IARC

IARC, International Agency for Research on Cancer. Monographs on the Evaluation of Carcinogenic Risks of Chemicals to Humans. Suppl 7, 201 (1987). [Pg.308]

IARC. 1983. lARC Monographs on the evaluation of the carcinogenic risk of chemicals to humans. Vol. 30. Miscellaneous Pesticides. Lyon, France International Agency for Research on Cancer, World Health Organization. [Pg.213]

IARC Monographs International Agency for Research on Cancer Lyon, France, 1985 Vol. 36, pp 75-97. [Pg.353]

IARC. 1989. Tumour development following internal exposures to radionuclides during perinatal period. Richland, WA International Agency for Research on Cancer. [Pg.242]

IARC. 1997. Overall evaluations of carcinogenicity to humans. World Health Organization, Lyon, France. [Pg.149]

The Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), and EPA have not classified mineral oil hydraulic fluids, polyalphaolefin hydraulic fluids, and organophosphate ester hydraulic fluids for carcinogenic effects. [Pg.19]

Mineral Oil and Polyalphaolefin Hydraulic Fluids. No studies were located regarding metabolism in humans or animals after exposure to mineral oil hydraulic fluids or polyalphaolefin hydraulic fluids. It should be noted, however, that hydrocarbons found in mineral oils generally are not expected to undergo extensive metabolism in animals or humans (Cannon 1940 IARC 1984). It may be speculated that polyalphaolefins may undergo limited metabolism of a similar nature. [Pg.171]

Mineral Oil Hydraulic Fluids. The mechanism whereby mineral oil hydraulic fluids may enter the blood from the lungs, skin or gastrointestinal tract is not known. In general, mineral oils and other petroleum-derived materials are expected to be absorbed only to a limited extent by the lungs, skin, and the gastrointestinal tract (IARC 1984 Klein and Simon 1986), but data monitoring mineral oil hydraulic fluid components in the blood of animals or humans after exposure were not located. [Pg.180]

Mineral Oil Hydraulic Fluids. No information identifying the major components of mineral oil or water-in-oil hydraulic fluids was located in the available literature, nor was any information located that described how the emulsifiers and other components in water-in-oil emulsion hydraulic fluids alter the environmental properties of the mineral oils contained in them. The carbon number range present in mineral oil hydraulic fluids probably is from C15 to C50 (IARC 1984 Shubkin 1993 Wills 1980). If automatic transmission fluids are typical of the mineral oil content in a hydraulic fluid, then mineral oil hydraulic fluids contain -90% mineral oil (Abdul et al. 1990 Papay 1989,1991). Therefore, the transport and partitioning of these hydrocarbons will largely account for the environmental behavior of mineral oil hydraulic fluids. Typical transport and partitioning information for hydrocarbons in this range is presented below this information is indicative of the transport and partitioning of mineral oils present in hydraulic fluids. [Pg.297]

IARC. 1984. Carbon blacks, mineral oils, (lubricant base oils and derived products) and some nitroarenes. IARC Monogr Eval Carcinog Risk Chem Hum 33 86-167. [Pg.341]

Cadet J (1994) In Hemminki K, Dipple A, Shuker DEG, Kadlubar FF, Sagerback D, Barstch D (eds) DNA Adducts Identification and Biological Significance. International Agency for Research on Cancer. IARC Scientific Publications, Lyon No 125 p 245... [Pg.32]

The information available regarding the association of occupational exposure to lead with increased cancer risk is generally limited in its usefulness because the actual compound(s) of lead, the route(s) of exposure, and level(s) of lead to which the workers were exposed were often not reported. Furthermore, potential for exposure to other chemicals including arsenic, cadmium, and antimony occurred, particularly in lead smelters, and smoking was a possible confounder (Cooper 1976 IARC 1987). These studies, therefore, are not sufficient to determine the carcinogenicity of lead in humans, and the following discussion is restricted to the most comprehensive of these studies. [Pg.128]

The International Agency for Research on Cancer (IARC 1987) concluded that the evidence for carcinogenicity of lead and inorganic lead compounds was inadequate in humans and sufficient in animals. IARC (1987) classified lead and inorganic lead compounds in IARC Group 2B, possible human carcinogen. The Department of Health and Human Services (DHHS) has determined that lead acetate and phosphate may reasonably be anticipated to be carcinogens based on sufficient evidence from animal studies, but inadequate evidence from human studies (NTP 1994). [Pg.307]

IARC Carcinogenic classification Elemental lead and inorganic lead compounds Organolead Group 2Ba Group 3b IARC 1987... [Pg.468]

Landolph JR (1985) Chemical transformation of C3H/10T1/2 Cl 8 mouse embryo cells historical background, assessment of the transformation assay and evaluation and optimization of the transformation assay protocol. In IARC Scientific Publication No 67, pp 185-198... [Pg.205]

Schechtman LM (1985) BALB/c 3T3 cell transformation protocols, problems and improvements. In Kakunaga T, Yamasaki H (eds) Transformation assay of established cell lines mechanisms and application. IARC Scientific Publications 67, Lyon, pp 165-181... [Pg.205]

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