High electrospray ionization mass

Electrospray ionization mass spectrometry (ESI-MS) is an analytical method for mass determination of ionized molecules. It is a commonly used method for soft ionization of peptides and proteins in quadmpole, ion-trap, or time-of-flight mass spectrometers. The ionization is performed by application of a high voltage to a stream of liquid emitted from a capillaty. The highly charged droplets are shrunk and the resulting peptide or protein ions are sampled and separated by the mass spectrometer. [Pg.458]

Paganga, G. et al.. The polyphenolic content of fruit and vegetables and their antioxidant activities what does a serving constitute Free Radical Res., 30, 153, 1999. Maatta, K.R. et al.. High-performance liquid chromatography (HPLC) analysis of phenolic compounds in berries with diode array and electrospray ionization mass spectrometric (MS) detection Rihes species, J. Agric. Food Chem., 51, 6736, 2003. [Pg.84]

Stintzing, F.C., Schieber, A., and Carle, R., Identification of betalains from yellow beet (Beta vulgaris L.) and cactus pear (Opuntia ficus-indica (L.) Mill.) by high-performance liquid chromatography-electrospray ionization mass spectrometry, J. Agric. Food Chem., 50, 2302, 2002. [Pg.95]

On the other hand, electrospray ionization mass spectrometry (ESMS) has been first combined with electrochemistry at ITIES in order to confirm the stoichiometry of a complex ion transferred into an organic phase directly. ESMS is now becoming a popular and powerful technique not only in chemistry but also in biology, pharmacy, medical science, etc. Electrospray (ES) ionization is exceedingly effective resource for producing gas-phase ions from various solutions which contain any kinds of ion. Thus, ESMS can sometimes give us highly useful information in comparison with electrochemical results. [Pg.630]

Liu, C. L. and Verma, S. S., Direct coupling of ionic high performance liquid chromatography with electrospray ionization mass spectrometry utilizing a microdialysis junction interface, ]. Chromatogr. A, 835, 93, 1999. [Pg.310]

Yiang, Y. Hofstadler, S. A. A highly efficient and automated method of purifying and desalting PCR products by electrospray ionization mass spectrometry. Anal. Biochem. 2003,316, 50-57. [Pg.35]

HIGH-THROUGHPUT MICROBIAL CHARACTERIZATIONS USING ELECTROSPRAY IONIZATION MASS SPECTROMETRY AND ITS ROLE IN FUNCTIONAL GENOMICS... [Pg.229]

Vaidyanathan, S. Kell, D. B. Goodacre, R. Flow-injection electrospray ionization mass spectrometry of crude cell extracts for high-throughput bacterial identification. J. Am. Soc. Mass Spectrom. 2002,13,118-128. [Pg.251]

Premstaller, A., Oberacher, H., Walcher, W., Timperio, A.M., Zolla, L., Chervet, J.P., Cavusoglu, N., van Dorsselaer, A., Huber, C.G. (2001). High-performance liquid chromatography-electrospray ionization mass spectrometry using monolithic capillary columns for proteomic studies. Anal. Chem. 73, 2390-2396. [Pg.175]

Racaityte, K., Lutz, E.S.M., Unger, K.K., Lubda, D., Boos, K.S. (2000). Analysis of neuropeptide Y and its metabolites by high-performance liquid chromatography—electrospray ionization mass spectrometry and integrated sample cleanup with a novel restricted-access sulphonic acid cation exchanger. J. Chromatogr. A 890, 135-144. [Pg.219]

Huber, C.G., Premstaller, A. (1999). Evaluation of volatile eluents and electrolytes for high-performance liquid chromatography-electrospray ionization mass spectrometry and capillary electrophoresis-electrospray ionization mass spectrometry of proteins. I. Liquid chromatography. J. Chromatogr. A 849, 161-173. [Pg.316]

Zhang and Nunes [92] studied the structure and the generation mechanism of a novel degradation product formed by oxidatively induced coupling of miconazole nitrate with butylated hydroxy toluene in a topical ointment studied by high performance liquid chromatography-electrospray ionization mass spectrometry and organic synthesis. [Pg.57]

M. Puchalska, K. Polec Pawlak, I. Zadrozna, H. Hryszko and M. Jarosz, Identification of indigoid dyes in natural organic pigments used in historical art objects by high performance liquid chromatography coupled to electrospray ionization mass spectrometry, J. Mass Spectrom., 39, 1441 1449 (2004). [Pg.387]

M. J. Dubber, V. Sewram, N. Mshicileli, G.S. Shephard and I. Kanfer, The simultaneous determination of selected flavonol glycosides and aglycones in Ginkgo biloba oral dosage forms by high performance liquid chromatography electrospray ionization mass spectrometry, J. Pharmaceut. Biomed., 37, 723 731 (2005). [Pg.388]

Berardini N, Carle R and Schieber A. 2004. Characterization of gallotannins and benzophenone derivatives from mango (Mangifera indica L. cv. Tommy Atkins ) peels, pulp and kernels by high-performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom 18(19) 2208—2216. [Pg.80]

BARNES, K.A., SMITH, R.A., WILLIAMS, K., DAMANT, A.P., SHEPHERD, MJ.A., Microbore high performance liquid chromatography/electrospray ionization mass spectrometry method for the determination of the phytoestrogens genistein and daidzein in comminuted baby foods and soya flour, Rapid Comm. Mass Spectrom., 1998,12,130-138. [Pg.195]

S. Hakkinen and S. Auriola, High-performance liquid chromatography with electrospray ionization mass spectrometry and diode array ultraviolet detection in the identification of flavonol aglycones and glycosides in berries. J. Chromatogr.A 829 (1998) 91-100. [Pg.357]

High-performance liquid chromatography was combined with electrospray ionization mass spectrometry (i.e., HPLC-ESI-MS) to differentiate quantitatively crude natural extracts of various environmental samples [711, 712] and with NMR (i.e., HPLC-MS-NMR) for quantitation measurement [713]. [Pg.88]

Ling V., Guzzetta A.W., Canova-Davis E., Stults J.T., Hancock W.S., Covey T.R., and Shushan B.I. (1991), Characterization of the tryptic map of recombinant DNA derived tissue plasminogen activator by high-performance liquid chromatography-electrospray ionization mass spectrometry, Anal. Chem. 63, 2909-2915. [Pg.270]

High-resolution electrospray ionization mass spectrometry (HR-ESI-MS) calculated for C,Hin04NaS [M+Na]+ 189.0198 found 189.0192. [Pg.221]

Breindahl T, Andreasen K. 1999. Determination of 11-nor-delta9-tetrahydrocannabinol-9-carboxylic acid in urine using high-performance liquid chromatography and electrospray ionization mass spectrometry. J Chromatogr B Biomed Sci Appl 732 155. [Pg.169]

Li KY, Cheng ZN, Li X, Bai XL, Zhang BK, et al. 2004b. Simultaneous determination of quetiapine and three metabolites in human plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry. Acta Pharmacol Sin 25 110. [Pg.172]

Numerous workers have demonstrated the applicability of electrospray ionization mass spectrometry (ESI/MS) for the detection and analysis of biomolecules with highly electronegative groups (reviewed by Wood et al., 2003, and for neutral steroids by Higashi and Shimada, 2004). The sensitivity of detection of neurosteroids can also be enhanced by derivatization when they are analyzed by nano-electrospray/mass spectrometry procedures. Neurosteroid sulfates can be easily prepared in a single-step reaction in pyridine with the N,N-dimethylformamide complex of sulfur trioxide (Chatman et al., 1999). Another elegant... [Pg.180]