Macaca

Finocchio DV, Luschei ES, Mottet NK, Body RL. 1980. Effects of methylmercury on the visual system of the rhesus macaque (Macaca mulatto). I. Pharmacokinetics of chronic methylmercury related to changes in vision and behavior. In Merigan WH, Weiss B, editors. Neurotoxicity of the visual system. New York Raven Press, p. 113-122. 

Azmitia, E.C., and Gannon, P.J. The primate serotonergic system A review of human and animal studies and a report on Macaca fascicularis. 

Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-indueed parkinsonian syndrome in Macaca fascicularis Which midbrain dopaminergic neurons are lost Neuroscience 24 161-174, 1988. 

Kosofsky, B.E. Molliver, M.E. Morrison, J.H. and Foote, S.L. The serotonin and norepinephrine innervation of primary visual cortex in the Cynomolgus monkey (Macaca fascicularis). J Comp Neurol 230 168-178, 1984. 

Zingeser M.R. (1984). The nasopalatine ducts and associated structures in the rb monkey (Macaca mulatto) — topography, prenatal development, function phylogeny. Am J Anat 170, 581-595. 

Domino, E.F. Fukuda, N. and Simonic, A. Comparative electro-encephalographic and gross behavioral effects of phencyclidine, related substances and various centrally acting drugs in Macaca mul atta. In Kamenka, J.M. Domino, E.F. and Geneste, P., eds. Phencvli di ne and Rel ated Arvl cvclohexvlami nes Present and Future Appl i cat.i ons. Ann Arbor, MI NPP Books, 1983a. pp. 369-395. 

Monkey (Macaca (ascicuiaris) 19-14 yr (C) Hemato 2 Rice 1996 PbAc... 

Foster WG, Singh A, McMahon A, et al. 1998. Chronic lead exposure effects in the cynomolgus monkey (macaca fascicularis) testis. Ultrastruct Pathol 22(1) 63-71. 

Hopper DL, Keman WJ, Lloyd WE. 1986. The behavioral effects of prenatal and early postnatal lead exposure in the primate Macaca fascicularis. Toxicol Ind Health 21 1-16. 

Munro IC, Willes RF, True love JF. 1975. Absorption and tissue distribution of inorganic lead in the developing infant monkey (Macaca irus). Toxicol Appl Pharmacol 32 128-129. 

Pounds JG, Marlar RJ, Allen JR. 1978. Metabolism of lead-210 in juvenile and adult Rhesus monkeys Macaca mulatta. Bull Environ Contain Toxicol 19 684-691. 

Rice DC, Willes RF. 1979. Neonatal low-level lead exposure in monkeys (Macaca fascicuiaris) Effect on two choice non-spatial form discrimination. J Environ Pathol Toxicol 2 1195-1203. 

Daley J., Turner R., Becker D., Bliwise D., Rye D. (1998). Telemetric recording of sleep in macaca mulatta prior to systemic MPTP. Sleep 21(Suppl.)(3), 6. 

Higley, J. D., Thompson, W. W., Champoux, M. et al. Paternal and maternal genetic and environmental contributions to cerebrospinal fluid monoamine metabolites in Rhesus monkeys (Macaca mulatto). Arch. Gen. Psych. 50 615-623,1993. 

Intramuscular injection of 5 mg Pb+2/kg BW daily during pregnancy or lactation Cynomolgus monkey, Macaca fascicularis Abortions and death in pregnant monkeys cerebral pathology in newborns 19... 

As above, except dose is 50 pg Pb/kg BW Rhesus monkey, Macaca mulatta Blood lead 154 pg/L (vs. 35 pg/L in controls), declining to 109 pg/L at day 150 postadministration. At age 3 years, group showed impaired color discrimination. No overt signs of toxicity, normal blood chemistry (except lead), normal growth and development skills 21... 

Rhesus monkey, Macaca mulatta 0.5 mg/kg BW during days 20-30 of pregnancy Maternally toxic, and abortient 1... 

Monkeys, Macaca fascicularis adults age 7-10 years Monkeys, Macaca fascicularis female adults Monkeys, Macaca spp. Exposed in utero maternal doses of 0, 50, 70, or 90 pg methylmercury/ kg BW daily resulted in blood mercury levels in treated infants of 1.0-2.5 mg/L offspring were conditioned and tested for ability to respond to a lit button for an apple juice reward and other tasks Daily dose of methylmercury chloride in apple juice for 150 days equivalent to daily doses of 0.0, 0.4, 4.0, or 50.0 pg methylmercury/kg BW Various... 

Petruccioli, L. and P. Turillazzi. 1991. Effect of methylmercury on acetylcholinesterase and serum cholinesterase activity in monkeys, Macaca fascicularis. Bull. Environ. Contam. Toxicol. 46 769-773. 

Cynomolgus monkey, Macaca 0.75 mg/kg BW Single intravenous (iv) injection produced reduced appetite 7 days postexposure 13... 

Reuhl, K.R., S.G. Gilbert, B.A. Mackenzie, J.E. Mallett, and D.C. Rice. 1985. Acute trimethyltin intoxication in the monkey (Macaca fascicularis). Toxicol. Appl. Pharmacol. 79 436-152. 

Murray, S., L.A. Tell, and M. Bush. 1997. Zinc toxicosis in a Celebes ape (Macaca nigra) following ingestion of pennies. Jour. Zoo Wildl. Med. 28 101-104. 

MONKEY, Macaca fascicularis 1 or 10 mg/kg BW of trans-chlordane given once weekly for 5 weeks by subcutaneous injection. Adipose tissue, blood, and skin lipids analyzed for up to 20 weeks after the last injection trans-Chlordane and oxychlordane were detected in all tissues. In blood and adipose tissue, trans-chlordane decreased rapidly and oxychlordane increased gradually until a plateau was reached. Good correlations were determined for all chemicals between blood and adipose tissue, regardless of collection time and dose level, and between skin lipids and adipose tissue. At the high dose, trans-chlordane reached a maximum of 35 mg/kg FW in adipose tissue, but was not detectable after 20 weeks. The oxychlordane concentration in adipose tissue of the high-dose group was 25 mg/kg FW after the last injection, and 18 mg/kg FW after 20 weeks (Sasaki et al. 1992)... 

Sasaki, K., Y. Kawasaki, K. Sekita, T. Ochai, M. Takeda, and M. Uchiyama. 1992. Disposition of beta-hexachlorocyclohexane, p, //-DDT, and trans-chlordane administered subcutaneously to monkeys (Macaca fascicularis). Arch. Environ. Contam. Toxicol. 22 25-29. 

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