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Metal (or Process Involving Metal Exposure) Evidence for Carcinogenicity in Humans Evidence for Carcinogenicity in Animals IARC Rating"... [Pg.437]

EFFECTS OF OVEREXPOSURE HD is a vesicant (causing blisters) and alkylating agent producing cytotoxic action on the hematopoietic (blood-forming) tissues which are especially sensitive. The rate of detoxification of HD in the body is very slow and repeated exposures produce a cumulative effect. HD has been found to be a human carcinogen by the International Agency for Research on Cancer (IARC). [Pg.429]

It is not known if phenol causes cancer in humans. However, cancer has been shown to occur in mice when phenol was applied to the skin several times each week during the whole lifetime of the animal. When it is applied in combination with certain cancer-causing chemicals, a higher rate of cancer occurs than when the carcinogens are applied alone. Phenol did not cause cancer in mice or rats when they drank water containing phenol for 2 years. The International Agency for Research on Cancer (IARC) considers phenol not classifiable as to its carcinogenicity in humans. [Pg.26]

Klein RG, Schmezer P. 1984. Quantitative measurement of the exhalation rate of volatile N-nitrosamines in inhalation experiments with anesthetized Sprague-Dawley rats. IARC Sci Publ 57 513-517. [Pg.113]


See other pages where IARC rating is mentioned: [Pg.455]    [Pg.833]    [Pg.171]    [Pg.172]    [Pg.199]    [Pg.210]    [Pg.833]    [Pg.220]    [Pg.132]    [Pg.359]    [Pg.418]    [Pg.118]    [Pg.147]    [Pg.160]    [Pg.355]    [Pg.249]    [Pg.133]    [Pg.131]   
See also in sourсe #XX -- [ Pg.50 ]




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