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Macaca monkeys

There are several ways to purify a primary RPE culture.88,96-100 The process of isolation, culture technique, and cryopreservation is well documented.98,99 Grown on porous supports, RPE cells have been applied in a limited number of permeability and toxicity studies.88 The isolation and culture technique of primary RVE cells from Macaca monkeys is also documented 101 however, their application in drug permeability studies has been minimal.88... [Pg.115]

Tryphonas H, Lacroix F, FEayward S, Izaguirre C, Parenteau M, Fournier J. Cell surface marker evaluation of infant Macaca monkey leukocytes in peripheral whole blood using simultaneous dual-color immunophenotypic analysis. J Med Primatol 1996 25 89-105. [Pg.125]

In-vitro demethylation of MeMg" " has been reported to involve hydroxyl radicals, produced by cytochrome P-450 reductase (Suda and Hirayama 1992) or hypochlorous acid scavengers (Suda and Takahashi 1992). Autometallographic studies on brains of MeHg-exposed Macaca monkeys showed that the astrocytes, and possibly microglia, are the primary location of the demethyla-... [Pg.966]

Female adult Macaca monkeys (N = 22) Pb injected, i.m. 1 or 5 mg Pb/kg/day, gestation and/or lactation Abortions, maternal death, fetal effects High dose caused abortions and maternal death lower dose caused maternal kidney effects and fetal cerebral injury Tachon etal. (1983)... [Pg.555]

Kosofsky, B.E. Molliver, M.E. Morrison, J.H. and Foote, S.L. The serotonin and norepinephrine innervation of primary visual cortex in the Cynomolgus monkey (Macaca fascicularis). J Comp Neurol 230 168-178, 1984. [Pg.300]

Zingeser M.R. (1984). The nasopalatine ducts and associated structures in the rb monkey (Macaca mulatto) — topography, prenatal development, function phylogeny. Am J Anat 170, 581-595. [Pg.260]

Monkey (Macaca (ascicuiaris) 19-14 yr (C) Hemato 2 Rice 1996 PbAc... [Pg.164]

Foster WG, Singh A, McMahon A, et al. 1998. Chronic lead exposure effects in the cynomolgus monkey (macaca fascicularis) testis. Ultrastruct Pathol 22(1) 63-71. [Pg.522]

Munro IC, Willes RF, True love JF. 1975. Absorption and tissue distribution of inorganic lead in the developing infant monkey (Macaca irus). Toxicol Appl Pharmacol 32 128-129. [Pg.552]

Pounds JG, Marlar RJ, Allen JR. 1978. Metabolism of lead-210 in juvenile and adult Rhesus monkeys Macaca mulatta. Bull Environ Contain Toxicol 19 684-691. [Pg.564]

Rice DC, Willes RF. 1979. Neonatal low-level lead exposure in monkeys (Macaca fascicuiaris) Effect on two choice non-spatial form discrimination. J Environ Pathol Toxicol 2 1195-1203. [Pg.567]

Higley, J. D., Thompson, W. W., Champoux, M. et al. Paternal and maternal genetic and environmental contributions to cerebrospinal fluid monoamine metabolites in Rhesus monkeys (Macaca mulatto). Arch. Gen. Psych. 50 615-623,1993. [Pg.906]

Intramuscular injection of 5 mg Pb+2/kg BW daily during pregnancy or lactation Cynomolgus monkey, Macaca fascicularis Abortions and death in pregnant monkeys cerebral pathology in newborns 19... [Pg.312]

As above, except dose is 50 pg Pb/kg BW Rhesus monkey, Macaca mulatta Blood lead 154 pg/L (vs. 35 pg/L in controls), declining to 109 pg/L at day 150 postadministration. At age 3 years, group showed impaired color discrimination. No overt signs of toxicity, normal blood chemistry (except lead), normal growth and development skills 21... [Pg.312]

Rhesus monkey, Macaca mulatta 0.5 mg/kg BW during days 20-30 of pregnancy Maternally toxic, and abortient 1... [Pg.406]

