Epithelial—mesenchymal transition

Lee TK, Man K, Poon RT, Lo CM, Yuen AP, Ng 10 et al (2006b). Signal transdncers and activators of transcription 5b activation enhances hepatocellnlar carcinoma aggressiveness through induction of epithelial-mesenchymal transition. Cancer Res 66 9948-9956. 

Lee TK, Poon RT, Yuen AP, Ling MT, Kwok WK, Wang XH et al (2006c). Twist overexpression correlates with hepatocellnlar carcinoma metastasis through induction of epithelial-mesenchymal transition. Clin Cancer Res 12 5369- 5376. 

Li Q, Chen C, Kapadia A et al (2011) 3D models of epithelial-mesenchymal transition in breast cancer metastasis high-throughput screening assay development, validation, and pilot screen. J Biomol Screen 16 141-154... 

Moreno-Bueno G, Cubillo E, Sarrio D et al. Genetic profiling of epithelial cells expressing e-cadherin repressors reveals a distinct role for snail, slug and e47 factors in epithelial-mesenchymal transition. Cancer Res 2006 66(19) 9543-9556. 

Slattery C, Campbell E, McMorrowT, and Ryan MP. Cyclosporine A-induced renal fibrosis a role for epithelial-mesenchymal transition. Am J Pathol 167 395-407, 2005. 

TGF-p. Strategies to block the process of epithelial-mesenchymal transition are being explored for future therapeutic targets in CKD, ... 

ABC ATP CDX CNT ENT EMT GIT GO NCE PEPT1 PMT QSAR SAR SLC ATP-binding cassette Adenosine 5 -triphosphate Caudal-type homeobox transcription factor Concentrative nucleoside transporter Equilibrative nucleoside transporter Epithelial-mesenchymal transition Gastrointestinal tract Gene ontology New chemical entity Di/tri-peptide transporter 1 Pharmacogenetics of Membrane Transporters Project Quantitative structure-activity relationship Structure-activity relationship Solute carriers (SLCs)... 

Thiery, J.P. and Sleeman, J.P. (2006) Complex networks orchestrate epithelial—mesenchymal transitions. Nature Reviews. Molecular Cell Biology,... 

Kiemer, A.K., Takeuchi, K. and Quinlan, M.P. (2001) Identification of genes involved in epithelial-mesenchymal transition and tumor progression. Oncogene, 20 (46), 6679-6688. 

Yamashita, S., Miyagi, C., Fukada, T., Kagara, N., Che, Y.S. and Hirano,T. (2004) Zinc transporter LIVI controls epithelial-mesenchymal transition in... 

Onoue T., Uchida D., Begum N. M., et al.(2006) Epithelial-mesenchymal transition induced by the stromal cell-derived factor-1/CXCR4 system in oral squamous cell carcinoma cells. Int J Oncol., 29, 1133-8. 

Cano, A., Perez-Moreno, M.A., Rodrigo, I., Locascio, A., Blanco, M.J., del Barrio, M.G., Portillo, F., Nieto, M.A. 2000. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2, 76-83. 

Exposure of OK and NRK-25E cells to ochratoxin A in the presence of an inhibitor of ERK 1/2 showed that the toxicity of ochratoxin A, as measured by cell number, protein, epithelial tightness, apoptosis and necrosis, was increased. Biomarkers of inflammation, fibrosis and epithelial mesenchymal transition were also enhanced in the presence of the inhibitor of ERK 1/2, compared with ochratoxin A alone. The authors speculated that the toxicity of ochratoxin A may be influenced by the balance between the profibrotic ERK 1/2 and the antifibrotic JNK and p38, which are not affected by inhibition of ERK 1/2, and that naturally occurring inhibitors of ERK 1/2, such as anthocyanidins, may amplify the effects of ochratoxin A (Sauvant et al., 2005c). 

Sureban SM, May R, Lightfoot SA, Hoskins AB, Lerner M, Brackett DJ, Postier RG, Ramanujam R, Mohammed A, Rao CV, Wyche JH, Anant S, Houchen CW. DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism. Cancer Res. 2011 71 2328-38. 

Luo WR, Chen XY, Li S Y, Wu AB, Yao KT. Neoplastic spindle cells in nasophar5mgeal carcinoma show features of epithelial-mesenchymal transition. Histopathology. 2012 61 113-22. 

Kurahara H, Takao S, Maemura K, Mataki Y, Kuwahata T, Maeda K, Ding Q, Sakoda M, Lino S, Ishigami S, Ueno S, Shinchi H. Natsugoe S. Epithelial-mesenchymal transition and mesenchymal-epithelial transition via regulation of ZEB-1 and ZEB-2 expression in pancreatic cancer. J Surg Oncol. 2012 105 655-61. 

Sun Y, Wang BE, Leong KG, Yue P, Li L, Jhunjhunwala S, Chen D, Seo K, Modtusan Z, Gao WQ, Settleman J, Johnson L. Androgen deprivation causes epithelial-mesenchymal transition in the prostate implications for androgen-deprivation therapy. Cancer Res. 2012 72 527-36. doi 10.1158/0008-5472.CAN-l 1-3004. 

Wang Q, Ma C, Kemmner W. Wdi66 is a novel marker for risk stratification and involved in epithelial-mesenchymal transition of esophageal squamous cell carcinoma. BMC Cancer. 2013 13 137. doi 10.1186/1471-2407-13-137. 

Jiang YS, Jiang T, Huang B, Chen PS, Ouyang J. 2013. Epithelial-mesenchymal transition of renal tubules divergent processes of repairing in acute or chronic injury Med Hypotheses 81(l) 73-75. 

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