Cancer cells MCF

Lee ATC, Azimahtol HLP, Tan AN. Styrylpyrone derivatives (SPD) induces apopotosis in caspases-7-dependent manner in the human breast cancer cell line MCF-7. Cancer Cell Int 2003 3 1-8. 

Cui, Y., Lu, Z., Bai, L., Shi, Z., Zhao, W.E., and Zhao, B. 2007. Beta-carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor gamma expression and reactive oxygen species production in MCF-7 cancer cells. EurJ Cancer 43 2590-2601. 

The DKPs cyclo(His-Ala) and cyclo(His-Gly) proved to have promising anticancer activity comparable with that observed for cisplatin. Cyclo(His-Ala) in particular demonstrated an ability to inhibit tumor growth in HT-29, HeLa, and MCF-7 cancer cell lines. Cyclo(His-Gly) however, only had a marked effect on MCF-7 carcinoma cells at a concentration of 100 pmol 1. Both DKPs at a concentration of 0.5 mmolwere effective against two of the three Gram-positive bacteria, that is, Bacillus and S. aureus. Cycfo(His-Gfy) was more effective against Klebsiella pneumoniae than cyclo(His-Ala). Cyclo(His-Afa) and cycfo(His-Gfy) inhibited the growth of C. albicans by 66.3 and 47%, respectively. 

Cyclo(Met-Tyr) and cyclo(Met-Trp) produced a marked inhibitory effect toward platelet adhesion induced by both ADP and thrombin. A moderate cytotoxic effect was displayed by cyclo(Met-Trp) against HeLa (55.85% inhibition), HT-29 (39.80% inhibition), and MCF-7 cancer cells (54.96% inhibition) whereas... 

In 2004, Liu et al. made an effort to incorporate estradiol into C-2, 7, and 10 positions in Taxol to target the drug to estrogen receptor (ER) positive breast cancer. For C-2 and C-7 conjugates, no satisfactory results were obtained for either activity or selectivity. But a 7-epi-lO-conjugated taxoid (119) did exhibit some selectivity between ER-positive and negative cancer cells, and ER-(3 (MDA-MB-231 cell) and ER-a expressing (MCF-7) cancer cells. " ... 

Wilk KA, Zielinska K, Pietkiewicz 1, Skolucka N, Choromahska A, Rossowska 1, Garhiec A, and Saczko J. (2012). Photo-oxidative action in MCF-7 cancer cells induced hy hydrophobic cyanines loaded in biodegradahlemicroemulsion-templated nanocapsules. International Journal of Oncology, 41, 105-116. 

O Shea, M., Devery, R., Lawless, F., Murphy, J., and Stanton, C. (2000) Milk Fat Conjugated Linoleic Acid (CLA) Inhibits Growth of Human Mammary MCF-7 Cancer Cells, Anticancer Res. 20, 3591-3601. 

Zu Y, Yu H, Liang L et al (2010) Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells. Molecules 15 3200-3210... 

Simultaneous measurement of and NOT released from MCF-7 cancer cells... 

Posey and Bierer, 1999 Okada, Sanders, and Crews, 2000). Most jaspamides/jasplakinolides have potent q to-toxic activities against HT-29, HCT-116, and MCF-7 cancer cell lines with IC50 values less than 1 pM, but jaspamides F, H, N, and P have only moderate activities with IC50 values greater than 10 pM (Ebada et al, 2009 Gala et al, 2009 Robinson et al, 2010). 

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