Macrophage phagocytosis

Kanke, M., Geissler, R. G., Powell, D., Kaplan, A., and De-Luca, P. P., Interaction of microspheres with blood constituents. III. Macrophage phagocytosis of various types of polymeric drug carriers, J. Parent. Sci. Technol., 42, 157, 1988. 

The same products were formed in the reaction of LDL with molecular chlorine but not with HOC1. These authors suggested that the formation of molecular chlorine might occur in vivo because a pH value could be less than 4 during macrophage phagocytosis. In addition, atherosclerotic tissue may also be relatively acidic due to impaired oxygen diffusion and hypoxia. 

Szabo, I.et al., Suppression of peritoneal macrophage phagocytosis of Candida albicans by opioids, J. Pharmacol. Exp. Ther., 267, 703, 1993. 

Schagat, T.L., Wofford, J.A., and Wright, J.R., Surfactant protein A enhances alveolar macrophage phagocytosis of apoptotic neutrophils, J. Immunol. 166, 4, 2727, 2001. 

Renwick, L. C., Donaldson, K., and Clouter, A. Impairment of alveolar macrophage phagocytosis by ultrafine particles. Toxicol. Appl. Pharmacol. 172 119-127, 2001. 

Nonspecific immunity Macrophage phagocytosis, bactericidal/tumoricidal activity)... 

Bacteria bind to complement components and the bacterium-complement complexes bind complement receptors on the surface of macrophages. Phagocytosis may also be mediated by specific antibodies that function as opsonins, which bind to particles, rendering them susceptible to phagocytosis. The bacterium-antibody complex then binds the macrophages via the Fc receptor and phagocytosis begins. 

Flaroz RK, Mattenberger-Kreber L. 1977. Effect of cigaret smoke on macrophage phagocytosis. ERDA Symp Ser 43 36-57. 

Macrophage Phagocytosis (engulfment and digestion) of cellular debris and pathogens, and stimulation of lymphocytes and other immune cells that respond to the pathogen Days (if activated) to years (as immature)... 

Th2 cytokines produced antibody production, macrophage phagocytosis... 

This article describes macrophage phagocytosis of polymer microspheres for the purpose of a deeper understanding of the polymer interaction with phagocytic cells. The provided information should contribute to the development of polymeric biomaterials, especially of polymer carriers applicable for drug delivery systems. 

Over the ensuing decades there have been a number of sporadic reports, in both health and disease, of macrophage phagocytosis of neutrophils, and of particular relevance to the resolution of inflammation is the clinical... 

Kar, S., Ren, Y., Savill, J.S. and Haslett, C. (1995). Inhibition of macrophage phagocytosis in vitro of aged neutrophils increases release of neutrophil contents [Abstract]. Clin. Sci., in press. 

Savill, J.S., Wyllie, A.H., Henson, J.E., Henson, P.M. and Haslett, C. (1989a). Macrophage phagocytosis of aging neutrophils in inflammation - programmed cell death leads to its recognition by macrophages. J. Clin. Invest. 83, 865-875. 

Immunostimulant effects of garlic include an increase in proliferation of lymphocyte and macrophage phagocytosis, induction of the infiltration of lymphocytes and macrophages in transplanted tumors, induction of splenic hypertrophy, increased release of interleukin (IL)-2, interferon-y, and tumor necrosis factor-a, and enhancement of natural killer cell activity. It is thought that these effects may be mechanisms of cancer prevention (49). Lau and colleagues tested an aqueous garlic extract from Japan, the protein fraction isolated from this same extract, and three additional extracts obtained from health food stores in Loma Linda, CA, for ability to stimulate murine T-lym-... 

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