Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Development kidney

Thorotrast (colloidal Th02) was once used as a radiopaque agent in medicine (see Radiopaques). Its injection in a dose of 2.0—15.0 g caused rises in body temperature, nausea, and injury to tissues at the injection site, followed by anemia, leukopenia, and impairment of the reticuloendothehal system. After intravenous adrninistration, thorotrast particles are taken up by reticuloendothehal cells of the fiver and spleen. Thorotrast is virtually not eliminated from the body (91). Between 1947 and 1961, 33 cases of cancer of the fiver, larynx, and bronchi and sarcoma of the kidneys, developing from 6 to 24 years after thorotrast administering, have been described in the literature (92). [Pg.44]

GDNF Family - GDNF, NRTN, ARTN, and PSPN RET Alternative splicing results in three isoforms Required for enteric neuron development, kidney development, and spermatogenesis... [Pg.566]

Since angiotensin II is important for kidney development in mammals, ACE inhibitors and other dtugs interfering with RAS should not be given during pregnancy. [Pg.1068]

As with ACE inhibitors, renin inhibitors should not be used in pregnancy, specifically the second and third trimesters, during which they will interfere with fetal kidney development. [Pg.318]

How these interactions alert the genome of the mesenchyme to start transcribing the elements necessary for differentiation into nephrons is not known. However, the early events involve the expression of WT1, a transcription factor critical for early kidney development. WT1... [Pg.41]

Despite the high rate of proliferation, there is also significant apoptosis in the kidney. Apoptosis is associated with three processes of kidney development. The first is during early nephron formation, perhaps as a way to get rid of cells that did not undergo the mesenchyme-epithelial transition. The second phase of apoptosis sculpts the glomeruli, and the third phase occurs later in the medulla and renal pelvis. Mice that overexpress p53 have excessive cell death and develop kidneys that are smaller than normal. Mice that are null for the bcl-2 gene have excessive apoptosis early in renal development, followed by hyperproliferation. This leads to the development of cystic kidneys. [Pg.44]

Kidney development can be used again here to illustrate the kinds of events that occur during organ maturation, which takes place during fetal and postnatal development. While the induction of the organ and formation of its basic structure are initiated in the embryonic period, differentiation of the nephrons is not complete until term in humans, and not until the 2nd week postnatally in rodents. [Pg.47]

Gomez RA, Sequeira Lopez ML, Fernandez L, Chernavvsky DR, Norwood VF (1999) The maturing kidney development and susceptibility. Ren Fail, 21(3-4) 283-291. [Pg.264]

GDNF, glial-cell-line-derived neurotrophic factor Survival of neurons kidney development... [Pg.103]

Choline deficiency produces renal as well as hepatic damage- This damage takes the form of degeneration of the renal tubules and bleeding, which may lead to death of the animal within 1 week of feeding the diet (Keith and Tryphonas, 1978). Under certain conditions, the liver and kidneys develop scar tissue. Cbxho-sEs is a term used to describe the conversion of normal tissues to scarlike fibrous tissues. [Pg.318]

ThedieckC, KuczykM, KlingelK, Steiert I, Muller CA, Klein G. Expression of Ksp-cadherin during kidney development and in renal cell carcinoma British Journal of Cancer. 2005 92,2010-2017. [Pg.127]

Angiotensin-converting enzyme (ACE) inhibitors have improved survival dramatically in patients with renal involvement and improve outcomes in patients with disease-associated pulmonary hypertension or myocardial involvement. Patients with sclerosis of the kidneys develop hypertension, leading to a renal crisis. In these patients, plasma renin activity and angiotensin concentrations can be more than twice normal. Renal involvement should be anticipated... [Pg.1592]

Merlet-Benichou, C. (1999) Influence of fetal environment on kidney development. International Journal of Developmental Biology, 43, 453 156. [Pg.429]

Dekel B, Amariglio N, Kaminski N, et al. En-graftment and differentiation of human meta-nephroi into functional mature nephrons after transplantation into mice is accompanied by a profile of gene expression similar to normal human kidney development. J. Am. Soc. Nephrol. 2002 13(4) 977-990. [Pg.379]

Lyons JP, Miller RK, Zhou X, Weidinger G, Dtaoo T, Denayta- T, Park JI, Ji H, Hong JY, Li A, Moon RT, Jones EA, Vleminckx K, Vize PD, McCrea PD. Requirement of Wnt/beta-catenin signaling in pronephtic kidney development Mech Dev. [Pg.694]

Protocols Designed to Mimic Embryonic Kidney Development... [Pg.369]

Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, Oliver G, McMahon AP. 2008. Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell 3(2) 169-181. [Pg.381]

Morizane R, Lam AQ, Freedman BS, Kishi S, Valerius MT, Bonventre JV. 2015. Nephron organoids derived from human pluripotent stem cells model kidney development and injury. Nat Biotechnol 33(11) 1193-1200. [Pg.382]

Mugford JW, Sipila P, Kobayashi A, Behringer RR, McMahon AP. 2008a. Hoxdll specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo. Dev Biol 319(2) 396-405. [Pg.382]

Nishinakamura R, Takasato M. 2005. Essential roles of SaUl in kidney development Kidney Int 68(5) 1948-1950. [Pg.382]

Vainio S, Lin Y. 2002. Coordinating early kidney development lessons from gene targeting. Nat Rev Genet 3(7) 533-543. [Pg.383]


See other pages where Development kidney is mentioned: [Pg.104]    [Pg.17]    [Pg.40]    [Pg.41]    [Pg.43]    [Pg.39]    [Pg.337]    [Pg.53]    [Pg.113]    [Pg.22]    [Pg.23]    [Pg.364]    [Pg.366]    [Pg.16]    [Pg.367]    [Pg.369]    [Pg.369]    [Pg.369]    [Pg.371]    [Pg.374]    [Pg.375]    [Pg.375]   
See also in sourсe #XX -- [ Pg.55 , Pg.56 ]




SEARCH



© 2024 chempedia.info