Medical catheter

Figure 4 Electron micrographs of unchlorinated poly(vinyl acetate-co-oxazolidinone) (top) and chlorinated poly(vinyl acetate-co-oxazolidinone) (bottom) coated medical catheters exposed for 72 h to a flowing aqueous suspension of Pseudomonas aeruginosa (10 CFU/mL). 

Self-sterilizing Hospital Tiles to cover the floor and walls of operating rooms, silicone rubber for medical catheters and hospital garments and uniforms... 

The most experimented antimicrobial dmgs for intravascular devices are chlorhex-idine/silver sulfadiazine (CH/SS) and minocycline-rifampin (MR). From a historical point of view, CVCs coated with one of these two drugs are the first medicated catheters approved for clinical trials. 

Medical, catheter, catheter hubs, I.V. connectors, surgical instruments USP class VI, low heat resistance, excellent room temperature impact, good low temperature impact... 

Series Medical, catheters, tubing, cuffs, transdermal patches Polyether-based excellent hydrolytic stability excellent resistance to fungi and microorganisms... 

Medical catheters, connectors, tubing, syringe seals. 

Medical - catheter tubing, connectors, tubing, transdermai drug delivery patches. ... 

Biomedical Applications. In the area of biomedical polymers and materials, two types of appHcations have been envisioned and explored. The first is the use of polyphosphazenes as bioinert materials for implantation in the body either as housing for medical devices or as stmctural materials for heart valves, artificial blood vessels, and catheters. A number of fluoroalkoxy-, aryloxy-, and arylamino-substituted polyphosphazenes have been tested by actual implantation ia rats and found to generate Httle tissue response (18). 

Aliphatic isocyanates have a small but growing market application in thermoplastic polyurethanes (TPU). Medical appflcafions include wound dressings, catheters, implant devices, and blood bags. A security glass system using light-stable TPU as an inner layer is under evaluation for shatterproof automotive windshield appflcafions. 

Elastomers based on PTMEG have excellent microbial and fungus resistance. Their hydrolytic stabiUty make these elastomers prime candidates for use ia ground-contact appHcations, for example, as jacketing material for buried cables. Because of their good biocompatibiHty, they have also found uses ia medical appHcations, such as catheter tubiag. 

If it is not dissolved or trapped, an embolism moving from the lower extremities can be life-threatening. People afflicted with phlebitis are particularly susceptible to this problem. A shape-memory trap has been devised that, when deployed in the vena cava, is like a multileaved mesh that traps a traveling embolism, retaining it until medication can dissolve it. Introduced in a folded form by a catheter, the mesh is prevented from deploying by subjecting it to a flow of cold saline water. Once in place, it is released from the catheter and, warmed by body heat, opens into its final shape (11). 

Poly(tetramethylene oxide) polyols (PTMEG) are high performance polyethers that are crystalline waxes at molecular weights above 650 and liquids at lower molecular weights. They are only available as diols, but they produce adhesives with good hydrolysis resistance and moisture resistance, which is why these adhesives are even used in medical devices, blood bags, catheters, and heart-assist devices [25]. Certain thermoplastic polyurethane adhesives and solvent-borne adhesives are also based on PTMEG s. 

Hron P. Hydrophilisation of silicone rubber for medical applications. Polym Int, 2003, 52, 1531-1539. Tcholakian RK and Raad. Durability of anti-infective effect of long term silicone sheath catheters impregnated with antimicrobial agents. Antimicrob Agents Chemother, 2001, 45(7), 1990-1993. 

A detailed clinical history, past medical and surgical history, medications, allergies, laboratory work-up, physical examination, and NIHSS should be obtained as quickly as possible for assessment of inclusion and exclusion criteria for lAT. Table 4.1 lists the criteria for catheter-based reperfusion therapy currently in place at the Massachusetts General Hospital (Table 4.1 see also www.acutestroke.com for updated criteria). 

The Concentric Retriever (Concentric Medical Inc., Mountain View, CA), a flexible, nitinol wire with helical tapering coil loops (X5 and X6) that is used in conjunction with a balloon guide catheter (8 or 9 French) and a microcatheter, is the only device currently approved by the FDA for the endovascular treatment of stroke patients (Fig. 4.3). The second-generation devices (L5 and L6) differ from the X devices by the inclusion of a system of arcading filaments attached to a nontapering... 

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