Immunohistochemical expression

Chalabi, N, L Delort, S Satih, P Dechelotte, YJ Bignon, and DJ Bemard-Gallon. 2007. Immunohistochemical expression of RARalpha, RARbeta, and Cx43 in breast tumor cell lines after treatment with lycopene and correlation with RT-QPCR. J Histochem Cytochem 55(9) 877-883. 

Pusztaszeri M, Seelentag W, Bosman FT. Immunohistochemical expression of endothelial markers CD31, CD34, von Willebrand Factor, and Fli-1 in normal human tissues./. Histochem. Cytochem. 2006 54 385-395. 

Albaric, O., Bret, L., Amardeihl, M., and Delverdier, M. 2001. Immunohistochemical expression of p53 in animal tumors a methodological study using four anti-human p53 antibodies. Histol. Histopathol. 76 113—121. 

Iczkowski, K. A., Cheng, L., Crawford, B. G., and Bostwick, D. G. 1999. Steam heat with an EDTA buffer and protease digestion optimizes immunohistochemical expression of basal cell-specific antikeratin 34pE12 to discriminate cancer in prostatic epithelium. Mod. Pathol. 72 1-4. 

Schmitt, F. C., Soares, R., Cimes, L., and Seruca, R. 1998. p35 in breast carcinomas Association between presence of mutation and immunohistochemical expression using a semiquantitative approach. Pathol. Res. Pract. 797 815-819. 

Fig. 3. Immunohistochemical expression of (a) hK7 by the epithelium of eccrine glands of the skin (monoclonal antibody, clone 73.2), (b) hK13 by the epithelium of the bronchus (monoclonal antibody, clone IIC1), (c) hK5 by the ductal epithelium of the parotid gland (polyclonal antibody), (d) hK7 by the esophageal glands (monoclonal antibody, clone 73.2), (e) hK13 by the gastric mucosa (monoclonal antibody, clone 2-17), (f) hK6 by the large intestine mucosa (polyclonal antibody), (g) hK10 in an islet of Langerhans in the pancreas (monoclonal antibody, clone 5D3), (h) hKll by the epithelium of the urinary tubuli (monoclonal antibody), (i) hKll by a papillary renal cell carcinoma (monoclonal antibody).

Fig. 5. Immunohistochemical expression of (a) hK14 by the ovarian surface epithelium (polyclonal antibody), (b) hK14 by a cystadenocarcinoma of the ovary (polyclonal antibody),...

Petraki CD, Gregorakis AK, Vaslamatzis MM, Papanastassiou P, Yousef GM, Diamandis EP. The immunohistochemical expression of human kallikreins 5, 6, 10 and 11 in renal cell carcinoma. Correlation with several prognostic factors. Proc AACR 2003 44 1077, abstract 5412. 

Zidar N, Dolenc-Strazar Z, Jeruc J, Stajer D. Immunohistochemical expression of activated caspase-3 in human myocardial infarction. Virchows Archiv 2006 448 75-79. 

PrakasaBabuP., YoshidaY., SuM., SeguraM., KawamuraS., and Yasui N. (2000) Immunohistochemical expression of Bcl-2, Bax and cytochrome c following focal cerebral ischemia and effect of hypothermia in rat. Neurosci. Lett. 291,196-200. 

The p53 protein can also been measured by other methods. The LIA method is intended for measurement of the p53 protein in tumor cytosols normally prepared for the routine biochemical measurement of the oestrogen and progesteron receptor status. The LIA method has been demonstrated to be useful and to give prognostic information in a breast cancer material (34). The principal laboratory steps are outlined in Table 3. The LIA measurement of the p53 protein has been compared with immunohistochemical expression and cDNA-based sequencing on more than 200 primary breast cancers (Norberg et al., unpublished data). In brief, the LIA technique seems to have the same principal limitations as the immunohistochemical determination, and the sensitivity and specificity is no better than with immunohistochemical determination. 

