Breast cancer phosphatidylinositol-3-kinase

Liu, X., Shi, Y., Giranda, V. L. and Luo, Y., Inhibition of the phosphatidylinositol 3-kinase/ Akt pathway sensitizes MDA-MB468 human breast cancer cells to cerulenin-induced apoptosis. Mol Cancer Ther 5 (2006) 494-501. 

Way TD, Kao MC, Lin JK (2004a) Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neu-overexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Akt-... 

Steenbergh, J.S. Sussenbach. Mitogenic Signaling of Insulin-Like Growth Factor I in MCF-7 Human Breast Cancer Cells Requires Phosphatidylinositol 3-kinase and is Independent of Mitogen-Activated Protein Kinase. 272 31163—31171... 

Resveratrol (Fig. 4), a bioactive stilbenoid found in nuts and wine from red grapes, has antioxidant, anti-thrombotic, and anti-inflammatory properties (Labinskyy et al, 2006). It also inhibits carcinogenesis in animal models of breast cancer (Whitsett et al, 2006). Muscadine grape skin extract causes phosphatidylinositol 3-kinase Akt-dependent apoptosis in prostate cancer cell Unes, but not prostate epithelial cells (Hudson et al, 2007). This is different from res-veratrol s effects in the prostate cancer cells which are concentrated on inhibition of the... 

---