2- Hydroxymethyl-2-methyl-l,3-propanediol

Reaction of dihalo- and trihaloacetic acid and a,a-dihalopropionic acid with trimethylolethane (2-hydroxymethyl-2-methyl-l,3-propanediol) to give bicyclic ortho esters [204]. 

Hydroxymethyl-2-methyl-l,3-propanediol see l,l,l-tris(hydroxymethyl)ethane. 

Metriol (Pentaglycerol, 2-(Hydroxymethyl)-2-methyl-l, 3-propanediol, Methyltrimethylol-methane). H3G.C(CH20H)3 mw 120.15 white needles from abs ale mp 199° (sublimes without decompn). Was first prepd by Hosaeus (Ref 2) by condensing formaldehyde and propionic aldehyde in cold aq soln in the presence of lime. Metriol is v sol in w, ale and acet ac is insol in eth. It may be nitrated to an expl trinitrate, and acetylated to a nonexpl triacetate Refs 1) Beil 1, 520 2) H. Hosaeus, Ann... 

Polymers. AH nitro alcohols are sources of formaldehyde for cross-linking in polymers of urea, melamine, phenols, resorcinol, etc (see Amino RESINS AND PLASTICS). Nitrodiols and 2-hydroxymethyl-2-nitro-l,3-propanediol can be used as polyols to form polyester or polyurethane products (see Polyesters Urethane polymers). 2-Methyl-2-nitro-l-propanol is used in tires to promote the adhesion of mbber to tire cord (qv). Nitro alcohols are used as hardening agents in photographic processes, and 2-hydroxymethyl-2-nitro-l,3-propanediol is a cross-linking agent for starch adhesives, polyamides, urea resins, or wool, and in tanning operations (17—25). Wrinkle-resistant fabric with reduced free formaldehyde content is obtained by treatment with... 

One of the earhest extensions of the list of possible buffers for biological work was Gomori s (1946) proposal of 2,4,6-trimethylpyridine, tris(hydroxymethyl)aminomethane and 2-amino-2-methyl-l, 3-propanediol. The use of peptides such as glycylglycine and, more particularly, N-dimethyl-leucylglycine (Leonis, 1948) as biological buffers is now of little more than historical interest because a much wider range of suitable, readily water-soluble buffer substances having soluble calcium salts has been developed. 

Chemical Name Prosta-5,13-dien-l-oic acid, 9,ll,15-trihydroxy-15-methyl-, (5Z,9a,lla,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-l,3-propanediol (1 1)... 

ETHYL-2-(HYDROXYMETHYL)-l,3-PROPANEDIOL TRIACETOACETATE see ELJ600 ETHYL-p-HYDROXYPHENYL KETONE see ELL500 ETHYL (4-(m-HYDROXYPHENYL)-l-METHYL)-4-PIPERIDYL KETONE see KFKOOO... 

Figure 6. Rate of heat evolution during argon-ion laser-photoinitiated polymerization of 1-methyl-2-pyrrolidinone (MP), 9 ML of 2-ethyl-2-(hydroxymethyl)-l,3-propanediol triacrylate (TMPTA), and the dyes at a concentration of 10 m. Initiators 1) 19, 2) 18, 3) 10, 4) 16, 5) RBAX (rose bengal derivative prepared from rose bengal, which is first decarboxylated and then acetylated [36]),...

Similar solubility behavior of polyhydroxy compounds was shown in fused acetates by Burton and Crowell. Burton observed that solubility of several organic compounds at 200°C, in (Li, Na, K) acetate eutectic (mp 180°C) increases with the number of hydroxyl groups and with acidity. In weight percent the following approximate solubilities were determined methanol, 0.05% 2,4-dinitroaniline and 4-nitroaniline, < 0.5% hydroquinone and resorcinol, 1% 2-amino-2-hydroxymethyl-l, 3-propanediol and 2-amino-2-methyl-l,3-propanediol, I0% trimethylolethane and pentaerythritol were miscible in all proportions above their melting points. 

Formylation of amines and alcohols. Behai,8 discoverer of the reagent, found that it reacts unidirectionally with simple alcohols to produce alkyl formates free from acetates. Hurd et al. J found that acetic-formic anhydride (prepared from formic acid and ketene) reacts quantitatively with aniline to give formanilide. Another study10 established that acetic-formic anhydride mixes endothermally with 2-nitro-2-methyl-l-propanol, exothermally with 2-nitro-2-methyl-l,3-propanediol, and displays no appreciable temperature effect with either 2-nitro-l-butanol or tris-(hydroxymethyl)-nitromethane. Formic esters are favored by avoiding a high reaction temperature and by not using sulfuric acid as catalyst. The mixed anhydride has been used for the preparation of formyl fluoride.11... 

Fig. 1. Polyhydric alcohols. Systematic names are (1) 2,2-bis(hydroxymethyl)-l,3-propanediol (2) 2,2-[oxybis(methylene)]-bis[2-hydroxymethyl]-l,3-propanediol (3) 2,2-bis [3-hydroxy-2,2-bis(hydroxymethyl)propoxy]methyl -1,3-propanediol (4) 2-hydroxy-methyl-2-methyl-1-2-methyl-1,3-propanediol (5) 2-ethyl-2-hydroxymethyl-l,3-propanediol and (6)...

