Tissues haemopoietic

Tissue expression Mainly white and brown adipose tissue weak expression in liver, muscle, gut, macrophages, pancreatic (3-cells and haemopoietic tissues... 

Aplastic anaemia is due to loss of haemopoietic tissue in bone marrow and therefore decreased production of red blood cells. 

These modulations suggest that Chlorella vulgaris potentiates chemopreventive action via the perinatal passage of active constituents and/or metabolites. Moreover, Chlorella vulgaris is capable of protecting haemopoietic tissue of whole body-irradiated mice [9]. This protection is seen both in terms of haemopoietic stem cells and the survival of animals. 

Folate is needed for cells undergoing rapid division and growth, e.g. haemopoietic tissue in bone marrow. Deficiency causes megaloblastic anaemia. 

Lord, B. I. and Marsh, J. C. W. (1993) Enrichment of progenitor cell populations from murine and human haemopoietic tissue, in Haemopoeisis A Practical Approach (Testa, N. G. and Molineux, G., eds.), Oxford University Press, Oxford, UK, pp. 21-36. 

In the animal body, of course most of the cells stick to one another to form solid tissues and organs. The cells of one particular tissue, blood, are derived from stem cells in the haemopoietic tissue but are non-adhesive for the majority of their short, mature lives. Thus, blood was an early subject for calorimetric study, largely by some of the clinical scientists in Lund, the city that is the spiritual home of the LKB/Thermometric calorimeters. In the early days when batch vessels had no stirrers and were only rotated, the cells were pumped through a flow calorimeter because sedimentation in batch vessels caused the crowding effect (see Section 3.2.1) due to the onset of anoxic conditions. 

The various cell types are distributed differently within various types of connective tissue fibroblasts often found lying close to collagen fibres, whilst macrophages and mast cells usually appear in clusters around blood vessels. Additionally, whereas fibroblasts are widespread, macrophages are absent from some types of connective tissue, tendons for example. Specialized cells also occur within particular locations for example osteoblasts and osteoclasts (bone), chondrocytes (cartilage), adipocytes (fat tissue) and haemopoietic cells (bone marrow). 

B15. Beschomer, R., Horny, H. P., Petruch, U. R., and Kaiserling, E., Frequent expression of haemopoietic and non-haemopoietic antigens by reactive plasma cells An immunohistochemical study using formalin-fixed, paraffin-embedded tissue. Histol. Histopathol. 14, 805-812 (1999). 

Fibroblasts, along with cells from adipose tissue, cardiac and skeletal muscle and the vascular endothelium, are derived from the mesenchyme while epithelial cells are obtained from the cervix, kidney tubes, bronchii, trachea etc. Neurones and glial cells are of neuroectodermal origin and blood cells arise from the haemopoietic system. 

The presence of 5-methylcytosine in DNA of plants and animals was reported in 1951 [259, 260]. It was identified in five out of eighteen preparations from human haemopoietic and other tissues [261]. 5-Methylcytosine was found to occur in both serine-specific r-RNAs from brewer s yeast [262] and a yeast tyrosine r-RNA [263], but not in alanine -RNA from yeast [264]. 

Inorganic phosphates are accumulated specifically by the trabecular bone-tissue which lies close to the haemopoietic red bone-marrow. The overproduction of red cells in polycythaemia is treated clinically with (half-life 14... 

Cox MA, Kastrup J, Hrubisko M. Historical perspectives and the future of adverse reactions associated with haemopoietic stem cells cryopreserved with dimethyl sulfoxide. Cell Tissue Bank 2012 13(2) 203-15. 

Before a tissue can be analysed, it must be completely separated from neighbouring tissues which would otherwise contaminate it and invalidate the results. This is difficult with calcified tissues since they are hard and cannot be cut or broken readily without generation of heat which may cause decomposition moreover, they are frequently in close juxtaposition to other tissues. Thus in addition to bone tissue the bones contain cartilage, periosteum (an uncalcified connective tissue), and fatty or haemopoietic marrow. Compact (cortical) bone is easily isolated in a relatively pure state from a long bone, such as a femur, of a large animal like the cow. 

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