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Gene expression profiles

Landgrebe J, Welzl G, Metz T et al (2002) Molecular characterisation of antidepressant effects in the mouse brain using gene expression profiling. J Psychiatr Res 36 119-129... [Pg.116]

Refers to the physical substrate to which biological samples are attached to create features (spots). In gene expression profiling arrays are hybridized with labeled sample and then scanned and analyzed to generate data. [Pg.222]

Gene Expression Analysis. Figure 2 Contribution of gene expression profiling to the drug discovery process. [Pg.529]

The most common application of microarray technology is in monitoring gene expression (gene expression profiling). [Pg.765]

Toxicology Many companies are known to use gene expression profiling to assess the potential toxicity of lead compounds. This approach may require a database of reference compounds with known pharmacological and toxicological properties. Lead compounds can be compared to the database to predict compound-related or mechanism-related toxicity [5]. [Pg.769]

Filby, A.L., Thorpe, K.L., Maack, G. et al. (2007b). Gene expression profiles revealing the mechanisms of anti-androgen and estrogen-induced feminization in fish. Aquatic... [Pg.347]

Li Y, Hong X, Hussain M, Sarkar SH, Li R, Sarkar FH. Gene expression profiling revealed novel molecular targets of docetaxel and estramustine combination treatment in prostate cancer cells. Mol Cancer Ther 2005 4 389-98. [Pg.164]

Luo W, Fan W, Xie H, ling L, Ricicki E, Vouros P, et al. Phenotypic anchoring of global gene expression profiles induced by A -hydroxy-4-acetylaminobiphenyl and benzo[a]pyrene diol epoxide reveals correlations between expression profiles and mechanism of toxicity. Chem Res Toxicol 2005 18 619-29. [Pg.165]

LEE c-K, KLOPP R G, WEINDRUCH R and PROLLA T A (1999) Gene expression profile of aging and its retardation by caloric restriction. Science 285 1390-93. [Pg.237]

Adjunctive to flux control analysis, other components of metabolism that contribute to product accumulation are needed including (1) substrate/precursor pool sizes (metabolomics), (2) co-factor capacities (metabolomics), (3) gene expression profiles (transcriptomics and quanfifafive real-time PCR), (4) protein profiles (pro-... [Pg.356]

Watanabe N, Ando K, Yoshida S, et al. Gene expression profile analysis of rheumatoid synovial fibroblast cultures revealing the overexpression of genes responsible for tumor-like growth of rheumatoid synovium. Biochem Biophys Res Commun 2002 294(5) 1121-1129. [Pg.195]

Zollanvari, A. et al. (2009) Analysis and modeling of time-course gene-expression profiles from nanomaterial-exposed primary human epidermal keratinocytes. BMC Bioinformatics, 10, (Suppl. 11) S10. [Pg.211]

Welage, L. Barnett, C. P. Landowski, D. Foster, D. Fleisher, K.-D. Lee et al. Comparison of Human Duodenum and Caco-2 Gene Expression Profiles for 12,000 Gene Sequences Tags and Correlation with Permeability of 26 Drugs., Pharm. Res. 2002, 29, 1400-1416... [Pg.84]

Sun, D., et al. Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs. Pharm. Res. 2002, 19, 1400-1416. [Pg.269]

Tanabe L et al. MedMiner an internet text-mining tool for biomedical information, with application to gene expression profiling. BioTechniques 1999 27 1210-1217. [Pg.113]

Takenaka M et al. Gene expression profiling of the collecting duct in the mouse renal inner medulla. Kidney Int 2000 57 19-24. [Pg.114]

Alizedah AA et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000 403 503-511. [Pg.114]

Bertucci F et al. Gene expression profiling of primary breast carcinomas using arrays of candidate genes. Hum Mol Genet 2000 9 2981-2991. [Pg.114]

Hedenfalk I et al. Gene expression profiles in hereditary breast cancer. N Engl J Med 2001 344 539-548. [Pg.114]

Sgroi DC et al. In vivo gene expression profile analysis of human breast cancer progression. Cancer Res 1999 59 5656-5661. [Pg.114]

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Brain gene expression profile

Breast cancer cells gene expression profiling

Caco gene expression profiling

Cell characterization by gene expression profiling

Clinical trials gene expression profiling

Cyclin-dependent kinase gene expression profiling

Drug Targets and Toxicological Profiles by Gene Expression Analysis

Expression profile

Expression profiling

Expression profiling gene)

Expression profiling gene)

Gene expression analyses/profiling

Gene expression profile libraries

Gene expression profiles polymers

Gene expression profiles value

Gene expression profiling development

Gene expression profiling methods

Gene expression profiling using microarrays

Global gene expression profiling

Model for Gene Expression Profiling

Primary tumor gene expression profile

Single nucleotide polymorphism SNPs) gene expression profiling

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