Manufacturing rule checks

Rules for the welded fabrication of pressure vessels cover welding processes, manufacturer s record keeping on welding procedures, welder qualification, cleaning, fit-up alignment tolerances, and repair of weld defects. Procedures for postweld heat treatment are detailed. Checking the procedures and welders and radiographic and ultrasonic examination of welded joints are covered. 

Indicate whether the chemical is manufactured (including imported), processed, or othen/vise used at the facility and the general nature of such activities and uses at the facility during the calendar year. Report activities that take place only at your facility, not activities that take place at other facilities involving your products. You must check all the blocks in this section that apply, tf you are a manufacturer of the chemical, you must check a and/or b, and at least one of c,.ji. e> orf. Refer to the definitions of manufacture," "process," and othenwise use" in the general information section of these instrilctions or section 372.3 of the rule for additional explanations. 

This rule varies from state to state. Some materials are exempt from Nuclear Regulatory Commission or State licensing requirements. Most institutions already have an institutional license which would specify the safety officer. It would be well for the clinical chemistry laboratory to check with this individual before beginning to use radioactive materials. If there is no license, many manufacturers of isotope materials will assist the laboratory in obtaining the proper license. 

Components manufactured in accordance with standards listed in Table IP-8.1 shall be considered suitable for use at pressure-temperature ratings in accordance with para. IP-2.2.2 or para IP-2.2.3, as applicable. The rules in para. IP-3.2 are intended for pressure design of components not covered in Table IP-8.1, but may be used for a special or more rigorous design of such components, or to satisfy requirements of para. IP-2.2.3. Designs shall be checked for adequacy of mechanical strength under applicable loadings enumerated in para. IP-2.1. 

Some companies may think that they can get away with anything since they don t need the FDA s stamp of approval to sell their product. They re wrong. The Dietary Supplement Health and Education Act (DSHEA) of 1994 made it clear how the FDA is to control the supplement industry and check up on manufacturers responsibilities. The manufacturer is responsible for checking that the product is safe, even though it doesn t need FDA approval to be sold. Companies must also show scientific evidence to back up any claims they make. Any company that violates the rules is informed of its violation(s) and ordered to make changes. Companies that still fail to follow the rules face serious penalties that include having the products taken away, and possible criminal charges. 

Organic solvents for HPLC are generally very good. There are three rules of thumb to remember always use HPLC grade solvents, buy from a reliable supplier, and filter your solvents and check them periodically with your HPLC. Most manufacturers do both GLC and HPLC quality control on their solvents some do a better job than others. The best way to find good solvents is to talk to other chromatographers. 

One underlying principle to be followed in purchasing a NIR instrument that should be adhered to is simply this first determine your application, then purchase an appropriate instrument [1]. All too often an analyst is enamored by a particular piece of equipment and purchases it, and, then looks for an application. This is a proven formula for failure. As a rule of thumb, the particular application should be clearly defined and specific objectives identified. Its vital steps must be identified and the location of the test determined (in-line, at-line, or in the laboratory). At that time, instrument manufacturers should be contacted, feasibility studies conducted, references checked, and reliability of any instrument determined. Then and only then should an instrument be purchased. Most instruments available today will be suitable for a variety of applications, but choosing an inappropriate instrument for a particular application surely dooms the analyst to failure. Analysts will often erroneously assume that NIR is at fault in such situations, rather than consider that they have selected an improper instrument. 

The best thing you can do is research which businesses in your area use food chemists. A rule of thumb is that if a company is connected to the manufacture or distribution of food, there will be a food chemist somewhere in the background. You might also check out the state of Idaho. It is a fabulously beautiful state and, obviously, they have jobs for food chemists. 

These rule-of-thumb methods can be used to check the declared performance and ratings from a machine manufacturer. 

The official naming convention under REACH is that developed and maintained by lUPAC. The lUPAC system is intended to allow an experienced chemist to name a structure under the system by following a set of rules. In practice, many chemical substances are very complex and application of the rules requires the interpretation of a chemist who is an expert not just in chemistry, but also in lUPAC nomenclature. Some chemicals, for the purpose of the European Inventory of Existing Chemical Substances (EINECS) and REACH, have lUPAC names that are common names rather than names that follow a set of rules. lUPAC publishes new lists of names periodically, and occasionally a common name is replaced by a more formal one. This practice results in multiple names for the same substance, and the most current name is not necessarily the one originally placed onto EINECS. CAS offers a service by which it assigns a CAS name and CASRN for a substance for which one already knows the structure and/or the reactants used in the manufacture of the substance, but there is no direct counterpart to this process to identify a correct lUPAC name. There are indirect means such as by cross-checking against a known CAS name and CASRN, or other information such as the chemical s EINECS number. 

Importers are not specifically mentioned in the statutory or regulatory statements of the PMN requirement, but in both the statute and the regulations manufacture is defined to include both manufacture and import and so all of the premanufacture notification rules that apply to manufacturers also apply to importers. Importers do not need to ensure that substances in articles are on the Inventory because articles are exempt from the PMN process. However, it is important to review the definition of article to check that all of the substances in the article meet the definition. Importers must file PMNs on all new chemicals that they import in bulk or as part of a mixture. ... 

Check of design to manufacturing design rules and capabilities. 

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