Global gene expression profiling

Luo W, Fan W, Xie H, ling L, Ricicki E, Vouros P, et al. Phenotypic anchoring of global gene expression profiles induced by A -hydroxy-4-acetylaminobiphenyl and benzo[a]pyrene diol epoxide reveals correlations between expression profiles and mechanism of toxicity. Chem Res Toxicol 2005 18 619-29. 

Smirnova, J. B., Selley, J. N., Sanchez-Cabo, F., Carroll, K., Eddy, A. A., McCarthy, J. E., Hubbard, S. J., Pavitt, G. D., Grant, C. M., and Ashe, M. P. (2005). Global gene expression profiling reveals widespread yet distinctive translational responses to different eukaryotic translation initiation factor 2B-targeting stress pathways. Mol. Cell Biol. 25, 9340-9349. 

Roberts, C.J., Nelson, B., and Marton, M.J., Signaling and circuitry of multiple MAKP pathways revealed by a matrix of global gene expression profiles. Science, 287, 873-880, 2000. 

Signaling and dreuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles. Science 287, 873-880. 

Zucchi, S., Oggier, D.M., Fent, K. Global gene expression profile induced by the UV-filter 2-ethyl-hexyl-4-trimethoxycinnamate (EHMC) in zebrafish (Danio rerio). Environ. Pollut. 159, 3086-3096 (2011)... 

Aside from their effect on lipid-lowering pathways, statins have been reported to affect most of the molecular mechanisms implicated in atherosclerosis (Fig. 3). Global gene expression profiling has been valuable towards elucidating this association. 

N.G. Sandler, M.M. Mentink-Kane, A.W. Cheever, T.A. Wynn, Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Thl and Th2 responses in tissue repair,/. Immunol. 2003, 171, 3655-3667. 

Barella, L., Muller, P.Y., Schlachter, M., Hunziker, W., Stockiin, E., Spitzer, V., Meier, N., de Pascual-Teresa, S., Minihane, A. M., and Rimbach, G., Identification of hepatic molecular mechanisms of action of alpha-tocopherol using global gene expression profile analysis in rats, Biochim. Biophys. Acta 1689 (1), 66-74, 2004. 

Jiang, Y., Gerhold, D., Holder, D., et al. 2007. Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles. J. Transl. Med. 5 47. 

Ye, R.W. Tao, W Bedzyk, L Young, T Chen, M Li, L. Global gene expression profiles of Bacillus subtilis grown under anaerobic conditions. J. Bacteriol. 2000,182, 4458-4465. 

Liu, H., J. Lin, and K. Roy. 2006a. Effect of 3D scaffold and dynamic culture condition on the global gene expression profile of mouse embryonic stem cells. Biomaterials 27(36) 5978-89. 

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