Kinase cancers

BCR-ABL tyrosine kinase Cancer Point mutation causes resistance to STI-571 compound 21... 

Kleuser, B., Cuvillier, O., and Spiegel, S., 1998, la,25-dihydroxy vitamin D3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase. Cancer Res. 

Zheng, F. F., S. D. Kuduk, G. Chiosis, P. N. Munster, L. Sepp-Lorenzino, S. J. Danishefsky, and N. Rosen. Identification of a geldanamycin dimer that induces the selective degradation of HER-family tyrosine kinases. Cancer Res. 60 2090-4.2000a. 

Rabindran SK, Discafani CM, Rosljord EC et al. Antitumor activity of HKI-272, an orally active, irreversible inhibitor of the HER-2 tyrosine kinase. Cancer Res 2004 64 3958-3965. 

Rodriguez, C.O., Jr. Mitchell, B.S. Ayres, M. Eriksson, S. Candhi, V. Ara-binosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. Cancer Res., 62, 3100-3105 (2002)... 

She QB, Bode AM, Ma WY, Chen NY, Dong Z. 2001. Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase. Cancer Res 61 1604-1610. 

O. Wildner, R. M. Blaese, and J. C. Morris, Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase, Cancer Res. 59 410 (1999). 

Syljuasen RG, Jensen S, Bartek J, Lukas J. Adaptation to the ionizing radiation-induced G2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and Polo-like kinase 1 kinases. Cancer Res. 2006 66 10253-10257. 

Moyer JD, Barbacci EG, Iwata KK, Arnold L, Boman B, et al. 1997. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 57 4838 18... 

Hattori Y, Maitani Y (2005) Folate-linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase. Cancer Gene Ther 12 796-809... 

Kurinna, S.M., Tsao, C.C., Nica, A.F., Jiffar, T., and Ruvolo, P.P. (2004). Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase. Cancer Res 64, 7852-6. 

Hirata, A., S. Ogawa, T. Kometani, T. Kuwano, S. Naito, M. Kuwano, and M. Ono. ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase. Cancer Res 62 2554-60, 2002. 

Mizuguchi H, Hayakawa T (2002). Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase. Cancer Gene Ther. 9 236-242. 

Holmes-McNary M, Baldwin AS. Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase. Cancer Res 2000 60 3477-3483. 

Yin, Z., Ivanov, V.N., Habelhah, H., Tew, K., and Ronai, Z., Glutathione S-transferase p elicits protection against H202-mduced cell death via coordinated regulation of stress kinases. Cancer Res., 60, 4053M057, 2000. 

Sunil KM, Nand KS, Robert AN et al (2000) Oleandrin suppresses activation of nuclear transcription factor-KB, activator protein-1, and c-Jun NH2-terminal kinase. Cancer Res 60 3838-3847... 

Kang HG, Jenabi JM, Zhang J. et al. E-cadherin cell-cell adhesion in ewing tumor cells mediates suppression of anoikis through activation of the ErbB4 tyrosine kinase. Cancer Res 2007 67 3094-105. 

Brockman RW, Cheng Y, Schabel FM Jr, Montgomery JA (1980) Metabolism and chemotherapeutic activity of 9-p-D-arabinofuranosyl-2-fluoroadenine against murine leukemia L1210 and evidence for its phosphorylation by deoxycytidine kinase. Cancer Res 40 3610-3615... 

Bettayeb, K., Tirado, O.M., Marionneau-Lambot, S Eerandin, Y, Lozach, O., Morris, J.C., Mateo-Lozano, S., Drueckes, P Schachtele, C., Kubbutat, M.H.G., Liger, F., Marquet, B., Joseph, B Echalier, A., Endicott, J.A., Notario, V., and Meijer, L (2007) Meriolins, a new class of cell death-inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases. Cancer Res., 67, 8325-8334. 

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