The most important members of this group from a commercial standpoint are monoethonolamine, diethanolamine, and triethanolamine. Also ovailoble in commercial quantities are the aminohydroxy derivatives of nltroparoffins, which are 2-amino-1-butanol, 2-amlno-2-methyl-1-propanol, 2-amlno-2-methyl-1,3-propanediol, 2-amino-2-ethyl-l,3-propanedial, and trls(hydroxymethyl)aminomethane. 

Pentaerythrityl tetraacetate CAS 597-71-7 EINECS/ELINCS 209-907-8 Synonyms Acetic acid, tetraester with 2,2-bis (hydroxymethyl)-l, 3-propanediol 2,2-Bis ((acetyloxy) methyl)-1,3-propanediol diacetate Normosterol Pentaer hritol tetraacetate 1,3-Propanediol, 2,2-bis (acetyloxy) methyl)-, diacetate... 

The nitro alcohols in Table 1 are manufactured in commercial quantities however, three of the five of them are used only for the production of the corresponding amino alcohols. 2-Methyl-2-nitro-l-propanol (NMP) is available as the crystalline soHd or as a mixture with siHcon dioxide. 2-Hydroxymethyl-2-nitro-1,3-propanediol is available as the soHd ( 9.15/kg), a 50% solution in water ( 2.33/kg), a 25% solution in water ( 1.41/kg), or as... 

Amino-2-metbyl-1 -propanediol 2-Ammo-2-meibyl-l, -dihydroxy-propane or Bis(hydroxymethyl )metbyl-aminometbane called in Beil /3-Amino-j8-methyl-trimethylenglykol), HO-CH,—C(NH )-CH. OH ... 

A. Hexahydro-3-(hydroxymethyl)-8a-methyl-2-phenyl[2S,3S,8aR]-5-oxo-5H-oxazolo(3,2-a]pyndine (Bicyclic lactam). To a warm solution of (1 S,2S)-(+)-2-amino-l-phenyl-1,3-propanediol (32.4 g, 194 mmol) (Note 1) in toluene (800 mL), 5-oxo-... 

Dinitropbenylamine)-trimethylolme thane N-(2,4-Dinitrophenyl)-( tris-hydroxy-methyl-methyl)-amine 2-(2, 4 -Dinitroanilino)-2-hydroxymethyl-l,3-propanediol 2,4-Di-nitrophenyltrimethylolmethylamine or 2,4-D initropheny Itri hydroxymet hylmethylamine,... 

SYNS ACETOACETIC ACID, TRIESTER WTTH 2-ETH T 2-(HYDROXYMETHYL)-l, 3-PROPANEDIOL ACETOACETIC ACID, 1,1,1-TRIHYDROXY-METHYL-PROPANE TRIESTER BUTANOIC ACID, 3-OXO-, 2-((l,3-DIOXOBUTOXY)METHYL)-2-ETHYL-l,3-PROPANE-DIYL ESTER 1,3-PROPANEDIOL, 2-ETHYL-2-(HYDROXYMETHYL)-, TRL3CETOACETATE TRIMETmEOLPROPANE TRIACETOACETATE... 

HeprOllicate. 3 -Pyrtd i n eca rbo.tylic acid 2-hexyl-2.((<3.pyridinylcarbonyl>oxy]methyl]-l,3-propanediyl ester nicotinic acid triester wilh 2-hexyl-2-(hydroxy,nethyl)-1.3-propanediot 2-hexyl-2-(hydroxymethyl)- [.3-propanediol trinicotinate 2.2-dihydroxymethyl -n-octano trinicotinate 1,1,1-trimethylolheptane trinicotinate 1,1,1 -(trihydroxy. methyi)heptane trinicotinate Meg rin. mol wt... 

Hydroxy-2-(3-hydroxy-3-methylbutyl)-5-methoxybibenzyl, in H-20173 11 -Hydroxy-3-( 1 -hydroxy-3-methylbutyl)-4-methoxy-9-methyl-5//,7//-dibenzo[/ ,g][l,5] dioxocin-5-one, see P-10025 1 -[4-[2-Hydroxy-1 -(hydroxymethyl)ethoxy]-3-methoxyphenyl]-2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]- ,3-propanediol, H-30157 9-Hydroxy-3-(hydroxymethyl)furo[3,2-/ ] naphtho[2,3- furan-5,10-dione, in H-30185... 

An ethereal soln. of 2-(l-ethyl)propyl-4-methyl-4-hydroxymethyl-2-oxazoline added slowly to LiAlH4 in ether, and refluxed 20 hrs. 2-(2-ethyl) butylamino-2-methyl-l,3-propanediol. Y 92%. F. e. s. D. Misiti, A. Amato, and V. Rosnati, G. 93, 1118 (1963). 

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