Linear ion trapping

Martinez Bueno MJM, Agiiera A, Gomez MJ, Hernando MD, Garcia JE, Fernandez-Alba AR (2007) Application of liquid chromatography/quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry to the determination of pharmaceuticals and related contaminants in wastewaters. Anal Chem 79 9372-9384... 

Farre M, Perez S, Gajda-Schrantz K, Osorio V, Kantiani L, Ginebreda A, Barcelo D (2010) First determination of C60 and C70 fullerenes and N-methylfulleropyrrolidine C60 on the suspended material of wastewater effluents by liquid chromatography hybrid quadrupole linear ion trap tandem mass spectrometry. J Hydrol 383(l-2) 44-51... 

Jelic A, Petrovic M, Barcelo D (2009) Multi-residue method for trace level determination of pharmaceuticals in solid samples using pressurized liquid extraction followed by liquid chromatography/quadrupole-linear ion trap mass spectrometry. Talanta 80 363-371... 

QqLIT-MS-MS Quadrupole linear ion trap tandem mass spectrometer... 

A three-dimensional ion trap is formed by three electrodes, two end caps and a ring electrode in the linear ion trap different electrodes form each of the four edges (Figure 2.11). 

Mass spectrometric analysis was performed with a hybrid triple quadrupole/ linear ion trap Applied Biosystem MSD Sciex 4000QTRAP (Applied Biosystems, Foster City, USA) instrument equipped with a Turbospray ESI interface. For target quantitative analyses, data acquisition was performed in SRM, recording the transitions between the precursor ion and the two most abundant fragment ions. The developed instrumental method display excellent LODs in SRM mode between 0.5 and 1.2 pg (Table 2). 

QqLIT Triple quadrupole-linear ion trap mass analyzer... 

Guerra P, Eljarrat E, Barcelo D (2008) Enantiomeric specific determination of hexabromo-cyclododecane by liquid chromatography-quadrupole linear ion trap mass spectrometry in sediment samples. J Chromatogr A 1203 81-87... 

FIGU RE 5.1 Ion path for 4000 QTRAP, showing linear ion trap design in Q3. (Courtesy of Applied Biosystems, Foster City, California.)... 

One of the best tools for metabolite profiling is the hybrid QTRAP MS/MS system (Applied Biosystems).119-121 While the hybrid QTRAP MS/MS was initially considered a premier tool for metabolite identification, it has more recently been seen as a tool for quantitation and metabolite profiling. Li et al.122 described the use of a hybrid QTRAP MS/MS system for discovery PK assays plus metabolite profiling in the same analytical procedure. Because QTRAP MS/MS may be used as a triple quadrupole MS system, it can be used as part of a quantitative HPLC/MS/MS system. Because QTRAP MS/MS also has linear ion trap capabilities, it can be used for metabolite screening and characterization—essentially it combines the capabilities of a triple quadrupole mass spectrometer and a linear ion trap mass spectrometer. 

M. V. Gorshkov and R. A. Zubarev. On the Accuracy of Polypeptide Masses Measured in a Linear Ion Trap. Rapid Commun. Mass Spectrom., 19(2005) 3755-3758. 

J. R. Yates, D. Cociorva, L. Liao, and V. Zabrouskov. Performance of a Linear Ion Trap-Orbitrap Hybrid for Peptide Analysis. Anal. Chem., 78(2006) 493-500. 

A. Makarov, E. Denisov, A. Kholomeev, W. Balschun, O. Lange, K. Strupat, and S. Homing. Performance Evaluation of a Hybrid Linear Ion Trap/Orbitrap Mass Spectrometer. Anal. Chem., 78(2006) 2113-2120. 

Linear combination of atomic orbitals (LCAO) method, 16 736 Linear condensation, in silanol polycondensation, 22 557-558 Linear congruential generator (LCG), 26 1002-1003 Linear copolymers, 7 610t Linear density, 19 742 of fibers, 11 166, 182 Linear dielectrics, 11 91 Linear elastic fracture mechanics (LEFM), 1 509-510 16 184 20 350 Linear ethoxylates, 23 537 Linear ethylene copolymers, 20 179-180 Linear-flow reactor (LFR) polymerization process, 23 394, 395, 396 Linear free energy relationship (LFER) methods, 16 753, 754 Linear higher a-olefins, 20 429 Linear internal olefins (LIOs), 17 724 Linear ion traps, 15 662 Linear kinetics, 9 612 Linear low density polyethylene (LLDPE), 10 596 17 724-725 20 179-211 24 267, 268. See also LLDPE entries a-olefin content in, 20 185-186 analytical and test methods for,... 

The next higher level of performance can be achieved by replacing the oaTOF MS2 with an FT-ICR analyzer while employing a linear ion trap (Thermo Electron LTQ-FT) or a quadmpole as MSI (Bruker Daltonik APEX-Q). 

Collings, B.A. Campbell, J.M. Mao, D. Douglas, D.J. A Combined Linear Ion Trap TOF System With Improved Performance and MS Capabilities. Rapid Commun. Mass Spectrom. 2001, 75, 1777-1795. 

Hager, J.W. A New Linear Ion Trap Mass Spectrometer. Rapid Commun. Mass Spectrom. 2002,16, 512-526. 

Wang, Y. Franzen, J. The Non-Linear Ion Trap. Part 3. Multipole Components in Three Types of Practical Ion Trap. Int. J. Mass Spectrom. Ion Proc. 1994, 132, 155-172. 

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