Macrophage inflammatory proteins MIPs

Wetzel MA, Steele AD, Eisenstein TK, Adler MW, Henderson EE, Rogers TJ (2000) Mu-opioid induction of monocyte chemoattractant protein-1, RANTES, and IFN-gamma-inducible protein-10 expression in human peripheral blood mononuclear cells. J Immunol 165 6519-6524 Widmer U, Manogue KR, Cerami A, Sherry B (1993) Genomic cloning and promoter analysis of macrophage inflammatory protein (MIP)-2, MIP-1 alpha, and MIP-1 beta, members of the chemokine superfamily of proinflammatory cytokines. J Immunol 150 4996-5012 Ye RD (2001) Regulation of nuclear factor kappaB activation by G-protein-coupled receptors. [Review] [136 refs]. J Leukoc Biol 70 839-848... 

Robinson E, Keystone EC, Schall TJ, Gillett N, Fish EN. Chemokine expression in rheumatoid arthritis (RA) evidence of RANTES and macrophage inflammatory protein (MIP)-l beta production by synovial T cells. Clin Exp Immunol 1995 101(3) 398-107. 

Szabo C, Scott GS, Virag L, Egnaczyk G, Salzman AL, Shanley TP, Hasko G (1998) Suppression of macrophage inflammatory protein (MIP)-lalpha production and collagen-induced arthritis by adenosine receptor agonists. Br J Pharmacol 125(2) 379-387... 

Iwasaki A, Kelsall B Location of distinct Peyer s patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3a, MIP-3 3, and secondary lymphoid organ chemokines. J Exp Med 2000 191 1381-1393. 

Binding of infectious pathogens to pattern-recognition receptors stimulates the release of macrophage inflammatory protein (MIP) la, MIP-l/S, MIP-3a, and IP-10 from macrophages and dendritic cells... 

Nakayama T, Fujisawa R, Yamada H, Horikawa T, Kawasaki H, Hieshima K, Izawa D, Fujiie S, Tezuka T, Yoshie O Inducible expression of a CC chemokine liver- and activation-regulated chemokine (LARC)/macrophage inflammatory protein (MIP)-3 alpha/CCL20 by epidermal ker-atinocytes and its role in atopic dermatitis. Int Immunol 2001 13 95-103. 

Hashimoto, T., M. Abe, T. Oshima, H. Shibata, S. Ozaki, D. Inoue, and T. Matsumoto. 2004. Ability of myeloma cells to secrete macrophage inflammatory protein (MIP)-1 alpha and MIP-lbeta correlates with lytic bone lesions in patients with multiple myeloma. Br J Haematol 125 38. 

Widmer U, Manogue KR, Cerami A, Sherry B. Genomic cloning and promoter analysis of macrophage inflammatory protein (Mip) -2, Mip-la, and Mip-ip, members of the chemokine superfamUy of proinflammatory cytokines. J Immunol 1993 150 4996-5012. 

Czaplewski, L. G., McKeating, J., Craven, C. J., Higgins, L. D., Appay, V., Brown, A., et al. (1999). Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-l alpha, MIP-lbeta, and RANTES. Characterization of active disaggregated chemokine variants. The Journal of Biological Chemistry, 274(23), 16077—16084. 

Davatelis, G., Tekamp-Olson, P., Wolpe, S. D., Hermsen, K., Ouedke, C., Gallegos, C., Colt, D., Merryweather, J., and Cerami, A. (1988) Cloning and characterisation ofacDNAfor murine macrophage inflammatory protein (MIP), a novel monokine with inflammatory and chemoki-netic properties. J. Exp. Med. 167, 1939-1944. 

Marshall, E., Woolford, L. B., and Lord, B. I. (1997) Continuous infusion of macrophage inflammatory protein MIP-la enhances leucocyte recovery and haematopoietic progenitor cell mobilisation after cyclophosphamide. Br. J. Cancer 75,1715-1720. 

Dolei, A., Biolchini, A., Serra, C., Curreli, S., Gomes, E., and Dianzani, F. (1998). Increased replication of T-cell-tropic HIV strains and CXC-chemokine receptor-4 induction in T cells treated with macrophage inflammatory protein (MIP)-lalpha, MIP-lbeta and RANTES beta-chemokines. AIDS 12, 183 190. 

Macrophage inflammatory protein (MIP) la mRNA was upregulated in human peripheral blood monocytes after a 4-6 h exposure to 100 ig Min-U-Sil/ml (Erkan et al. 1997). 

Methicillin-resistant Staphylococcus aureus (MRSA) is an important infection in bum-injured patients. Improvement of the immune system by IL-18 treatment increased the survival of bum-injured mice submitted to MRS A infection. IL-18 increased the serum levels of TNF, IL-17, IL-23, granulocyte colony-stimulating factor (G-CSF), macrophage inflammatory protein (MIP-2), and neutrophil counts. The treatment also improved... 

The role of GSH in detoxification of HD has been somewhat controversial. Sciuto et al. (2007) have shown that there may be a biphasic response to HD intoxication. Testing for pulmonary toxicity using an intravascular HD injection model in rats, it was shown that at Ih post-exposure, BAL revealed a dose-dependent inflammatory stage that decreased over time from 3 to 24 h. Macrophage inflammatory protein (MIP-2) was the predominant chemokine in the BAL followed by ILlp, ILIO, and TNFa. A second phase involved changes in the antioxidant response pathway, which was mostly affected at 6h post-challenge. HD exposure increased BALF protein, GSH, and the activities of GSH peroxidase (GPX), catalase, GSH reductase, and SOD (Sciuto et al., 2007). Laskin et al. (2010) summarized that in some animal models of acute lung injury with HD and HD-like compounds, antioxidant markers such as GPX and GSH... 

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