls for cautious use of antiviral drugs and implementation of combination therapies. In parallel, efforts in drug discovery have to be continued to develop compounds with novel mode-of-action and activity against resistant strains. This book reviews the current status of antiviral therapy, from the roads to development of new compounds to their clinical use and cost effectiveness. Individual chapters address in more detail all available drug classes and outline new approaches currently under development. 

Some biomarker responses provide evidence only of exposure and do not give any reliable measure of toxic effect. Other biomarkers, however, provide a measure of toxic effects, and these will be referred to as mechanistic biomarkers. Ideally, biomarker assays of this latter type monitor the primary interaction between a chemical and its site of action. However, other biomarkers operating down stream from the original toxic lesion also provide a measure of toxic action (see Figure 14.3 in Chapter 14), as, for instance, in the case of changes in the transmission of action potential... 

Heparin and warfarin are widely used in the treatment of thrombotic and thromboembolic conditions, such as deep vein thrombosis and pulmonary embolus. Heparin is administered first, because of its prompt onset of action, whereas warfarin takes several days to reach full effect. Their effects are closely monitored by use of appropriate tests of coagulation (see below) because of the risk of producing hemorrhage. 

Best course of action is 3 above. You could monitor the situation to check that it gets fixed. 

Figure 1.9 Comparison of the effects of an endogenously released and exogenously applied neurotransmitter on neuronal activity (identity of action). Recordings are made either of neuronal firing (extracellularly, A) or of membrane potential (intracellularly, B). The proposed transmitter is applied by iontophoresis, although in a brain slice preparation it can be added to the bathing medium. In this instance the applied neurotransmitter produces an inhibition, like that of nerve stimulation, as monitored by both recordings and both are affected similarly by the antagonist. The applied neurotransmitter thus behaves like and is probably identical to that released from the nerve...

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