Fermentation process biotechnology

Abdel-Rahman M.A., Tashiro Y. and Sonomoto K. Recent advances in lactic acid production by microbial fermentation processes. Biotechnology Advances 31 (6) (2013) 877-902. 

Phflippidis, G.P., Smith, T.K., Wyman, C.E., 1993. Study of the enzymatic hydrolysis of cellulose for production of fuel ethanol by the simultaneous saccharification and fermentation process. Biotechnology and Bioengineering 41, 846-853. 

Biotechnological processes may be divided into fermentation processes and biotransformations. In a fermentation process, products are formed from components in the fermentation broth, as primary or secondary metabolites, by microorganisms or higher cells. Product examples are amino acids, vitamins, or antibiotics such as penicillin or cephalosporin. In these cases, co-solvents are sometimes used for in situ product extraction. 

In the interdisciplinary field of biophysics and biotechnology, the bioeffects of electric field have received considerable interest for both fundamental studies on these interaction mechanisms and potential application. However, the effects of pulsed electric field (PEF) on secondary metabolism in plant cell cultures and fermentation processes have been unknown. Therefore, it would be very interesting to find out whether PEF could be used as a new tool for stimulating secondary metabolism in plant cell cultures for potential application to the value-added plant-specific secondary metabolite production. Furthermore, if the PEF permeabilization and elicitation are discovered in a cell culture system, the combination of... 

Recent advances in biotechnology have resulted in improved fermentation processes for the production of useful chemical intermediates. One such process was developed a few years ago during the U.S. DOE sponsored CRADA (Cooperative Research and Development Agreement) with Applied Carbochemicals (ACC). Under this CRADA a consortium of four national labs including Argonne National Laboratory (ANL), Oak Ridge National Laboratory (ORNL), National Renewable Energy Laboratory (NREL), and Pacific... 

Shell" and Biotechnology. Xanthan is manufactured by fermentation, a biotechnological process. How could "Shell", an oil company, be interested in such processes The Royal Dutch/Shell Group is, however, no newcomer to biotechnology. The Milstead Laboratory of Chemical Enzymology was set up in 1962 and was headed by Professor John Cornforth, who went on to win the 1975 Nobel prize for Chemistry shortly after he retired. In 1970 a fermentation laboratory was built on the same site. 

Hosobuchi, M., Kurosawa, K. and Yoshikawa, H. (1993) Application of computer on monitoring and control of fermentation process microbial conversion of ML-236B sodium to pravastatin. Biotechnology and Bioengineering, 42, 815-820. 

J.F. van Impe and G. Bastin. Advanced Instrumentation, Data Interpretation, and Control of Biotechnological Processes, chapter Optimal Adaptive Control of Fed-Batch Fermentation Process, pages 401-435. Kluwer Academic Publishers,... 

It is a method of elemental analysis for various practical reasons and it is essentially suitable for analysis only of metals. A large number of elements can be analyzed for at trace levels. Therefore, its biotechnologic applications mainly involve in measurement of inorganic elements such as alkali, trace, and heavy metals in biological investigations. It is also used in industry to monitor contaminating inorganic elements in bioreactors fermentation process and preparation of culture media. 

S. Elnashaie, G. Ibrahim, Heterogeneous Modeling for the Alcoholic Fermentation Process, Applied Biochemistry and Biotechnology, 19(1), 71-101, 1988... 

Today, many different fermentation processes are applied in industry. They range from large-scale low-tech processes, like wastewater treatment to very sophisticated biotechnology processes to produce... 

Benzylpenicillin (penicillin G, originally just penicillin ) is the first antibiotic to have been manufactured in bulk. It is still universally prescribed and is also used as input material for some semisynthetic antibiotics (Chapter 10). Developments associated with the penicillin fermentation process have been a significant factor in the development of modern biotechnology and therefore it is an appropriate example to illustrate key aspects of manufacture. 

Insulin is an early and classic example of a biotechnology product. It illustrates some of the general problems that are associated with peptide drugs and how modem technology leads to improved therapy. Prior to the production of human insulin by cell-based fermentation processes, treatment was with pancreatic extracts of porcine or bovine origin. Many patients developed insulin resistance, and... 

With most biotechnologically produced flavour extracts the taste quality of natural fermentation processes can be reached and even surpassed. Normally the taste intensity is significantly higher compared to the usual fermentation process in the raw food material. Even completely new taste types may be accessible biotechnologically. The time necessary for the development of the desired taste in most cases may be signifi-... 

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