Liquid chromatography-isotope ratio mass spectrometry

Figure 14.17 Schematic diagram of the ThermoElectron liquid chromatography isotope ratio mass spectrometry chemical oxidation reactor...

McCullagh, J. S. O., Juchelka, D. and Hedges, R. E. M. (2006) Analysis of amino acid 13C abundance from human and faunal bone collagen using liquid chromatography/isotope ratio mass spectrometry. Rapid Communications in Mass Spectrometry 20, 2761 2768. [Pg.429]

Liquid Chromatography While GC-IRMS instruments were commercialized in 1998, the interface allowing liquid chromatography-isotope ratio mass spectrometry (LC-IRMS) coupling was not commercially available until 2004 [38]. Godin et al. [39] provide a schematic overview of an LC instrument interfaced... [Pg.351]

Hettmann,A., Brand,W.A., Gleixner, G. (2007) Improved isotope ratio measurement performance in liquid chromatography/isotope ratio mass spectrometry by removing excess oxygen. Rapid Commun. Mass Spectrom., 27,4135 141. [Pg.367]

McCullagh, J.S.O., Gaye-Siessegger, J., Focken, U. (2008) Determination of underivatized amino add 5 C by liquid chromatography/isotope ratio mass spectrometry for nutritional studies the effect of dietary non-essential amino acid profile on the isotopic signature of individual amino acids in fish. Rapid Communications in Mass Spectrometry, 22,1817-1822. [Pg.792]

Smith, C.I., Fuller, B.T., Choy, K., Richards, M.P. (2009) A three-phase liquid chromatographic method for 5 C analysis of amino acids from biological protein hydrolysates using liquid chromatography-isotope ratio mass spectrometry. Analytical Biochemistry, 390,165-172. [Pg.792]

Elflein, L. and Raezke, KP. (2008) Improved detection of honey adulteration by measuring drSerences between C-13/C-12 stable carbon isotope ratios of protein and sugar compounds with a combination of elemental analyzer-isotope ratio mass spectrometry and liquid chromatography—isotope ratio mass spectrometry (delta C-13-EA/LC-IRMs). Apidologie, 39 (5), 574-587. [Pg.159]

See also Drug Metabolism Metabolite Isolation and Identification. Liquid Chromatography Isotope Separations. Mass Spectrometry Stable Isotope Ratio. [Pg.894]

GD/IRMS. glow discharge isotope ratio mass spectrometry HPLC. high-pressure liquid chromatography... [Pg.445]

Meier Augenstein, W., Watt, P. W. and Langhans, C. D. (1996) Influence of gas chromatographic parameters on the measurement of 13C/12C isotope ratios by gas liquid chromatography combustion isotope ratio mass spectrometry. I. Journal of Chromatography, A 752, 233 241. [Pg.429]

GC = gas chromatography, Py = pyrolysis (flash or hydrous heating), MS = mass spectrometry (HR = high resolution), IRMS = isotope ratio mass spectrometry, HPLC = high-pressure liquid chromatography, EC = electron capture. Cl = chemical ionization, NMR = nuclear magnetic resonance spectrometry. X-ray = X-ray crystallography. [Pg.89]

IRMS LC MDGC MS MSA NIF NMR OAV OSV PCA RAS RP SDE SFE SIM SNIF SPME TIC TLC Stable Isotope Ratio Mass Spectrometry Liquid Chromatography MultiDimensional Gas Chromatography Mass Spectrometry Multivariate Sensory Analysis Nasal Impact Frequency Nuclear Magnetic Resonance spectroscopy Odor Activity value Odor Spectrum Value Principal Component Analysis Retronasal Stimulation Reversed Phase Simultaneous steam Distillation Extraction Supercritical Fluid Extraction Selected Ion Monitoring Surface of Nasal Impact Frequency Solid Phase Micro Extraction Total Ion Current Thin Layer Chromatography... [Pg.9]

R. J. Caimi and J. T. Brenna, High-precision liquid chromatography-combustion isotope ratio mass spectrometry. Anal Chem. 65, 3497-3500 (1993)... [Pg.285]

See also Gas Chromatography Overview. Ion Exchange Ion Chromatography Applications. Isotope Ratio Measurements. Liquid Chromatography Reversed Phase. Mass Spectrometry Mass Separation Stabie isotope Ratio. [Pg.2737]

Godin, J.-E, Hopfgartner, G., Fay, L. (2008) Temperature-programmed high-performance liquid chromatography coupled to isotope ratio mass spectrometry. Anal. Chem. 80(18), 7144-7152. [Pg.367]

RJ Caimi, JT Brenna. High-sensitivity liquid chromatography-combustion isotope ratio mass spectrometry of fat-soluble vitamins. J Mass Spectrom 30 466-472, 1995. [Pg.238]

Spectroscopic techniques used in essential oil analysis comprise ultraviolet and visible spectrophotometry, infrared spectrophotometry (IR), mass spectrometry (MS), and nuclear magnetic resonance spectroscopy (NMR), including the following H-NMR, C-NMR, and site-specific natural isotope fractionation NMR. Combined techniques (hyphenated techniques) employed in essential oil analysis are GC/MS, liquid chromatography/mass spectrometry, gas chromatography/Fourier transform infrared spectrophotometry (GC/FT-IR), GC/FT-IR/MS, GC/atomic emission detector, GC/isotope ratio mass spectrometry, multidimensional GC/MS. [Pg.393]

Residues of isoxaflutole, RPA 202248 and RPA 203328 are extracted from surface water or groundwater on to an RP-102 resin solid-phase extraction (SPE) cartridge, then eluted with an acetonitrile-methanol solvent mixture. Residues are determined by liquid chromatography/tandem mass spectrometry (LC/MS/MS) on a Cg column. Quantitation of results is based on a comparison of the ratio of analyte response to isotopically labeled internal standard response versus analyte response to internal standard response for calibration standards. [Pg.510]

Krummen, M., Hilkert, A. W., Juchelka, D., Duhr, A., Schluter, H. J. and Pesch, R. (2004) A new concept for isotope ratio monitoring liquid chromatography/mass spectrometry. Rapid Communications in Mass Spectrometry 18, 2260 2266. [Pg.428]

Chemical separations may be specific for the analyte of interest (see Chapter 3), such as liquid or gas chromatography, or scavenging (such as by precipitation) to remove the major interfering substances. Addition of carrier, as practiced in radioanalytical chemistry to assist in purifying radionuclides, usually is not appropriate for mass spectrometric analysis. Such addition undermines the isotopic ratio measurements that are often at the heart of this procedure, and also overloads the system for ion generation and peak resolution (but carrier addition is used for accelerator mass spectrometry). Addition of tracers, known as isotope dilution, is often employed for yield determination (see Section 17.2.9). Interferences are distinctly different in radiometric and MS analyses of radionuclides, and may be the deciding factor in selecting one method versus the other. [Pg.364]