Lung diseases, environmentally

Beryllium, beryllium-containing aUoys, and beryUium oxide ceramic in soHd or massive form present no hazard whatsoever (31). SoHd shapes may be safely handled with bare hands (32) however, care must be taken in the fabrication and processing of beryUium products to avoid inhalation of airborne beryUium particulate matter such as dusts, mists, or fumes in excess of the prescribed workplace exposure limits. Inhalation of fine airborne beryUium may cause chronic beryUium disease, a serious lung disease in certain sensitive individuals. However, the vast majority of people, perhaps as many as 99%, do not react to beryUium exposure at any level (33). The biomedical and environmental aspects of beryUium have been summarized (34). 

Effects of indoor air pollutants on humans are essentially the same as those described in Chapter 7. However, there can be some additional pollutant exposures in the indoor environment that are not common in the ambient setting. From the listing in Table 23-1, radon exposures indoors present a radiation hazard for the development of lung cancer. Environmental tobacco smoke has been found to cause lung cancer and other respiratory diseases. Biological agents such as molds and other toxins may be a more likely exposure hazard indoors than outside. 

ALA fights lung disease in all its forms, with special emphasis on asthma, tobacco control, and environmental health. 

Fisher, A., M.T. Pavlova, and V.T. Covello, eds. 1991. Evaluation and Effective Risk Communications Workshop proceedings. EPA/600/9-90/054. Interagency Task Force on Environmental Cancer and Heart and Lung Disease, Center for Environmental Research Information. U.S. Environmental Protection Agency, Washington, DC. 

Brody, AR Tulane University of Louisiana, New Orleans, LA Epithelial growth factors in environmental lung disease NHLBI... 

Heintz, NH University of Vermont St Agric College, Burlington, VT Asbestos and NOj in environmental lung disease NIEHS... 

Emri S, Demit A, Dogan M, etal. (2002) Lung diseases due to environmental exposures to erionite and asbestos in turkey. Toxicology Letters 127 251-257. 

About 10% of the U.S. population (more than 30 million people) suffers from chronic lung diseases. Of these, about 12 million experience at least one asthma attack annually. The causes for this respiratory disease epidemic include environmental exposures to chemical as well as biological agents. ... 

Cigarette smoking is the primary modifiable risk factor for the development of COPD however, the disease can be attributed to a combination of risk factors that results in lung injury and tissue destruction. The risk factors associated with the development of COPD can be divided into host factors and environmental factors (Table 27-1), and commonly, the interaction between these risks leads to expression of the disease. Host factors, such as genetic predisposition, may not be modifiable but are important for identifying patients at high risk of developing the disease. Environmental factors, such as tobacco smoke and occupational dust and chemicals, are modifiable factors that, if avoided, may reduce the risk of disease development. 

Primary Smoking reduction programmes to control lung cancer, ischaemic heart disease, chronic bronchitis and other diseases Environmental control of chemicals that cause asthma... 

Attanoos RL, Gibbs AR. Pseudomesotheliomatous carcinomas of the pleura A 10-year analysis of cases from the Environmental Lung Disease Research Group. Cardiff Histopathol. 2003 43 444-452. 

Early in 1917 two young Public Health Service doctors arrived in Butte, Montana, and prepared to begin a study of the lung diseases and other ailments that afflicted the city s copper miners. Here came together for the first time a pair of men whose scientific and political influence would shape environmental policy for decades to come. 

Taatjes DJ, Palmer CJ, Pantano C, Hoffmann SB, Cummins A, Mossman BT (2001) Laser-based microscopic approaches application to cell signaling in environmental lung disease. Biotechniques 31 880-882, 884, 886-888, 890, 892-894. 

Toxicologic Data" and the "Workshop on the Effects of Pesticides on Human Health" which was organized by the Task Force on Environmental Cancer, Heart and Lung Disease) have recommended methods and test batteries that would detect sensory, motor, autonomic, cognitive and behavioral dysfunction. 

Beryllium is one of the most toxic elements in the Periodic Table. It is the agent responsible for chronic beryllium disease (CBD), an often-fatal lung disease, and is a Class A carcinogen (as determined by the U.S. Environmental Protection Agency). The primary route of human exposure to beryllium and beryllium compounds is inhalation. 

Molecular Basis for Defective Elastic Tissue in Environmentally Induced Lung Disease Pulmonary Emphysema... 

D.W. Urry, R.S. Bhatnagar, H. Sugano, K.U. Prasad, and R.S. Rapaka, A Molecular Basis for Defective Elastic Tissue in Environmentally Induced Lung Disease. In Molecular Basis of Environmental Toxicity, R.S. Bhatnagar, Ed., Ann Arbor Scientific Publishers, Inc., Ann Arbor, MI, pp. 515-530, 1980. 

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