Flavonol aglycones

FlESCHi M, CODIGNOLA A and Luppi MOSCA A M (1989) Mutagenic flavonol aglycones in infusions and in fresh and pickled vegetables , JFood Sci, 42, 1492-5. 

S. Hakkinen and S. Auriola, High performance liquid chromatography with electrospray ioniza tion mass spectrometry and diode array ultraviolet detection in the identification of flavonol aglycones and glycosides in berries, J. Chromatogr. A, 829, 91 100 (1998). 

It was stated that this combined technique (HPLC-DAD, HPLC-ESI-MS, GC-MS) allows the safe identification of flavonol aglycones and glycosides and can be used for the analysis of these compounds in berries [161]. 

After hydrolysis of the obtained flavonol glycosides, flavonol aglycones and sugars were identified by HPLC and gas chromatography-mass spectrometry (GC-MS), respectively. (109 words)... 

Ma, Y.L. et ak. Characterization of flavone and flavonol aglycones by collision-induced dissociation tandem mass spectrometry, Rapid Commun. Mass Spectrom., 11, 1357, 1997. 

Both human and animal pharmacokinetic studies have been done on ginkgo flavonol aglycones (quercetin, kaempferol, and isorhamnetin) and terpene trilactones (ginkgolide A and B and bilobalide). 

Figure 8.1 Structures of main flavonol aglycones and quercetin glycosides present in plant foods.

Estrella, I., Alonso, E., and Revilla, E. (1987). Presence of flavonol aglycones in Sherry wines and changes in their content during aging. Z. Lebensm. Unters. Forsch. 184, 27-29. 

The addition of micelles that migrate counter-current in the capillary can be used for the separation of apolar compounds, particularly when organic solvents such as methanol are added to the buffer solution. Using this method, flavone and flavonol aglycones present in honey were separated, although no specific advantage with HPLC separation using reversed-phase columns was observed. 

Markham, K.R. Temai, B. 1976. 13C NMR of flavonoids-II Flavonoids other then flavone and flavonol aglycones. Tetrahedron 32 2607-2612. 

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