Hemophilus influenzae vaccine

Because patient with SCD have impaired splenic function, they are less adequately protected against encapsulated organisms such as S. pneumoniae, Hemophilus influenzae, and Salmonella. The use of pneumococcal vaccine in SCD patients has decreased the rates of morbidity and mortality dramatically. However, there are still groups of SCD children who continue to have high rates of invasive pneumococcal infections.17 Two pneumococcal vaccines are available. The 7-valent conjugate... 

Kantor E, Luxenberg JS, Lncas AH, Granoff DM. Phase 1 stndy of the immnnogenicity and safety of conjngated Hemophilus influenzae type b vaccines in the elderly. Vaccine 1997 15(2) 129-32. 

Hemophilus influenzae type b (conjugate) A. Events described in the manufacturers package insert as contraindications to additional doses of the vaccine See package insert... 

In the USA, the National Childhood Vaccine Injury Act of 1986 established the National Vaccine Injury Compensation Program as a federal no-fault compensation system for individuals who may have been injured by specific vaccines. This compensation program relies on a Vaccine Injury Table that lists the vaccines that are covered by the program, as well as injuries, disabilities, illnesses, and conditions (including death) for which compensation may be awarded. To better reflect current scientific knowledge about vaccine injuries, the Vaccine Injury Table was revised in 1995 and has been subsequently further modified. The latest modification, which became effective on December 1, 2004, is shown in Table 7. This revision took into account a review of the literature on specific adverse consequences of pertussis and rubella vaccines performed and published by the lOM (SED-12, 817) (SED-12, 825). In addition to the seven vaccines (diphtheria, pertussis, tetanus, measles, mumps, rubella, and poliomyelitis) included in the first Vaccine Injury Table, the 1997 revision includes hepatitis B, Hemophilus influenzae type b, and Varicella vaccines, as well as any future licensed vaccine recommended by the Advisory Committee on Immunization Practices (ACIP) for routine administration to children (38). 

IX. Hemophilus influenzae type b polysaccharide conjugate vaccines No condition specified for compensation Not applicable... 

Evidence DT/Td/tetanus toxoid Measles vaccine Mumps vaccine OPV/IPV Hepatitis B vaccine Hemophilus influenzae type b (Hib) vaccine... 

Clinically important, potentially hazardous interactions with amiloride, aminoglycosides, amphotericin B, ampicillin, anisindione, anticoagulants, armodafinil, atorvastatin, azathioprine, azithromycin, bacampicillin, basiliximab, bezafibrate, bosentan, bupropion, carbenicillin, caspofungin, cholestyramine, clarithromycin, cloxacillin, co-trimoxazole, corticosteroids, cyclophosphamide, daclizumab, danazol, dicloxacillin, dicumarol, digoxin, diltiazem, disulfiram, echinacea, erythromycin, ethotoin, etoposide, ezetimibe, flunisolide, fluoxymesterone, fluvastatin, foscarnet, fosphenytoin, gemfibrozil, hemophilus B vaccine, HMG-CoA reductase inhibitors, imatinib, imipenem/cilastatin, influenza vaccines, ketoconazole, lanreotide, lopinavir, lovastatin, mephenytoin, methicillin, methoxsalen, methylphenidate, methylprednisolone, methyltestosterone, mezlocillin, mizolastine, mycophenolate, nafcillin, nisoldipine, NSAIDs, orlistat, oxacillin, penicillins, phellodendron, phenytoin, pravastatin, prednisolone, prednisone, pristinamycin, ranolazine, red rice yeast, rifabutin, rifampin, rifapentine, ritonavir, rosuvastatin, simvastatin, sirolimus, spironolactone, St John s wort, sulfacetamide, sulfadiazine, sulfamethoxazole, sulfisoxazole, sulfonamides, tacrolimus, telithromycin, tenoxicam, testosterone, ticarcillin, tolvaptan, trabectedin, triamterene, troleandomycin, ursodeoxycholic acid, vaccines, vecuronium, warfarin, zofenopril... 

The three most likely pathogens of bacterial meningitis in the United States are Streptococcus pneumoniae, Neisseria meningitidis, and Hemophilus influenzae, although routine vaccination may cause a change in the epidemiology in the years to come. 

Certain vaccines manufactured hy various companies are considered interchangeable. Hepatitis A and hepatitis B vaccines are considered interchangeable. It is preferable to use diphtheria-tetanus-acellular pertussis (DTaP) vaccine from the same manufacturer to complete the entire primary series. However, immunization should not be delayed if the particular type of vaccine administered for the initial doses cannot be ascertained easily. Finally, all licensed Hemophilus influenzae type b conjugate vaccines are considered interchangeable for the primary series of three doses of vaccine. ... 

Hib Hemophilus influenzae type b HSCT hematopoietic stem cell transplant IMIG intramuscular immunoglobulin IPV inactivated polio vaccine ITP immune thrombocytopenic purpura IVIG intravenous immunoglobulin LAIV live attenuated influenza vaccine MMR measles-mumps-rubeUa vaccine OPV oral polio vaccine... 

Comvax (combination vaccine, containing rHBsAg produced in S. cerevisiae as one component) Merck vaccination of infants against hemophilus influenzae type B and hepatitis B 1996 (US)... 

A polysaccharide vaccine made from Hemophilus influenza gives a poor response in very young children, where the disease threat is maximum. The vaccine is also poor in young monkeys. The data that is presented in Table 5 are normalized values obtained by radioimmunoassays carried out by Dr. Porter Anderson. The value of 100 was assigned, in each case, to the amount of radioactivity found prior to immunization. The vaccine alone caused a small boost in antibody production, but when given with polydCLC) there was a more pronounced boost (H. B. Levy, E. Stephen, and D. Harrington, unpublished observations). Poly(A) poly(U) complexed to CMC and poly (L-lysine) was not as effective as poly(ICLC). 

Table 5. Effect of low doses of poly(ICLC) on antibody production by rhesus monkeys in response to a polysaccharide vaccine for Hemophilus influenza. 

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