Phagocytosis by macrophages

Araki N, Johnson MT, Swanson JA. A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages. J Cell Biol 1996 135(5) 1249-1260. 

When the blood concentration of glutamine decreases below that which is physiological, functional impairment can result poor proliferation of immune cells and poor phagocytosis by macrophages. 

Helper T-ceU 1 ThI CD4-H Coordination of immune response, particularly activation of phagocytosis by macrophages. 

Figure 17.23 Killing by antibodies and complement working together. Antibodies form a complex with bacteria. The anti-body-bacterium complex can stimulate phagocytosis by macrophages, directly. The complex also activates complement, which stimulates phagocytosis or causes lysis and hence death of bacteria. Activated complex can also lead to inflammation which attracts other immune cells to the site of infection (see Figure 17.24).

Tabata, Y. and Ikada, Y. (1988). Effect of the size and surface-charge of polymer microspheres on their phagocytosis by macrophage. Biomaterials, 9, 356-362. 

Javierre MQ, Pinto LV, Lima AO, Sassine WA (1975) Immunologic phagocytosis by macrophages effect by stimulation of alpha adrenergic receptors. Rev. Bras. Pesqui. Med Biol. 8 271-274. 

TaUe 3. Influence of Macromolecule Precoating of PLLA Microspheres on Phagocytosis by Macrophages... 

Stern, M., Meagher, L., Savill, J. and Haslett, C. (1992). Apoptosis in human eosinophils. Programmed cell death in the eosinophil leads to phagocytosis by macrophages and is modulated by IL-5. J. Immunol. 148, 3543-3549. 

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