Glucose study

Perley M, Kpnis D (1967) Plasma insulin responses to oral and intravenous glucose studies in normal and diabetic subjects. J Clin Invest 46 1954—1962... 

Glucose Studied with 14C Labeled Glucose. J. Amer. chem. Soc. 72, 3964 (1950). 

A number of nonenzymatic glucose study have been reported by amperometricaUy measuring the current response of direct glucose oxidation [33, 34]. The electrocatalytic activity of the electrode material is the key factor affecting the sensitivity and selectivity of glucose detection for nonenzymatic glucose sensors. 

Haworth formulas are satisfactory for representing configurational relationships in pyranose forms but are uninformative as to carbohydrate conformations X ray crystal lographic studies of a large number of carbohydrates reveal that the six membered pyra nose ring of D glucose adopts a chair conformation... 

The classical approach to structure determination in carbohydrate chemistry is best exemplified by Fischer s work with D glucose A detailed account of this study appears in the August 1941 issue of the Journal of Chemical Education (pp 353-357)... 

Biochemistry resulted from the early elucidation of the pathway of enzymatic conversion of glucose to ethanol by yeasts and its relation to carbohydrate metaboHsm in animals. The word enzyme means "in yeast," and the earfler word ferment has an obvious connection. Partly because of the importance of wine and related products and partly because yeasts are relatively easily studied, yeasts and fermentation were important in early scientific development and stiU figure widely in studies of biochemical mechanisms, genetic control, cell characteristics, etc. Fermentation yeast was the first eukaryote to have its genome elucidated. 

A compound which is a good choice for an artificial electron relay is one which can reach the reduced FADH2 active site, undergo fast electron transfer, and then transport the electrons to the electrodes as rapidly as possible. Electron-transport rate studies have been done for an enzyme electrode for glucose (G) using interdigitated array electrodes (41). The following mechanism for redox reactions in osmium polymer—GOD biosensor films has... 

Aminoglycoside Biosynthesis. The biosynthesis of the aminoglycosides has been extensively studied and reviewed (117—119). Perhaps the most interesting aspect is the biosynthesis of 2-deoxystreptamiae (1, R = H), in which the C-1 and C-6 of a D-glucose molecule become the C-1 and C-2 of 2-deoxystreptamiae by way of the intermediate 2-deoxy-j //(9-iaosose. The details of this conversion are stiU unclear. 

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