Major histocompatibility complex class genes

Kretsovali, A., Agalioti, T., Spilianakis, C., Tzortzakaki, E., Merika, M., and Papamatheakis, J. (1998) Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator. Mol. Cell. Biol. 18(11),... 

Imai Y, Ibata I, Ito D, Ohsawa K, Kohsaka S (1996) A novel gene ibal in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. Biochem Biophys Res Commun 224 855-862 Imitola J, Raddassi K, Park KI, Mueller FJ, Nieto M, Teng YD, Frenkel D, Li J, Sidman RL, Walsh CA, Snyder EY, Khoury SJ (2004) Directed migration of neural stem cells to sites of CN S injury by the stromal cell-derived factor lalpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci USA 101 18117-18122... 

Di Lorenzo, T. P., Graser, R. T., Ono, T., Christianson, G. J., Chapman, H. D., Roopenian, D. C., Nathenson, S. G. and Serreze, D. V. (1998). Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement. Proc. Natl. Acad. Sci. USA 95, 12538-12543. 

Bahram, S., Bresnahan, M., Geraghty, D. E., and Spies, T. A. (1994). A second lineage of mammalian major histocompatibility complex class I genes. Proc. Natl. Acad. Sci. USA 91, 6259-6263. 

Massa PT (1993) Specific suppression of major histocompatibility complex class I and class II genes in astrocytes by brain-enriched gangliosides. J Exp Med 178 1357-1363. 

Mehindate K, Thibodeau I, Dohlsten M, Kalland T, Sekaly RP, Mourad W Cross-linking of major histocompatibility complex class II molecules by staphylococcal enterotoxin A superantigen is a requirement for inflammatory cytokine gene expression. J Exp Med 1995 182 1573-1577. 

Shirayoshi Y, Burke PA, Appella E, Ozato K (1988) Interferon induced transcription of a major histocompatibility class I gene accompanies binding of inducible nuclear factors to the interferon consensus sequence. Proc Natl Acad Sci USA 85 5884 5888 Silacci P, Mottet A, Steimle V, Reith W, Mach B (1994) Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA. J Exp Med 180 1329- 1336... 

Imai Y, Ibata 1, Ito D et al (1996) A novel gene ibal in the major histocompatibility complex class 111 region encoding an EE hand protein expressed in a monocytic lineage. Biochem Biophys Res Commirn 224 855-862... 

Group of transmembrane proteins engaged in the presentation of small peptide fragments to T-cells. Two classes of Major histocompatibility complex (MHC) molecules exist both of which are encoded by a highly polymorphic gene cluster. MHC class I and class II proteins present peptide fragments to CD8+ and CD4+ T-cells, respectively. The human MHC is also known as HLA, the murine MHC as H-2 complex. 

The major histocompatibility complex (MHC) is, in fact, a set of genes which code for three classes of proteins -class I, class II and class III. The class I proteins are involved in identifying cells that are infected with a virus. Class II proteins are involved in the interactions between Th cells and antigens. Class III proteins are the complement proteins. Although the name major histocompatibility complex actually refers to the genes,... 

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