Insulin-like growth factor binding proteins

IGFBP-3 insulin-like growth factor binding protein 3... 

Clemmons, D. R., W. H. Busby, T. Arai et al. 1995. Role of insulin-like growth factor binding proteins in the control of IGF actions. Prog Growth Factor Res 6(2-4) 357-366. 

Holmes, M. D., M. N. Poliak, W. C. Willett, and S. E. Hankinson. 2002. Dietary correlates of plasma insulinlike growth factor I and insulin-like growth factor binding protein 3 concentrations. Cancer Epidemiol Biomarkers Prev 11 (9) 852—861. 

Karas, M., M. Danilenko, D. Fishman et al. 1997. Membrane-associated insulin-like growth factor-binding protein-3 inhibits insulin-like growth factor-I-induced insulin-like growth factor-I receptor signaling in ishikawa endometrial cancer cells. J Biol Chem 272(26) 16514—16520. 

Liu, C., F. Lian, D. E. Smith, R. M. Russell, and X. D. Wang. 2003. Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets. Cancer Res 63(12) 3138-3144. 

Vrieling, A., D. W. Voskuil, J. M. Bonfrer et al. 2007. Lycopene supplementation elevates circulating insulin-like growth factor binding protein-1 and -2 concentrations in persons at greater risk of colorectal cancer. Am J Clin Nutr 86(5) 1456-1462. 

Graydon, R, SE Gilchrist, IS Young, U Obermuller-Jevic, O Hasselwander, and JV Woodside. 2007. Effect of lycopene supplementation on insulin-like growth factor-1 and insulin-like growth factor binding protein-3 a double-blind, placebo-controlled trial. EurJ Clin Nutr 61(10) 1196-2000. 

Miyata, Y, H Sakai, T Hayashi, and H Kanetake. 2003. Serum insulin-like growth factor binding protein-3/ prostate-specific antigen ratio is a useful predictive marker in patients with advanced prostate cancer. Prostate 54 125-132. 

Furstenberger, G. and Senn, H. 2002. Insulin like growth factors and cancer. Lancet Oncology, 3(5), 298-302. Kostecka, Z. and Blahovec, J. 2002. Animal insulin-like growth factor binding proteins and their biological functions. Veterinami Medicina 47(2-3), 75-84. 

Huynh H, Poliak M (1994) Uterotrophic actions of estradiol and tamoxifen are associated with inhibition of uterine insulin-like growth factor binding protein 3 gene expression. Cancer Res 54(12) 3115—3119... 

Hembree JR, Agarwal C, Beard RL, Chandraratna RA, and Eckert R [1996] Retinoid X receptor-specific retinoids inhibit the ability of retinoic acid receptor-specific retinoids to increase the level of insulin-like growth factor binding protein-3 in human ectocervical epithelial cells. Cancer Res 56 1794-1799... 

Hembree JR, Lambert A, Agarwal C, Efimova T, and Eckert RL [1999] Insulin-like growth factor binding protein-3 does not mediate the interferon-dependent... 

A small number of children with growth failure have severe IGF-1 deficiency that is not responsive to exogenous GH. Causes include mutations in the GH receptor and development of neutralizing antibodies to GH. In 2005, the FDA approved mecasermin for treatment of severe IGF-1 deficiency that is not responsive to GH. Mecasermin is a complex of recombinant human IGF-1 (rhIGF-1) and recombinant human insulin-like growth factor-binding protein-3 (rhIGFBP-3). 

Cohen P, Graves HC, Peehl DM, Kamarei M, Giudice LC, Rosenfeld RG. Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma. J Clin Endocrinol Metab 1992 75 1046-1053. 

C18. Conover, C. A., Perry, J. E., and Tindall, D. J., Endogenous cathepsin D-mediated hydrolysis of insuline-like growth factor-binding proteins in cultured human prostatic carcinoma cells. J. 

D6. Damon, S. E., Maddison, L., Ware, J. L., and Plymate, S. R., Overexpression of an inhibitory insulin-like growth factor binding protein (IGFBP), IGFBP-4, delays onset of prostate tumor formation. Endocrinology 139, 3456-3464 (1998). 

F5. Figueroa, J. A., De Raad, S., Tadlock, L., Speights, V. O., and Rinehart, J. J., Differential expression of insulin-like growth factor binding proteins in high versus low Gleason score... 

Salobir, B., Prezelj, J., Meden-Vrtovec, H., Kocijanic, A., and Osredkar, J., Insulin-like growth factor binding protein-3 (IGFBP-3) serum concentrations and ovarian responsiveness in in-vitro fertilization. Hum. Reprod. 11, 2208-2210 (1996). 

Kostecka Y, Blahovec J. Insulin-like growth factor binding proteins and their functions. Endocr Regul 1999 33 9(H4. 

Shmueli, E., Miell, J.R, Stewart, M., Alberti, K.GJVIJVI., Record, C.O. High insulin-like growth factor binding protein 1 levels in cirrhosis link with insulin resistance. Hepatology 1996 24 127-133... 

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