Agency for Research on Cancer IARC

International Agency for Research on Cancer, IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans Some N-Nitroso Compounds, Vol 17, lARC, Lyon, France, 1978 p-263, 287. 

The Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), and EPA have not classified mineral oil hydraulic fluids, polyalphaolefin hydraulic fluids, and organophosphate ester hydraulic fluids for carcinogenic effects. 

Cadet J (1994) In Hemminki K, Dipple A, Shuker DEG, Kadlubar FF, Sagerback D, Barstch D (eds) DNA Adducts Identification and Biological Significance. International Agency for Research on Cancer. IARC Scientific Publications, Lyon No 125 p 245... 

The International Agency for Research on Cancer (IARC 1987) concluded that the evidence for carcinogenicity of lead and inorganic lead compounds was inadequate in humans and sufficient in animals. IARC (1987) classified lead and inorganic lead compounds in IARC Group 2B, possible human carcinogen. The Department of Health and Human Services (DHHS) has determined that lead acetate and phosphate may reasonably be anticipated to be carcinogens based on sufficient evidence from animal studies, but inadequate evidence from human studies (NTP 1994). 

International Agency for Research on Cancer (IARC). 1976. IARC monographs on the evaluation of the carcinogenic risk of chemicals to man cadmium, nickel, some epoxides, miscellaneous industrial chemicals and general considerations on volatile anaesthetics. Volume 11. World Health Organization, IARC, Lyon, France. 306 pp. 

Liver tumors developed in mice that were orally exposed to hexachloroethane for their whole lifetime. Tumors of this kind are common in mice. Hexachloroethane will not necessarily have the same effect on people. Male rats that were exposed to hexachloroethane for their lifetime developed kidney tumors. This type of tumor is not found in people, so it is unlikely that exposure to hexachloroethane would cause you to develop cancer of the kidney. The Department of Health and Human Services has determined that hexachloroethane may reasonably be anticipated to be a carcinogen (can cause cancer). The International Agency for Research on Cancer (IARC) has determined that hexachloroethane is not classifiable as to its carcinogenicity in people. EPA has determined that hexachloroethane is a possible human carcinogen. 

VX is not listed by the International Agency for Research on Cancer (IARC), American Conference of Governmental Industrial Hygienists (ACGIH), Occupational Safety and Health Administration (OSHA), or National Toxicology Program (NTP) as a carcinogen. 

There is no evidence that exposure to //-hexane increases the risk of cancer in people. No reliable information is available on whether //-hexane causes cancer in animals. In an animal experiment with commercial hexane (which contains //-hexane), an increase in liver cancer was found in female mice after exposure for 2 years. No increase was found in male mice or in rats of either sex. Commercial hexane is a mixture, and we do not know what parts of the mixture caused the cancer in the female mice. //-Hexane has not been characterized for carcinogenicity by the Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), or the Environmental Protection Agency (EPA). 

We do not know for sure whether either mirex or chlordecone causes cancer in humans. The Department of Health and Human Services (DHHS) has determined that mirex and chlordecone may reasonably be expected to be carcinogens. The International Agency for Research on Cancer (IARC) has determined that mirex and chlordecone are possibly carcinogenic to humans. The EPA has not classified mirex or chlordecone as to carcinogenicity. In rodents, mirex causes liver, adrenal, and blood cancer. Chlordecone also causes liver cancer in rodents, but because of problems with these animal studies, more information is necessary to be sure. 

International Agency for Research on Cancer (IARC) Classifications ... 

It is not known if phenol causes cancer in humans. However, cancer has been shown to occur in mice when phenol was applied to the skin several times each week during the whole lifetime of the animal. When it is applied in combination with certain cancer-causing chemicals, a higher rate of cancer occurs than when the carcinogens are applied alone. Phenol did not cause cancer in mice or rats when they drank water containing phenol for 2 years. The International Agency for Research on Cancer (IARC) considers phenol not classifiable as to its carcinogenicity in humans. 

Neubert D (1980) Teratogenicity Any relationship to carcinogenicity In Montesano R, Bartsch H, Tomatis L, Davis Wed. Molecular and cellular aspects of carcinogen screening tests. Lyon, International Agency for Research on Cancer (IARC Scientific Publications No. 27). 

The IOM committee decided to disregard the many questions and criticisms about Hardell s studies by many other reviewers. U.S. EPA, in its massive 2000 review of risks from dioxin,28 does not rely on Hardell s studies, and the International Agency for Research on Cancer (IARC),29 and the European Commission30 and World Health Organization (WHO)31 disregard them. 

---