Meningiomas

Reports of ChE abnormalities in tumours, e.g., meningioma, glioma, acoustic neurinomas and lung cancers, megakaryocytopoietic disorders and leukemias, ovarian tumours and neuroblastomas, suggest cell proliferation and differentiation activities. 

Cancer Elevated levels of AEA in glioblastomas, increased levels of 2-AG in meningiomas, elevated levels of both AEA and 2-AG in colorectal carcinoma, with possible anti-tumour action Inhibitors of degradation (both FAAH and cellular re-uptake)... 

NF-2 Codes for a protein that inhibits the Meningioma, ependymoma, and schwannoma... 

CCK receptors SCLC, pancreatic cancers, neuroblastomas, meningiomas, medullary thyroid carcinomas... 

Kyle RH, Oler A, Lasser EC, Rosomoff HL. 1963. Meningioma induced by thorium dioxide. New Eng J Med 368 80-82. 

Sussman S, Terbrugge KG, Solt LC, et al. 1980. Thorotrast induced meningioma case report. J Neurosurg 52 834-837. 

Kalapurakal JA, Silverman CL, Akhtar N, Laske DW, Braitman LE, Boyko OB, Thomas PR. Intracranial meningiomas factors that influence the development of cerebral edema after stereotactic radiosurgery and radiation therapy. Radiology 1997 204(2) 461-5. 

Schulze A, Bingas B. 1968. [Meningioma development induced by a foreign body], Beitr Neurochir 15 297-301. (German). 

Hancq S, Salmon I, Brotchi J, De Witte O, Gabius HJ, Heizmann CW, Kiss R, Decaestecker C. 2004a. S100A5 a marker of recurrence in WHO grade I meningiomas. Neuropathol Appl Neurobiol 30(2) 178-187. 

Child Brain tumours and meningiomas after therapeutic high-dose ionizing radiation to the head (Ron et al., 1988b Klein-schmidt Lillehei, 1995) Lead poisoning causes abnormal bone structure and poor growth (Osterloh, 1991)... 

Harrison MJ, Wolfe DE, Lau TS, Mitnick RJ, Sachdev DP (1991) Radiation-induced meningiomas Experience at the Mount Sinai Hospital and review of the literature. J Neurosurg, 75 564-574. 

Kleinschmidt D Lillehei KO (1995) Radiation-induced meningioma with a 63 year latency period. Case report. J Neurosurg, 82 487-488. 

Henze M, Dimitrakopoulou-Strauss A, Milker-Zabel S, et al. (2005) Characterization of 68Ga-DOTA-D-PHEl-TYR3-Octreotide kinetics inpatients with meningiomas. J Nucl Med 46,763-769. 

Patients with preexisting tumors or growth hormone deficiency secondary to an intracranial lesion should be examined routinely for progression or recurrence of the underlying disease process. In pediatric patients, clinical literature has revealed no relationship between somatropin replacement therapy and central nervous system (CNS) turmor recurrence or new extrracranial tumors. However, in childhood cancer survivors, an increased risk of a second neoplasm has been reported in patients treated with somatropin after their first neoplasm. Intracranial tumors, in particular meningiomas, in patients treated with radiation to the head for their first neoplasm, were the most common of these second neoplasms. In adults, it is unknown whether there is any relationship between somatropin replacement therapy and CNS tumor recurrence... 

PTCH Gorlin syndrome Transmembrane receptor Basal cell carcinoma, ovary, heart, medulloblastoma, meningioma... 

Intracranial tumor, e.g. glioma, meningioma Subdural hematoma Epileptic seizure... 

Of 326 patients with a clinical diagnosis of definite TIA, only one patient (0.3% confidence interval [Cl], 95% 0.1-1.7) was subsequently found to have symptomatic non-vascular pathology, a small subdural hematoma. Of 79 patients with a clinical diagnosis of possible TIA, two patients (2.5% 95% Cl, 0.7-8.8) were subsequently diagnosed with symptomatic non-vascular pathology, a meningioma in both cases. 

Acoustic neurofibroma Acute myeloid leukemia (AML) Astrocytoma, high grade Bladder carcinoma Breast carcinoma Colon carcinoma Lung carcinoma, small cell Lung carcinoma, other Melanoma (standard and uveal) Meningioma... 

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