Pietatd GE, Arrese-Estrada J, Pietatd-Ftanchimont C, et al. Immunohistochemical expression of galactomannan in the cytoplasm of phagocytic cells during invasive aspergillosis. Am J Clin Pathol. 1991 96 373-376. 

Rakheja D, Molberg KH, Roberts CA, et al. Immunohistochemical expression of beta-catenin in solitary fibrous tumors. Arch Pathol Lab Med. 2005 129 776-779. 

Pierard-Franchimont C, Letawe C, Nikkels AF, et al. Patterns of the immunohistochemical expression of melanoma-associated antigens and density of CD45R0+ activated T-lymphocytes and LI-protein-positive macrophages in primary cutaneous melanomas. Int J Mol Med. 1998 2 721-724. 

Nikitakis NG, Tosios KI, Papanikolaou VS, et al. Immunohistochemical expression of cytokeratins 7 and 20 in malignant salivary gland tumors. Mod Pathol. 2004 17 407-415. 

Giwercman A, Andrews PW, Jorgensen N, et al. Immunohistochemical expression of embryonal marker TRA-1-60 in carcinoma in situ and germ cell tumors of the testis. Cancer. 1993 72 1308-1314. 

Franchi A, Massi D, Palomba A, et al. CDX-2, cytokeratin 7 and cytokeratin 20 immunohistochemical expression in the differential diagnosis of primary adenocarcinomas of the sinonasal tract. Virchows Arch. 2004 445(l) 63-67. 

Kimura N, Pilichowska M, Okamoto H, et al. Immunohistochemical expression of chromogranins A and B, prohormone convertases 2 and 3, and amidating enzyme in carcinoid tumors and pancreatic endocrine tumors. Mod Pathol. 2000 13 140-146. 

Ltan Lt, Landreneaux RJ, Santucci TS, et al. Prognostic value of immunohistochemical expression of p53, HER-2-neu and bcl-2 in stage I non-small cell lung cancer. Hum Pathol. 2002 33 105-110. 

DiLoreto G, DiLauro V, Puglisi F, et al. Immunohistochemical expression of tissue specific transcription factor-1 in lung carcinoma. J Clin Pathol. 1997 50 30-32. 

Pinkus GS, Lones MA, Matsumura F, et al. Langerhans cell histiocytosis immunohistochemical expression of fascin, a dendritic cell marker. Am J Clin Pathol. 2002 118 335-343. 

Lau SK, Chu PG, Weiss LM. Immunohistochemical expression of Langerin in Langerhans cell histiocytosis and non-Langerhans cell histiocytic disorders. Am J Surg Pathol. 2008 32 615-619. 

Bruwer M, Schmid KW, Senninger N, Schurmann G. Immunohistochemical expression of P53 and oncogenes in trlcer-ative colitis-associated colorectal carcinoma. World J Surg. 2002 26 390-396. 

Vang R, Gown AM, Wu LS, et al. Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary comparison with CK20 and correlation with coordinate expression of CK7. Mod Pathol. 2006 19 1421-1428. 

Takashima M, Ueki T, Nagai E, et al. Carcinoma of the ampulla of Vater associated with or without adenoma a clinico-pathologic analysis of 198 cases with reference to p53 and Ki-67 immunohistochemical expressions. Mod Pathol. 2000 13 1300-1307. 

Immunohistochemical expression of PAX2 has been demonstrated in CCRCC, PRCC, and ChRCC subtypes, as well as collecting duct carcinoma and MTSC renal tumors. 

Among non-GCTs, AFP is a sensitive serum marker for the diagnosis and surveillance of hepatocellular carcinoma. However, immunohistochemical expression of AFP in HCC tissue is limited to a minority of cases. 

Lane Z, Hansel DE, Epstein JI. Immunohistochemical expression of prostatic antigens in adenocarcinoma and villous adenoma of the urinary bladder. Am J Surg Pathol. 2008 32 1322. 

Vang R, Gown AM, Barry TS, et al. Gytokeratins 7 and 20 in pti-mary and secondary mucinous tumors of the ovary analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases. Am J Surg Pathol. 2006 30 1130. 

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