Leucocyte migration

For in vitro testing of nickel contact sensitivity, the lymphocyte transformation test and leucocyte migration inhibition test have been used [370]. 

Leukocyte migration inhibition. Ethanol (80%) extract of the dried rhizome, administered intragastrically to rats at a dose of 800 mg/kg, was active vs sheep erythrocyte-induced leucocyte migration " . 

The opioids modulate the immune system by effects on lymphocyte proliferation, antibody production, and chemotaxis. In addition, leucocytes migrate to the site of tissue injury and release opioid peptides, which in turn help counter inflammatory pain. However, natural killer cell cytolytic activity and lymphocyte proliferative responses to mitogens are usually inhibited by opioids. Although the mechanisms involved are complex, activation of central opioid receptors could... 

Glucocorticoids inhibit pathways that normally lead to production of prostaglandins, leukotrienes and platelet activating factor. These mediators would normally contribute to increased vascular permeability and subsequent changes including oedema, leucocyte migration, fibrin deposition. 

Cellular immunity The decline in T lymphocytes resulting from a drop in the number of CD8+ suppressor cells points to pre-existing cellular immunity (increase in the quotient CD4+ CDS" ), as does a rise in B lymphocytes (with an increase in T l)miphocytes in the portal fields) an inhibition of leucocyte migration was likewise found. D.H. Adams et al. (1991) identified an elevated expression of the ICAM 1 on the bile-duct epithelia. 

Saurat JH, Ponvert C, Burtin C, Soubrane C, Lebel B, Bencher F, Paupe J (1976) Lymphocyte transformation, leucocyte migration, specific IgE, IgG, and IgM before, during and after penicillin treatment without adverse reaction. Acta Allergol 31 1... 

Soborg M (1971) The leucocyte migration technique for in vitro detection of cellular hypersensitivity in man. In Bloom BR (ed) In vitro methods in cell-mediated immunity. Academic Press, New York... 

Nessi R, Domenichini E, Fowst G (1973) Allergic reactions during rifampicin treatment a review of published cases. Scand J Respir Dis [Suppl] 84 15-19 Nordquist B, Rossman H (1967) Leucocytic migration in vitro as an indicator of allergy in eczematons contact dermatitis. Trans St John s Hosp Dermatol Soc 53 154-159 Nyirenda R, Gill GV (1977) Stevens-Johnson syndrome due to rifampicin. Br Med J 2 1189 Olson CA, Riley HJ Jr (1966) Complications of tetracycline therapy. J Pediatr 68 783-791 O Mahony MG (1973) Observations on antibody reaction scores on individual patients. Scand J Respir Dis [Suppl] 84 64-72... 

PVP-I was reported to inhibit leucocyte migration and fibroblast aggregation in surgical wounds (Viljanto 1980). The use of PVP-I should therefore be avoided in the so-called red (granulomatous) phase of woundhealing. 

There was no evidence from cell-free assay systems that carvedilol is a scavenger for 02 or NO (Asbrink et al. 2000). Carvedilol did not affect other reactions dependent on NO, e.g. spontaneous of formyl-methionyl-leucyl-phenylalanine-stimulated polymorphonuclear leucocyte migration or hpoxin A4-, fMLP-, or A23187-induced neutrophil cytotoxicity for human umbiUcal vein endothehal cells. Thus, these effects point to the possibility that carvedilol modulates the NADPH oxidase of polymorphonuclear leucocytes but leaves the nitric oxide synthase of phagocytes intact. Carvedilol exerted poor reactivity toward phenoxyl, alkoxyl, and per-oxyl radicals in acetonitrile solution nor did it show an appreciable antioxidant effect against either the peroxyl radical-induced oxidation of methyl Unole-... 

Sharma ML, Khajuria A, Kaul A, Singh S, Singh GB, Atal CK (1988) Effect of salai gug-gal tx-Boswellia serrata on cellular and humoral responses and leucocyte migration. Agents Action 24 161-164... 

CAi z, GAO c, o L, XING K (2010), Bipolar properties of red seabream (Pagrus major) transforming growth factor-beta in induction of the leucocytes migration . Fish Shellfish Immunol, 28, 695-700. 

The administration of IL-ip-derived peptides to rainbow trout by i.p. injection induced reduced mortality of fish when exposed to VHSV 2 days later (Peddie et al. 2003). The peptide also induced leucocyte migration into the peritoneal cavity 1-3 days post-injection. The role of IL-ip as an adjuvant was also investigated in carp after i.p. injection of killed A. hydrophila... 

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