Glutaminic acid

Histamine is synthesised by decarboxylation of histidine, its amino-acid precursor, by the specific enzyme histidine decarboxylase, which like glutaminic acid decarboxylase requires pyridoxal phosphate as co-factor. Histidine is a poor substrate for the L-amino-acid decarboxylase responsible for DA and NA synthesis. The synthesis of histamine in the brain can be increased by the administration of histidine, so its decarboxylase is presumably not saturated normally, but it can be inhibited by a fluoromethylhistidine. No high-affinity neuronal uptake has been demonstrated for histamine although after initial metabolism by histamine A-methyl transferase to 3-methylhistamine, it is deaminated by intraneuronal MAOb to 3-methylimidazole acetic acid (Fig. 13.4). A Ca +-dependent KCl-induced release of histamine has been demonstrated by microdialysis in the rat hypothalamus (Russell et al. 1990) but its overflow in some areas, such as the striatum, is neither increased by KCl nor reduced by tetradotoxin and probably comes from mast cells. 

Methotrexate Methotrexate, N- p-[[2,4-diamino-6-piperidinyl)methyl]methylamino]-benzoyl]-L-( )-glutamic acid (30.1.1.8), is made by reacting A-(4-methylaminoben-zoyl)glutaminic acid (30.1.1.3) with 2-amino-4-hydroxyl-6-bromomethylpteridine... 

Vinblastine suppresses cell growth during metaphase, affects amino acid metabolism, in particular at the level of including glutamine acid into the citric acid cycle and preventing it from transformation into urea, and it also inhibits protein and nucleic acid synthesis. 

HOPE HEPES-glutaminic acid buffer-mediated organic solvent protein effect... 

Glutamine, Glutaminic Acid, HOOC—CH2—CH2—CH(NH2)—COOH, a-Amino... 

The next higher di-basic acid to succinic acid, viz., glutaric acid, yields an amino acid known as glutamine, glutaminic acid, or glutamic acid. It occurs more widely distributed than any of the other amino acids. Most proteins yield larger amounts of it than of any other... 

Garlic Tablets Cores (100 mg) Glibenclamide Tablets (5 mg) Glutaminic Acid Tablets (550 mg) Gramicidin Ophthalmic Solution... 

Agaratine (3.48) is another glutaminic acid derivative that is found in Agaricus bisporus, where it is present to the extent of 0.1-0.3% dry weight. This metabolite has attracted interest because it may be hydrolyzed enzymatically to... 

The active ingredients are diphosphonic acids - dicarboxypropane diphosphonic acid (DPD), hydroxymethylene diphosphonic acid (HDP or HMDP), hydroxyethylidene diphosphonic acid (EHDP), methylene diphosphonic acid (MDP) - or their sodium salts. As stabilizers are used N-(4-aminobenzoyl)-L-glutaminic acid, gentisic acid (2,5-dihydroxybenzoic acid), ascorbic acid, or carbamide. For reduction of Tc-pertechne-tate to lower oxidation states, tin(II) chloride and tin(II) fluoride are employed. 

Glutathione is the tripeptide built up from glutaminic acid, cysteine, and glycine. 

HYDROCHLORIDE a-GLUTAMIC ACID HYDROCHLORIDE GLUTAMNIC ACID HYDROCHLORIDE /-GLUTAMINIC ACID HYDROCHLORIDE... 

Agaritine (L-glutaminic acid 5- A( -[4-(hydroxy-methyl)-phenyl]hydrazide)). A compound from the cultivated mushroom Agaricus bisporus and related species. ... 

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