Monkeys, Macaca fascicularis adults age 7-10 years Monkeys, Macaca fascicularis female adults Monkeys, Macaca spp. Exposed in utero maternal doses of 0, 50, 70, or 90 pg methylmercury/ kg BW daily resulted in blood mercury levels in treated infants of 1.0-2.5 mg/L offspring were conditioned and tested for ability to respond to a lit button for an apple juice reward and other tasks Daily dose of methylmercury chloride in apple juice for 150 days equivalent to daily doses of 0.0, 0.4, 4.0, or 50.0 pg methylmercury/kg BW Various... [Pg.414]

Petruccioli, L. and P. Turillazzi. 1991. Effect of methylmercury on acetylcholinesterase and serum cholinesterase activity in monkeys, Macaca fascicularis. Bull. Environ. Contam. Toxicol. 46 769-773. [Pg.437]

Cynomolgus monkey, Macaca 0.75 mg/kg BW Single intravenous (iv) injection produced reduced appetite 7 days postexposure 13... [Pg.619]

Reuhl, K.R., S.G. Gilbert, B.A. Mackenzie, J.E. Mallett, and D.C. Rice. 1985. Acute trimethyltin intoxication in the monkey (Macaca fascicularis). Toxicol. Appl. Pharmacol. 79 436-152. [Pg.631]

MONKEY, Macaca fascicularis 1 or 10 mg/kg BW of trans-chlordane given once weekly for 5 weeks by subcutaneous injection. Adipose tissue, blood, and skin lipids analyzed for up to 20 weeks after the last injection trans-Chlordane and oxychlordane were detected in all tissues. In blood and adipose tissue, trans-chlordane decreased rapidly and oxychlordane increased gradually until a plateau was reached. Good correlations were determined for all chemicals between blood and adipose tissue, regardless of collection time and dose level, and between skin lipids and adipose tissue. At the high dose, trans-chlordane reached a maximum of 35 mg/kg FW in adipose tissue, but was not detectable after 20 weeks. The oxychlordane concentration in adipose tissue of the high-dose group was 25 mg/kg FW after the last injection, and 18 mg/kg FW after 20 weeks (Sasaki et al. 1992)... [Pg.870]

Sasaki, K., Y. Kawasaki, K. Sekita, T. Ochai, M. Takeda, and M. Uchiyama. 1992. Disposition of beta-hexachlorocyclohexane, p, //-DDT, and trans-chlordane administered subcutaneously to monkeys (Macaca fascicularis). Arch. Environ. Contam. Toxicol. 22 25-29. [Pg.884]

Sv Rhesus monkey, Macaca mulatta Permanent sterility, males 13... [Pg.1719]

Dukes M, Waterton JC, Wakeling AE (1993) Antiuterotrophic effects of the pure antioestrogen ICI 182,780 in adult female monkeys (Macaca nemestrina) quantitative magnetic resonance imaging. J Endocrinol 138 203-210... [Pg.165]

Weston, R.E. and Karel, L. 1947. An adaptation of the dosimeteric method for use in smaller animals. The retained median lethal dose and the respiratory response in normal, unanesthetized, Rhesus monkeys (Macaca mulatto) exposed to phosgene. J. Ind. Hyg. Toxicol. 29 29-33. [Pg.80]

DiGiacomo, R.F. and Shah, K.V (1972). Virtual absence of infection with Herpesvirus simiae in colony-reared rhesus monkeys (Macaca mulatto) with a literature review on antibody prevalence in natural and laboratory populations. Lab. Anim. Sci. 21 61-67. [Pg.630]

Brandt I, Brittebo EB, Kowalski B, et al. 1987. Tissue binding of 1,2-dibromoethane in the cynomolgus monkey (Macaca fascicularis). Carcinogenesis 8 1359-1361. [Pg.114]

See other pages where Macaca monkeys is mentioned: [Pg.558]    [Pg.558]    [Pg.195]    [Pg.197]    [Pg.225]    [Pg.227]    [Pg.244]    [Pg.365]    [Pg.312]    [Pg.670]    [Pg.680]    [Pg.722]    [Pg.813]    [Pg.871]    [Pg.944]    [Pg.946]    [Pg.1052]    [Pg.1143]    [Pg.1180]    [Pg.1181]    [Pg.1218]    [Pg.1441]    [Pg.1525]    [Pg.141]    [Pg.248]   
See also in sourсe #XX -- [ Pg.137 ]



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