L -Glutaminic acid

The active ingredients are diphosphonic acids - dicarboxypropane diphosphonic acid (DPD), hydroxymethylene diphosphonic acid (HDP or HMDP), hydroxyethylidene diphosphonic acid (EHDP), methylene diphosphonic acid (MDP) - or their sodium salts. As stabilizers are used N-(4-aminobenzoyl)-L-glutaminic acid, gentisic acid (2,5-dihydroxybenzoic acid), ascorbic acid, or carbamide. For reduction of Tc-pertechne-tate to lower oxidation states, tin(II) chloride and tin(II) fluoride are employed. 

Agaritine (L-glutaminic acid 5- A( -[4-(hydroxy-methyl)-phenyl]hydrazide)). A compound from the cultivated mushroom Agaricus bisporus and related species. ... 

Glutaminic acid l-Glutaminic acid Glutaminol Glutaton... 

L-Glutamine, N2-(3-aminopropyl)-N2-dodecyl-. See Ami nopropyl laurylglutamine Glutaminic acid l-Glutaminic acid Glutaminol. See L-Glutamic acid... 

Both threo- (14) and eo f >"4-fluoro-DL-glutamic acid (/5) are noncompetitive inhibitors of glutamine synthase, an enzyme that catalyzes the synthesis of glutamine from L-glutamic acid and ammonia. This mhibibon may explain the... 

It is a peptide containing 27 amino acid residues containing the amino acids L-histidine (His) L-aspartic acid (Asp) L-serine (Ser) glycine (Gly) L-threonine (Thr) L-phenyl-alanine (Phe) L-glutamic acid (Glu) L-glutamine [Glu(NHj)] L-leucine (Leu) L-arginine (Arg) L-alanine (Ala) and L-valinamide (Va -NHj). 

Histamine is synthesised by decarboxylation of histidine, its amino-acid precursor, by the specific enzyme histidine decarboxylase, which like glutaminic acid decarboxylase requires pyridoxal phosphate as co-factor. Histidine is a poor substrate for the L-amino-acid decarboxylase responsible for DA and NA synthesis. The synthesis of histamine in the brain can be increased by the administration of histidine, so its decarboxylase is presumably not saturated normally, but it can be inhibited by a fluoromethylhistidine. No high-affinity neuronal uptake has been demonstrated for histamine although after initial metabolism by histamine A-methyl transferase to 3-methylhistamine, it is deaminated by intraneuronal MAOb to 3-methylimidazole acetic acid (Fig. 13.4). A Ca +-dependent KCl-induced release of histamine has been demonstrated by microdialysis in the rat hypothalamus (Russell et al. 1990) but its overflow in some areas, such as the striatum, is neither increased by KCl nor reduced by tetradotoxin and probably comes from mast cells. 

Such enzymes catalyse the condensation of specific compounds, accompanied by the breakdown of a pyrophosphate bond in adenosine triphosphate (10.64). Adenosine is the condensation product of a pentose (D-ribofuranose) and a purine (adenine). Scheme 10.15 shows the action of glutamine synthetase on a mixture of L-glutamic acid (10.65) and... 

Methotrexate Methotrexate, N- p-[[2,4-diamino-6-piperidinyl)methyl]methylamino]-benzoyl]-L-( )-glutamic acid (30.1.1.8), is made by reacting A-(4-methylaminoben-zoyl)glutaminic acid (30.1.1.3) with 2-amino-4-hydroxyl-6-bromomethylpteridine... 

L-aspartic acid L-cysteine L-glutamine L-glutamic acid L-glycine L-histidine Histidine-derived alkaloids True alkaloids... 

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