Metrics leading

Several issues, however, need further exploration. While considerable efforts have been made in developing performance metrics, leading metrics such as management metrics still require additional development. Such metrics, however, may differ considerably from one company or organization to another due to the varying cause-and-effect relationship within each company or organization. Moreover, while anecdotal evidence exists that links various impacts to a company s financial performance, further studies are needed to more explicitly link sustainability metrics to a company s exposure to risks and opportunities. 

Library metrics lead us to believe that only certain classes of compounds can ever be seriously considered as potentially becoming drugs. Druglikeness, novelty, and diversity can become such awful mantras that we will miss the blue sky quantum leaps into new drug types. Even today, there is still room in the screening programs of some companies for compounds that are quite remote from the metric-designed library. 

The search for such maintenaace metrics leads inexorably to RAMS parameters which constitute a small and easily quantifiable parameter of the state of machinery, Mora (2002), and subsequent establishment of measurable objectives. 

Three types of process safety performance metrics are described in the document and the text on their selection and application is extensive. Reference is made to lagging metrics leading metrics, and near miss and other internal lagging metrics. Note that near misses are a metric separate from lagging indicators. This is the only publication found that makes that disfinction. As will be seen, there is a purpose for doing so in the CCPS document. The metrics pertain only to chemical process incidents and near misses, to the exclusion of types of incidents that are not process related. 

The objective of any organization is to continue to expand the focus on process metrics (leading indicators) as the primary means of measuring the safety management system performance (i.e., loss-producing events are not the only measurement). 

A situation that arises from the intramolecular dynamics of A and completely distinct from apparent non-RRKM behaviour is intrinsic non-RRKM behaviour [9], By this, it is meant that A has a non-random P(t) even if the internal vibrational states of A are prepared randomly. This situation arises when transitions between individual molecular vibrational/rotational states are slower than transitions leading to products. As a result, the vibrational states do not have equal dissociation probabilities. In tenns of classical phase space dynamics, slow transitions between the states occur when the reactant phase space is metrically decomposable [13,14] on the timescale of the imimolecular reaction and there is at least one bottleneck [9] in the molecular phase space other than the one defining the transition state. An intrinsic non-RRKM molecule decays non-exponentially with a time-dependent unimolecular rate constant or exponentially with a rate constant different from that of RRKM theory. 

Applications. The principal use for rigid polyurethane foams is for iasulation ia various forms utilized by a variety of iadustries. Lamiaates for resideatial sheatiag (1.2 to 2.5 cm thick with aluminum skins) and roofing board (2.5 to 10.0 cm thick with roofing paper skins) are the leading products with about 45 metric tons of Hquid spray systems also ia use. Metal doors iasulated by a pour-ia-place process coastitute another substantial use. 

Lead [7439-92-17, Pb, is an essential commodity ia the modem iadusttial world, ranking fifth ia tonnage consumed after iron (qv), copper (qv), aluminum (see Aluminumand aluminum alloys), and 2iac (see Zinc and zinc alloys). In 1993, the United States accounted for 30% of the 4,450,000 metric tons of refined lead consumed by the Western world. Slightly over half of the lead produced ia the world now comes from recycled sources (see Recycling, NONFERROUS LffiTALS). 

Use of lead ia modem iadusttial society results from its unique physical and chemical properties. By the middle of the nineteenth century, world production of lead had risen to 1 x 10 metric tons per year, passed 1 x 10 t /yr early in the twentieth century, and reached 1.5 x 10 t /yr by midcentury. Lead production is expected to reach 5.6 x 10 t/yr by the year 2000. 

Deposits. Selenium forms natural compounds with 16 other elements. It is a main constituent of 39 mineral species and a minor component of 37 others, chiefly sulfides. The minerals are finely disseminated and do not form a selenium ore. Because there are no deposits that can be worked for selenium recovery alone, there are no mine reserves. Nevertheless, the 1995 world reserves, chiefly in nonferrous metals sulfide deposits, are ca 70,000 metric tons and total resources are ca 130,000 t (24). The principal resources of the world are in the base metal sulfide deposits that are mined primarily for copper, zinc, nickel, and silver, and to a lesser extent, lead and mercury, where selenium recovery is secondary. 

Resources. World resources of silver are estimated to be about half a million tons. However, only about 250,000 metric tons are considered economically recoverable reserves. These are associated with ores of copper, gold, lead, and 2inc, and extraction depends on the economic recovery of those metals. Canada and the CIS vie for the greatest reserves of silver in the ground. 

Total reserves of thorium at commercial price in 1995 was estimated to be >2 x 10 metric tons of Th02 (H)- Thorium is a potential fuel for nuclear power reactors. It has a 3—4 times higher natural abundance than U and the separation of the product from Th is both technically easier and less expensive than the enrichment of in However, side-reaction products, such as and the intense a- and y-active decay products lead to a high... 

Air emissions for processes with few controls may be of the order of 30 kilograms lead or zinc per metric ton (kg/t) of lead or zinc produced. The presence of metals in vapor form is dependent on temperature. Leaching processes will generate acid vapors, while refining processes result in products of incomplete combustion (PICs). Emissions of arsine, chlorine, and hydrogen chloride vapors and acid mists are associated with electrorefining. 

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